YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|49258688, gi\|...
Organism:	Clostridium butyricum
Length:	787 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49258688, gi|....

Description	E-value	Query Range	Subject Range
gi\|149905338, gi... - gi\|82744679\|ref\|ZP_00907194.1\| Pyruvate formate-lyase [Clostridium beijerincki NCIMB 8052], gi\|82727...	1016.0	[0..1]	[787..1]
gi\|77918998, gi\|... - gi\|77918998\|ref\|YP_356813.1\| glycerol dehydratase [Pelobacter carbinolicus DSM 2380], gi\|77545081\|gb...	1004.0	[0..8]	[785..15]
gi\|28210647, gi\|... - gi\|28210647\|ref\|NP_781591.1\| formate acetyltransferase 2 [Clostridium tetani E88], gi\|28203085\|gb\|AA...	996.0	[0..2]	[786..4]
gi\|83575153, gi\|... - gi\|83592239\|ref\|YP_425991.1\| pyruvate formate-lyase [Rhodospirillum rubrum ATCC 11170], gi\|83575153\|...	993.0	[0..1]	[787..1]
gi\|115515569, gi... - gi\|117626445\|ref\|YP_859768.1\| putative pyruvate formate-lyase [Escherichia coli APEC O1], gi\|1155155... gi\|226901670, gi... - gi\|237703758\|ref\|ZP_04534239.1\| pyruvate formate-lyase [Escherichia sp. 3_2_53FAA], gi\|226901670\|gb\|... gi\|26250357, gi\|... - gi\|26250357\|ref\|NP_756397.1\| hypothetical protein c4537 [Escherichia coli CFT073], gi\|26110787\|gb\|AA... gi\|218368020, gi... - gi\|218561251\|ref\|YP_002394164.1\| putative Formate C-acetyltransferase [Escherichia coli S88], gi\|218... gi\|218428683, gi... - gi\|218691119\|ref\|YP_002399331.1\| putative Formate C-acetyltransferase [Escherichia coli ED1a], gi\|21... gi\|194437773, gi... - gi\|194437773\|ref\|ZP_03069868.1\| pyruvate formate-lyase [Escherichia coli 101-1], gi\|194423269\|gb\|EDX...	979.0	[0..1]	[787..1]
gi\|90104689, gi\|... - gi\|90422675\|ref\|YP_531045.1\| pyruvate formate-lyase [Rhodopseudomonas palustris BisB18], gi\|90104689...	978.0	[0..1]	[787..1]
gi\|77814517, gi\|... - gi\|77814517\|ref\|ZP_00813776.1\| Pyruvate formate-lyase [Shewanella putrefaciens CN-32], gi\|77810564\|g... gi\|82742221, gi\|... - gi\|82742221\|ref\|ZP_00904921.1\| Pyruvate formate-lyase [Shewanella sp. W3-18-1], gi\|82720429\|gb\|EAP55...	971.0	[0..2]	[785..4]
gi\|77685242, gi\|... - gi\|77685242\|ref\|ZP_00800648.1\| Formate C-acetyltransferase [Alkaliphilus metalliredigenes QYMF], gi\|...	959.0	[0..8]	[784..56]
gi\|225376082, gi... - gi\|225376082\|ref\|ZP_03753303.1\| hypothetical protein ROSEINA2194_01719 [Roseburia inulinivorans DSM ... gi\|83596382 - gi\|83596382\|gb\|ABC25539.1\| glycerol dehydratase [Roseburia inulinivorans]	957.0	[0..10]	[786..12]
gi\|83586691 - gi\|83586691\|ref\|ZP_00925323.1\| COG1882: Pyruvate-formate lyase [Escherichia coli 101-1]	956.0	[0..20]	[787..2]

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Predicted Domain #1

Region A:
Residues: [1-787]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISKGFSTQT ERINILKAQI LNAKPCVESE RAILITESFK QTEGQPAILR RALALKHILE  60
   61 NIPITIRDQE LIVGSLTKEP RSSQVFPEFS NKWLQDELDR LNKRTGDAFQ ISEESKEKLK 120
  121 DVFEYWNGKT TSELATSYMT EETREAVNCD VFTVGNYYYN GVGHVSVDYG KVLRVGFNGI 180
  181 INEAKEQLEK NRSIDPDFIK KEKFLNSVII SCEAAITYVN RYAKKAKEIA DNTSDAKRKA 240
  241 ELNEIAKICS KVSGEGAKSF YEACQLFWFI HAIINIESNG HSISPARFDQ YMYPYYENDK 300
  301 NITDKFAQEL IDCIWIKLND INKVRDEIST KHFGGYPMYQ NLIVGGQNSE GKDATNKVSY 360
  361 MALEAAVHVK LPQPSLSVRI WNKTPDEFLL RAAELTREGL GLPAYYNDEV IIPALVSRGL 420
  421 TLEDARDYGI IGCVEPQKPG KTEGWHDSAF FNLARIVELT INSGFDKNKQ IGPKTQNFEE 480
  481 MKSFDEFMKA YKAQMEYFVK HMCCADNCID IAHAERAPLP FLSSMVDNCI GKGKSLQDGG 540
  541 AEYNFSGPQG VGVANIGDSL VAVKKIVFDE NKITPSELKK TLNNDFKNSE EIQALLKNAP 600
  601 KFGNDIDEVD NLAREGALVY CREVNKYTNP RGGNFQPGLY PSSINVYFGS LTGATPDGRK 660
  661 SGQPLADGVS PSRGCDVSGP TAACNSVSKL DHFIASNGTL FNQKFHPSAL KGDNGLMNLS 720
  721 SLIRSYFDQK GFHVQFNVID KKILLAAQKN PEKYQDLIVR VAGYSAQFIS LDKSIQNDII 780
  781 ARTEHVM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1r8wA
Description:	Native structure of the B12-independent glycerol dehydratase from clostridium butyricum
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.95058695475279	bayes_pls_golite062009
oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	1.72563679072631	bayes_pls_golite062009
formate C-acetyltransferase activity	1.48261557970472	bayes_pls_golite062009
oxidoreductase activity, acting on CH or CH2 groups	1.43559439297918	bayes_pls_golite062009
oxidoreductase activity	1.42705638794743	bayes_pls_golite062009
ribonucleoside-diphosphate reductase activity	1.37298861502572	bayes_pls_golite062009
C-acyltransferase activity	0.0923196663496405	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: