YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|227553950, gi...
Organism:	Enterococcus faecalis HH22
Length:	287 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|227553950, gi....

Description	E-value	Query Range	Subject Range
KHSE_LISIN - Homoserine kinase OS=Listeria innocua GN=thrB PE=3 SV=1 KHSE_LISIN - Homoserine kinase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=thrB PE=3 SV=1	229.0	[0..1]	[287..1]
KHSE_BACWK - Homoserine kinase OS=Bacillus weihenstephanensis (strain KBAB4) GN=thrB PE=3 SV=1	226.0	[0..1]	[286..4]
KHSE_BACCZ - Homoserine kinase OS=Bacillus cereus (strain ZK / E33L) GN=thrB PE=3 SV=1	226.0	[0..3]	[286..6]
KHSE_BACHK - Homoserine kinase OS=Bacillus thuringiensis subsp. konkukian GN=thrB PE=3 SV=1 gi\|254721322 - gi\|254721322\|ref\|ZP_05183112.1\| homoserine kinase [Bacillus anthracis str. A1055] KHSE_BACC0 - Homoserine kinase OS=Bacillus cereus (strain AH820) GN=thrB PE=3 SV=1 KHSE_BACHK - Homoserine kinase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=thrB PE=3 SV=1 gi\|195990432, gi... - gi\|196036959\|ref\|ZP_03104336.1\| homoserine kinase [Bacillus cereus W], gi\|195990432\|gb\|EDX54423.1\| h...	226.0	[0..3]	[286..6]
KHSE_BACAC - Homoserine kinase OS=Bacillus anthracis (strain CDC 684 / NRRL 3495) GN=thrB PE=3 SV=1 KHSE_BACAA - Homoserine kinase OS=Bacillus anthracis (strain A0248) GN=thrB PE=3 SV=1 gi\|21399845, gi\|... - gi\|65319282\|ref\|ZP_00392241.1\| COG0083: Homoserine kinase [Bacillus anthracis str. A2012], ref\|NP_65... gi\|254684564 - gi\|254684564\|ref\|ZP_05148424.1\| homoserine kinase [Bacillus anthracis str. CNEVA-9066] gi\|254734868 - gi\|254734868\|ref\|ZP_05192580.1\| homoserine kinase [Bacillus anthracis str. Western North America USA... gi\|254741268 - gi\|254741268\|ref\|ZP_05198956.1\| homoserine kinase [Bacillus anthracis str. Kruger B] gi\|254750819 - gi\|254750819\|ref\|ZP_05202858.1\| homoserine kinase [Bacillus anthracis str. Vollum] gi\|254760059 - gi\|254760059\|ref\|ZP_05212083.1\| homoserine kinase [Bacillus anthracis str. Australia 94] gi\|170686545, gi... - gi\|170686545\|ref\|ZP_02877766.1\| homoserine kinase [Bacillus anthracis str. A0465], gi\|170669621\|gb\|E... gi\|170129063, gi... - gi\|170706061\|ref\|ZP_02896523.1\| homoserine kinase [Bacillus anthracis str. A0389], gi\|170129063\|gb\|E... gi\|177650884, gi... - gi\|177650884\|ref\|ZP_02933781.1\| homoserine kinase [Bacillus anthracis str. A0174], gi\|172083345\|gb\|E... gi\|190566239, gi... - gi\|190566239\|ref\|ZP_03019157.1\| homoserine kinase [Bacillus anthracis Tsiankovskii-I], gi\|190562374\|... KHSE_BACAN - Homoserine kinase OS=Bacillus anthracis GN=thrB PE=3 SV=1 gi\|49184839, gi\|... - gi\|49184839\|ref\|YP_028091.1\| homoserine kinase [Bacillus anthracis str. Sterne], gi\|49178766\|gb\|AAT5... gi\|47502413, gi\|... - gi\|47527265\|ref\|YP_018614.1\| homoserine kinase [Bacillus anthracis str. 'Ames Ancestor'], gi\|4750241... gi\|30261999, gi\|... - gi\|30261999\|ref\|NP_844376.1\| homoserine kinase [Bacillus anthracis str. Ames], gi\|30256625\|gb\|AAP258... gi\|164714021, gi... - gi\|165870133\|ref\|ZP_02214789.1\| homoserine kinase [Bacillus anthracis str. A0488], gi\|164714021\|gb\|E... gi\|167632838, gi... - gi\|167632838\|ref\|ZP_02391164.1\| homoserine kinase [Bacillus anthracis str. A0442], gi\|167531650\|gb\|E... gi\|167513643, gi... - gi\|167638342\|ref\|ZP_02396619.1\| homoserine kinase [Bacillus anthracis str. A0193], gi\|167513643\|gb\|E...	226.0	[0..3]	[286..6]
KHSE_BACC1 - Homoserine kinase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=thrB PE=3 SV=1	226.0	[0..3]	[286..6]
KHSE_STRR6 - Homoserine kinase OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) GN=thrB PE=3 SV=1 KHSE_STRPN - Homoserine kinase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) GN=thrB PE=3 ... gi\|237821234 - gi\|237821234\|ref\|ZP_04597079.1\| homoserine kinase [Streptococcus pneumoniae CCRI 1974M2] gi\|237651149 - gi\|237651149\|ref\|ZP_04525401.1\| homoserine kinase [Streptococcus pneumoniae CCRI 1974] KHSE_STRP7 - Homoserine kinase OS=Streptococcus pneumoniae (strain 70585) GN=thrB PE=3 SV=1 KHSE_STRZP - Homoserine kinase OS=Streptococcus pneumoniae (strain P1031) GN=thrB PE=3 SV=1 KHSE_STRZJ - Homoserine kinase OS=Streptococcus pneumoniae (strain JJA) GN=thrB PE=3 SV=1 KHSE_STRPN - Homoserine kinase OS=Streptococcus pneumoniae GN=thrB PE=3 SV=1 gi\|149002736, gi... - gi\|149002736\|ref\|ZP_01827662.1\| homoserine kinase [Streptococcus pneumoniae SP14-BS69], gi\|147759030... gi\|183574347, gi... - gi\|183574347\|gb\|EDT94875.1\| homoserine kinase [Streptococcus pneumoniae CDC0288-04], gi\|168491262\|re... gi\|147756642, gi... - gi\|148997587\|ref\|ZP_01825192.1\| homoserine kinase [Streptococcus pneumoniae SP11-BS70], gi\|147756642... gi\|183576499, gi... - gi\|183576499\|gb\|EDT97027.1\| homoserine kinase [Streptococcus pneumoniae CDC3059-06], gi\|168493262\|re... gi\|147928283, gi... - gi\|148993082\|ref\|ZP_01822676.1\| homoserine kinase [Streptococcus pneumoniae SP9-BS68], gi\|147928283\|... gi\|168575820, gi... - gi\|183578250\|gb\|EDT98778.1\| homoserine kinase [Streptococcus pneumoniae MLV-016], gi\|168575820\|ref\|Z... gi\|148989479, gi... - gi\|148989479\|ref\|ZP_01820838.1\| homoserine kinase [Streptococcus pneumoniae SP6-BS73], gi\|147925022\|... KHSE_STRPI - Homoserine kinase OS=Streptococcus pneumoniae (strain Hungary19A-6) GN=thrB PE=3 SV=1 gi\|148985690, gi... - gi\|148985690\|ref\|ZP_01818844.1\| homoserine kinase [Streptococcus pneumoniae SP3-BS71], gi\|147922171\|... KHSE_STRPS - Homoserine kinase OS=Streptococcus pneumoniae (strain CGSP14) GN=thrB PE=3 SV=1 KHSE_STRP4 - Homoserine kinase OS=Streptococcus pneumoniae serotype 19F (strain G54) GN=thrB PE=3 SV=1 KHSE_STRPJ - Homoserine kinase OS=Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1) GN=thrB PE=3 SV=1 gi\|172042240, gi... - gi\|172042240\|gb\|EDT50286.1\| homoserine kinase [Streptococcus pneumoniae CDC1873-00], gi\|168484538\|re... gi\|149011594, gi... - gi\|149013231\|ref\|ZP_01834017.1\| homoserine kinase [Streptococcus pneumoniae SP19-BS75], gi\|149011594... gi\|168487358, gi... - gi\|183569771\|gb\|EDT90299.1\| homoserine kinase [Streptococcus pneumoniae CDC1087-00], gi\|168487358\|re... KHSE_STRP2 - Homoserine kinase OS=Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) GN=thrB PE=3 SV=1 gi\|147761294, gi... - gi\|149006990\|ref\|ZP_01830659.1\| homoserine kinase [Streptococcus pneumoniae SP18-BS74], gi\|147761294... gi\|168489522, gi... - gi\|183571970\|gb\|EDT92498.1\| homoserine kinase [Streptococcus pneumoniae SP195], gi\|168489522\|ref\|ZP_...	226.0	[0..1]	[286..1]
gi\|47014677, gi\|... - gi\|47096967\|ref\|ZP_00234543.1\| homoserine kinase [Listeria monocytogenes str. 1/2a F6854], gi\|470146... gi\|127764529, gi... - gi\|254913445\|ref\|ZP_05263457.1\| homoserine kinase [Listeria monocytogenes J2818], gi\|153192201\|ref\|Z... gi\|126942390, gi... - gi\|254900316\|ref\|ZP_05260240.1\| homoserine kinase [Listeria monocytogenes J0161], gi\|153184878\|ref\|Z... gi\|254937826, gi... - gi\|254937826\|ref\|ZP_05269523.1\| homoserine kinase [Listeria monocytogenes F6900], gi\|153180633\|ref\|Z...	225.0	[0..1]	[287..1]
gi\|224503215 - gi\|224503215\|ref\|ZP_03671522.1\| homoserine kinase [Listeria monocytogenes FSL R2-561] KHSE_LISMO - Homoserine kinase OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=thrB PE=1 ... gi\|224500711 - gi\|224500711\|ref\|ZP_03669060.1\| homoserine kinase [Listeria monocytogenes Finland 1988] KHSE_LISMO - Homoserine kinase OS=Listeria monocytogenes GN=thrB PE=1 SV=1	225.0	[0..1]	[287..1]
KHSE_BACCR - Homoserine kinase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 937...	225.0	[0..3]	[286..6]

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Predicted Domain #1

Region A:
Residues: [1-287]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIRVPATSA NLGPGFDSCG IALSAYLTIN VLGESEFWEI QHTLGEEIST NEENLLIQTA  60
   61 LKIAPELTPK VIRMVSDIPL ARGLGSSSSV IVAGIELANR LAHLNLSPKE KVRLATEMEG 120
  121 HPDNVAPAIL GDFVVASHVE NQVYHVKHHF PMCDVIAFIP EEPLFTEKSR AVLPEKLAYK 180
  181 EAVAASSIAN VMIAAILNGD LPLAGKMMEQ DKWHETYRRS LVPHLKEIRR LTQQKGAYGS 240
  241 FLSGAGPTVL ILSPEERTNE IVQSLEKLST KASIQIFNID QEGVQVF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.69897
Match:	1fwkA
Description:	Homoserine kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.836142537655721	bayes_pls_golite062009
structural constituent of ribosome	0.0246382239358082	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: