YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|254721328
Organism:	Bacillus anthracis str. A1055
Length:	453 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|254721328.

Description	E-value	Query Range	Subject Range
gi\|51976913, gi\|... - gi\|52143444\|ref\|YP_083385.1\| sensor histidine kinase [Bacillus cereus E33L], gi\|51976913\|gb\|AAU18463...	1.0E-87	[1..453]	[1..453]
gi\|47553480, gi\|... - gi\|47569834\|ref\|ZP_00240503.1\| sensor histidine kinase, putative [Bacillus cereus G9241], gi\|4755348...	1.0E-86	[1..453]	[1..453]
gi\|42737049, gi\|... - gi\|42781128\|ref\|NP_978375.1\| sensor histidine kinase [Bacillus cereus ATCC 10987], gi\|42737049\|gb\|AA...	2.0E-86	[1..453]	[1..453]
gi\|20808918 - gi\|20808918\|ref\|NP_624089.1\| Sensory transduction histidine kinase [Thermoanaerobacter tengcongensis... gi\|20808918, gi\|... - gi\|20808918\|ref\|NP_624089.1\| sensory transduction histidine kinase [Thermoanaerobacter tengcongensis...	1.0E-79	[3..453]	[8..466]
gi\|30020112, gi\|... - gi\|30020112\|ref\|NP_831743.1\| two component system histidine kinase [Bacillus cereus ATCC 14579], gi\|... gi\|228656027, gi... - gi\|229127408\|ref\|ZP_04256402.1\| hypothetical protein bcere0015_18590 [Bacillus cereus BDRD-Cer4], gi...	1.0E-78	[10..453]	[1..443]
gi\|166853488, gi... - gi\|167039248\|ref\|YP_001662233.1\| integral membrane sensor signal transduction histidine kinase [Ther... gi\|241904558, gi... - gi\|241904558\|ref\|ZP_04789245.1\| histidine kinase [Thermoanaerobacter brockii subsp. finnii Ako-1], g... gi\|76588655, gi\|... - gi\|76795887\|ref\|ZP_00778257.1\| ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidi...	1.0E-76	[22..451]	[27..465]
gi\|45358866, gi\|... - gi\|45358866\|ref\|NP_988423.1\| sensory transduction histidine kinase [Methanococcus maripaludis S2], g...	1.0E-74	[123..453]	[277..634]
gi\|222053516, gi... - gi\|222053516\|ref\|YP_002535878.1\| histidine kinase [Geobacter sp. FRC-32], gi\|221562805\|gb\|ACM18777.1...	2.0E-74	[1..453]	[7..467]

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Predicted Domain #1

Region A:
Residues: [1-84]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRKVTLYFM TVIILMLVLF EVVFSVSVYR YYYNGIVQYV ESHAKTSTRF FSEYNSLYFI  60
   61 RLQEYSGDII ESFQLEGTEL QLID

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [85-211]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RHGTIIQSSS GEKTEGKVVI PYSLLEGEMY HQVTTTKDKV KQLEVISPLI HQGQTIGVLK  60
   61 YTTVLTHVNA KIIEIIMFTI CVGIVISGIV FLISRRLANS FVKPIESIIH ASSQIAEGTL 120
  121 KKKIKED

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.62
Match:	2f95B
Description:	M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [212-453]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YPGELGELAH SLNHMSDKIE KAEQMKNEFI ASISHEIRTP LTGIKGWSET LKTVDHLTEE  60
   61 EIKQGMGIIS GETDRLIHLV EELLDFSRLQ SNHFNLYKQK VQLYDILEET IWQLTPNAEE 120
  121 KKMQFIKTIE RIELIGDRNR LKQIFLNIVQ NAIKYSHENG KVYIEATKNE GQAVIKVKDD 180
  181 GIGIAKEHLP YIEQSFYQIN NHATGAGLGL AIVKKMVELH GGTINIISKE GIGTTILIKL 240
  241 PL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.522879
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits