YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|254672243
Organism:	Neisseria meningitidis alpha275
Length:	148 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|254672243.

Description	E-value	Query Range	Subject Range
gi\|240117666 - gi\|240117666\|ref\|ZP_04731728.1\| putative acyl-CoA hydrolase [Neisseria gonorrhoeae PID1] gi\|240115362 - gi\|240115362\|ref\|ZP_04729424.1\| putative acyl-CoA hydrolase [Neisseria gonorrhoeae PID18] gi\|240112616 - gi\|240112616\|ref\|ZP_04727106.1\| putative acyl-CoA hydrolase [Neisseria gonorrhoeae MS11] gi\|240081017 - gi\|240081017\|ref\|ZP_04725560.1\| putative acyl-CoA hydrolase [Neisseria gonorrhoeae FA19] gi\|226512458, gi... - gi\|254493418\|ref\|ZP_05106589.1\| acyl-CoA hydrolase [Neisseria gonorrhoeae 1291], gi\|226512458\|gb\|EEH... gi\|240127901 - gi\|240127901\|ref\|ZP_04740562.1\| putative acyl-CoA hydrolase [Neisseria gonorrhoeae SK-93-1035] gi\|240123221 - gi\|240123221\|ref\|ZP_04736177.1\| putative acyl-CoA hydrolase [Neisseria gonorrhoeae PID332] gi\|59718340, gi\|... - gi\|59801445\|ref\|YP_208157.1\| putative acyl-CoA hydrolase [Neisseria gonorrhoeae FA 1090], gi\|5971834... gi\|239998695 - gi\|239998695\|ref\|ZP_04718619.1\| putative acyl-CoA hydrolase [Neisseria gonorrhoeae 35/02]	159.0	[0..1]	[148..1]
gi\|75437779, gi\|... - gi\|75437779\|ref\|ZP_00733503.1\| acyl-CoA hydrolase [Actinobacillus succinogenes 130Z], gi\|74275749\|gb...	158.0	[0..1]	[146..1]
gi\|11281876 - pir\|\|E81878 probable acyl-CoA hydrolase NMA1121 [imported] - Neisseria meningitidis (strain Z2491 se... gi\|7379815, gi\|2... - gi\|7379815\|emb\|CAB84383.1\| putative acyl-CoA hydrolase [Neisseria meningitidis Z2491], gi\|218768012\|...	158.0	[0..1]	[148..1]
gi\|52424791, gi\|... - gi\|52424791\|ref\|YP_087928.1\| hypothetical protein MS0736 [Mannheimia succiniciproducens MBEL55E], gi...	156.0	[0..1]	[146..1]
gi\|47168418, gi\|... - gi\|60594418\|pdb\|1YLI\|B Chain B, Crystal Structure Of Hi0827, A Hexameric Broad Specificity Acyl-Coen...	153.0	[0..11]	[146..12]
gi\|145632186, gi... - gi\|145632186\|ref\|ZP_01787921.1\| hypothetical protein CGSHi3655_07024 [Haemophilus influenzae 3655], ... Y827_HAEIN - Uncharacterized acyl-CoA thioester hydrolase HI_0827 OS=Haemophilus influenzae (strain ATCC 51907 / ... Y827_HAEIN, YCIA... - (P44886) Putative acyl-CoA thioester hydrolase HI0827 (EC 3.1.2.-), Uncharacterized acyl-CoA thioest... gi\|229844695, gi... - gi\|229844695\|ref\|ZP_04464834.1\| hypothetical protein CGSHi6P18H1_03774 [Haemophilus influenzae 6P18H... gi\|145274446, gi... - gi\|145640932\|ref\|ZP_01796514.1\| hypothetical protein CGSHiR3021_07682 [Haemophilus influenzae R3021]... gi\|145640932 - gi\|145640932\|ref\|ZP_01796514.1\| hypothetical protein CGSHiR3021_07682 [Haemophilus influenzae R3021] gi\|145634761, gi... - gi\|145634761\|ref\|ZP_01790469.1\| Trp operon repressor [Haemophilus influenzae PittAA], gi\|145267927\|g...	153.0	[0..11]	[146..13]
gi\|144983966 - gi\|144983966\|gb\|EDJ91408.1\| putative acyl-CoA thioester hydrolase [Haemophilus influenzae R3021] gi\|48867705, gi\|... - gi\|68249422\|ref\|YP_248534.1\| putative acyl-CoA thioester hydrolase [Haemophilus influenzae 86-028NP]... gi\|145638371, gi... - gi\|145638371\|ref\|ZP_01793981.1\| Trp operon repressor [Haemophilus influenzae PittII], gi\|145272700\|g... gi\|46133151 - gi\|46133151\|ref\|ZP_00203092.1\| COG1607: Acyl-CoA hydrolase [Haemophilus influenzae R2866] gi\|145270139, gi... - gi\|145636613\|ref\|ZP_01792280.1\| Trp operon repressor [Haemophilus influenzae PittHH], gi\|145270139\|g... gi\|145630576 - gi\|145630576\|ref\|ZP_01786356.1\| putative acyl-CoA thioester hydrolase [Haemophilus influenzae 22.4-2...	152.0	[0..11]	[146..13]
gi\|148716688, gi... - gi\|148826528\|ref\|YP_001291281.1\| Trp operon repressor [Haemophilus influenzae PittEE], gi\|148716688\|... gi\|46129192 - gi\|46129192\|ref\|ZP_00202029.1\| COG1607: Acyl-CoA hydrolase [Haemophilus influenzae R2846] gi\|229845878, gi... - gi\|229845878\|ref\|ZP_04465990.1\| Trp operon repressor [Haemophilus influenzae 7P49H1], gi\|229810882\|g...	152.0	[0..11]	[145..13]
gi\|32030358, gi\|... - gi\|32030358\|ref\|ZP_00133225.1\| COG1607: Acyl-CoA hydrolase [Haemophilus somnus 2336], gi\|170718964\|r... gi\|23467209, gi\|... - gi\|23467209\|ref\|ZP_00122793.1\| COG1607: Acyl-CoA hydrolase [Haemophilus somnus 129PT], gi\|113461411\|...	152.0	[0..4]	[146..6]
gi\|33152729, gi\|... - gi\|33152729\|ref\|NP_874082.1\| putative acyl CoA thioester hydrolase [Haemophilus ducreyi 35000HP], gi...	150.0	[0..5]	[145..4]

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Predicted Domain #1

Region A:
Residues: [1-148]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQHEEGNRQR PQGELLLRTV AMPRDTNPNQ DIFGGWIMSQ MDLGGGILAA EIARGRIVTV  60
   61 AVQEMNFIRP VKVGNVVCCY GHCVRVGNTS LQLKVDVWVK TLMNDCVTED RYLVTEAVFT 120
  121 YVAIDAEGNP RPIPKEGNPK LAGLLPTP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.0
Match:	1yliA
Description:	Structure of HI0827, a thioesterase acting on short-chain acyl-CoA compounds
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.11649534052993	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: