YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|254742799
Organism:	Bacillus anthracis str. Kruger B
Length:	485 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|254742799.

Description	E-value	Query Range	Subject Range
gi\|47568603, gi\|... - gi\|47568603\|ref\|ZP_00239301.1\| proline/betaine transporter [Bacillus cereus G9241], gi\|47554699\|gb\|E...	5.0E-60	[1..485]	[1..485]
gi\|42782112, gi\|... - gi\|42782112\|ref\|NP_979359.1\| major facilitator superfamily protein superfamily [Bacillus cereus ATCC...	7.0E-60	[1..485]	[1..485]
gi\|29896668, gi\|... - gi\|30021115\|ref\|NP_832746.1\| proline/betaine transporter [Bacillus cereus ATCC 14579], gi\|29896668\|g...	9.0E-60	[1..485]	[1..485]
gi\|52142504, gi\|... - gi\|52142504\|ref\|YP_084325.1\| glycine betaine/L-proline ABC transporter, permease [Bacillus cereus E3...	1.0E-59	[1..485]	[1..485]
gi\|163862954, gi... - gi\|89207137\|ref\|ZP_01185684.1\| General substrate transporter:Major facilitator superfamily MFS_1 [Ba...	2.0E-59	[1..483]	[1..483]
gi\|67668083, gi\|... - gi\|67668083\|ref\|ZP_00465278.1\| General substrate transporter:Major facilitator superfamily [Burkhold...	2.0E-55	[8..448]	[1028..1479]
gi\|67536615, gi\|... - gi\|67542336\|ref\|ZP_00420273.1\| General substrate transporter:Major facilitator superfamily [Burkhold...	4.0E-53	[3..471]	[257..724]
gi\|89150839, gi\|... - gi\|89201070\|ref\|ZP_01179817.1\| General substrate transporter:Major facilitator superfamily MFS_1 [Ba...	4.0E-52	[1..480]	[1..482]
gi\|169764102 - gi\|169764102\|ref\|XP_001727951.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83770979 - gi\|83770979\|dbj\|BAE61112.1\| unnamed protein product [Aspergillus oryzae]	2.0E-49	[1..452]	[192..657]
gi\|50085380, gi\|... - gi\|50085380\|ref\|YP_046890.1\| proline/glycine betaine transporter [Acinetobacter sp. ADP1], gi\|495313...	5.0E-49	[31..481]	[42..492]

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Predicted Domain #1

Region A:
Residues: [1-485]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQNNDLNFE PQDVNIVNPK QARKAVVATG IGNAMEWFDF GLYAYLAVIL SQLFFSGVDN  60
   61 SGLQLVLTFG TFAAAFLVRP IGGVFFGRIG DKYGRKIVLS TTIILMALST LFIALLPTYE 120
  121 QIGVWAPILL LVARMIQGFS TGGEYSGAMV YIAESSPDKK RGILGSGLEI GTLSGYIAAS 180
  181 VIVTILTLLL TDEQMLSWGW RIPFLIAAPI GLVGLYLRRH LDESPIFEEM EKAQEESEDN 240
  241 EQFSFMDIIK YHKKDFLLST VIVAFFNITN YMILSYIPSY LTQVLKVKET TGLLIISITM 300
  301 ALMIPLALYF GKLSDKIGNK RVVQIGLLGL TVFAIPAFLL IGNGHIAAIF AGIFVLGFFL 360
  361 SVYEGTLPSL LPSLFFTDVR YRALSISFNI SVSIFGGTTP LVCSYLVHAT GNPLAPAFYL 420
  421 TGVSIIGLVV FSVLFVTTSG RALKGSYPTV ETKKEAHQIA KEDPEETLWW HEESLEIEAG 480
  481 KNASI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.39794
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.54194478414824	bayes_pls_golite062009
ion transmembrane transporter activity	2.21266150105753	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.15783210522667	bayes_pls_golite062009
cation transmembrane transporter activity	1.79369588808394	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
binding	0.805286077372817	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: