YRC Public Data Repository - Protein Structure Prediction

Protein:	DCP2_ARATH
Organism:	Arabidopsis thaliana
Length:	373 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DCP2_ARATH.

Description	E-value	Query Range	Subject Range
gi\|9758022 - gi\|9758022\|dbj\|BAB08683.1\| unnamed protein product [Arabidopsis thaliana]	326.0	[0..1]	[373..1]
gi\|114672436 - gi\|114672436\|ref\|XP_001147066.1\| PREDICTED: similar to DCP2 protein isoform 1 [Pan troglodytes]	296.0	[0..23]	[368..12]
DCP2_PONPY - mRNA-decapping enzyme 2 - Pongo pygmaeus (Orangutan) DCP2_PONAB - m7GpppN-mRNA hydrolase OS=Pongo abelii GN=DCP2 PE=2 SV=1	295.0	[0..23]	[368..12]
gi\|109078232 - gi\|109078232\|ref\|XP_001082402.1\| PREDICTED: similar to DCP2 decapping enzyme isoform 1 [Macaca mulat...	295.0	[0..23]	[368..12]
gi\|40352976, gi\|... - gi\|40352976\|gb\|AAH64593.1\| DCP2 protein [Homo sapiens], gi\|119569375\|gb\|EAW48990.1\| DCP2 decapping e...	294.0	[0..23]	[368..12]
gi\|109506558, gi... - gi\|109514053\|ref\|XP_001055777.1\| PREDICTED: similar to mRNA decapping enzyme 2 [Rattus norvegicus], ...	278.0	[0..23]	[368..85]

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Predicted Domain #1

Region A:
Residues: [1-247]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGLHRSSSS SKNIGNCLPS KELLDDLCSR FVLNVPEEDQ QSFERILFLV EYAYWYYEDN  60
   61 AVENDPKLKS LSLKEFTSLL FNSCDVLRPY VTHIDDIFKD FTSYKCRVPV TGAIILDETY 120
  121 ERCLLVKGWK GSSWSFPRGK KSKDEEDHAC AIREVLEETG FDVSKLLKRE EYIEFVFRQQ 180
  181 RVRLYIVAGV TEDTVFAPLT KKEISEITWH RLDHLQPASN EVITHGVSGL KLYMVAPFLS 240
  241 SLKSWIL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.69897
Match:	2a6tA
Description:	Crystal structure of S.pombe mRNA decapping enzyme Dcp2p
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [248-373]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KHPSPVARRP NKPLKALCVW NARTSVGGNG TATVESQNRK SELRTTTMES NSRKPELKRT  60
   61 TMESHSTKPE LRKGTMESHN TTATVESHNT KPVVDHSQDI KPGGSFINFK FNQSVILQAL 120
  121 ESGNSA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.445	a.85.1	Hemocyanin, N-terminal domain
View	Download	0.408	a.279.1	Description not found.
View	Download	0.376	b.42.2	Ricin B-like lectins
View	Download	0.343	a.45.1	Glutathione S-transferase (GST), C-terminal domain
View	Download	0.311	a.60.8	HRDC-like
View	Download	0.232	d.38.1	Thioesterase/thiol ester dehydrase-isomerase
View	Download	0.201	d.26.1	FKBP-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits