YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|254682540
Organism:	Bacillus anthracis str. CNEVA-9066
Length:	466 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|254682540.

Description	E-value	Query Range	Subject Range
gi\|52144035, gi\|... - gi\|52144035\|ref\|YP_082793.1\| sensor histidine kinase [Bacillus cereus E33L], gi\|51977504\|gb\|AAU19054...	4.0E-85	[1..466]	[1..466]
gi\|47556739, gi\|... - gi\|47566186\|ref\|ZP_00237214.1\| histidin [Bacillus cereus G9241], gi\|47556739\|gb\|EAL15070.1\| histidin...	1.0E-84	[1..466]	[1..466]
gi\|42780488, gi\|... - gi\|42780488\|ref\|NP_977735.1\| sensor histidine kinase [Bacillus cereus ATCC 10987], gi\|42736407\|gb\|AA...	4.0E-84	[1..466]	[1..466]
gi\|65318667 - gi\|65318667\|ref\|ZP_00391626.1\| COG0642: Signal transduction histidine kinase [Bacillus anthracis str...	5.0E-83	[7..466]	[4..463]
gi\|228957670, gi... - gi\|228957670\|ref\|ZP_04119417.1\| hypothetical protein bthur0005_11870 [Bacillus thuringiensis serovar... gi\|229144004, gi... - gi\|229144004\|ref\|ZP_04272420.1\| hypothetical protein bcere0012_11670 [Bacillus cereus BDRD-ST24], gi... gi\|228656655, gi... - gi\|229126715\|ref\|ZP_04255727.1\| hypothetical protein bcere0015_11720 [Bacillus cereus BDRD-Cer4], gi... gi\|228674624, gi... - gi\|229108855\|ref\|ZP_04238460.1\| hypothetical protein bcere0018_11320 [Bacillus cereus Rock1-15], gi\|... gi\|228726198, gi... - gi\|229043139\|ref\|ZP_04190864.1\| hypothetical protein bcere0027_11940 [Bacillus cereus AH676], gi\|228... gi\|218162932, gi... - gi\|218234975\|ref\|YP_002366083.1\| sensor histidine kinase [Bacillus cereus B4264], gi\|218162932\|gb\|AC... gi\|229149600, gi... - gi\|229149600\|ref\|ZP_04277832.1\| hypothetical protein bcere0011_11600 [Bacillus cereus m1550], gi\|228... gi\|30019452, gi\|... - gi\|30019452\|ref\|NP_831083.1\| two component system histidine kinase [Bacillus cereus ATCC 14579], gi\|...	1.0E-81	[1..466]	[1..466]
gi\|163939207, gi... - gi\|89204473\|ref\|ZP_01183050.1\| ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidi...	4.0E-81	[1..466]	[1..466]
gi\|228859665, gi... - gi\|228899979\|ref\|ZP_04064217.1\| hypothetical protein bthur0014_11890 [Bacillus thuringiensis IBL 422... gi\|75759998, gi\|... - gi\|75759998\|ref\|ZP_00740065.1\| Two component system histidine kinase [Bacillus thuringiensis serovar...	2.0E-79	[1..466]	[1..466]
gi\|152023578, gi... - gi\|89200930\|ref\|ZP_01179679.1\| ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidi...	2.0E-78	[1..457]	[1..456]
gi\|222053516, gi... - gi\|222053516\|ref\|YP_002535878.1\| histidine kinase [Geobacter sp. FRC-32], gi\|221562805\|gb\|ACM18777.1...	2.0E-75	[2..461]	[5..469]

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Predicted Domain #1

Region A:
Residues: [1-75]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTMVQKLWL TVVCAVFVTV SFLYFVSLYS YEKLYVDNLK DSLVMEGKRL AAQYDKSEGI  60
   61 STFEEKVRAF DQISS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [76-213]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDVLFVSNPR DLSACLPFDV HHHSLISEGD RQALLDGKTV TKIGYEEHFE RNIMGVVIPV  60
   61 LENKKLVGIV YSYIPLKSIK DLIYDMGLIL APLALAITLL TIWIGRKIII AITRPLSQME 120
  121 RVANHLATGD FSERITIS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.63
Match:	2f95B
Description:	M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [214-466]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEDEIGRLGK AFNKMANSLE TEDVKRKEFL ANVSHELRTP LSYIKGYSEA ILDGVAKGPQ  60
   61 QEKVTQLIHK EADRMQRLVH DLLDLAQLEG EHFPLQKQPI VFSQLIEDVL DTYEIKFIEK 120
  121 KIRISTNLNP EIIVMIDEDR MQQVLHNVLD NAIRYTNQNG DIMITLRQID DYCELSIKDT 180
  181 GIGIDTEHLE NLGERFYRVD KARSRQHGGT GLGLAIVRQI VHIHDGQWQI ESEKGNGTTV 240
  241 SIKLKVQNEE SMF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.69897
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits