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View Structure Prediction Details

Protein: IF4G1_ARATH
Organism: Arabidopsis thaliana
Length: 780 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IF4G1_ARATH.

Description E-value Query
Range
Subject
Range
gi|23306434, gi|... - gi|28059736|gb|AAO30087.1| eukaryotic initiation factor 4, eIF4-like protein [Arabidopsis thaliana],...
635.0 [0..1] [780..1]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQGDQTVLS LRPGGGRGNR LFGSSSSSSS LSFGSLSSSD LPLLRPHGGA PASSFPFKGG  60
   61 DSRFDGRERV KYTREQLLEL KETTQLSDEI LRVQRETAAE LFGEEGTWAR GESVVSNLVP 120
  121 VQSASRFSEP DSRDWRSRST QP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.69897
Match: 1rf8B
Description: Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [143-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPSGEERSWD NLREAKDSRY VEASQYNRQD QPNSQFSRAN ISSNQGGGPA PVLVKAEVPW  60
   61 SARRGNLSEN DRVLK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [218-484]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVKGILNKLT PEKYDLLKGQ LIESGITSAD ILKGVITLIF DKAVLEPTFC PMYAKLCSDI  60
   61 NDQLPTFPPA EPGDKEITFK RVLLNICQEA FEGASQLREE LRQMSAPDQE AERNDKEKLL 120
  121 KLKTLGNIRL IGELLKQKMV PEKIVHHIVQ ELLGADEKVC PAEENVEAIC HFFKTIGKQL 180
  181 DGNVKSKRIN DVYFKRLQAL SKNPQLELRL RFMVQNIIDM RSNGWVPRRE EMKARTITEI 240
  241 HTEAEKNLGL RPGATANMRR GMVSSGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.30103
Match: 1hu3A
Description: Eukaryotic initiation factor eIF4G
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.373576425899935 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [485-557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVSPGPVYPG GRPGAGGLMP GMPGTRRMPG MPGVDNDNWE VPRTRSMSRR DGPGPLHSPA  60
   61 VSKSASMNTR LLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [558-780]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGSSGIMSGK TSALLQGSGS VSRPVTVSAE RPAQSVAPLT VPVPVEKPQP SGPKLSEEVL  60
   61 QRKTKSLLEE YFNVRLLGEA LQCVEELGLP SYHPEFVKEA ISLSLEKSPP VVEPIATLLE 120
  121 YLLSKKVVAP KDLETGFLLY GAMLDDIGID LPKAPNNFGE IVGKLILAGG VDFKLVREII 180
  181 GKMEDDRFQK MVVDAAVRIV ESSEQGKSLL ASQAADIEAC RNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.39794
Match: 1ug3A
Description: C-terminal portion of human eIF4GI
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle