YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|254814341
Organism:	Mycobacterium tuberculosis KZN 4207
Length:	391 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|254814341.

Description	E-value	Query Range	Subject Range
gi\|71000709, gi\|... - gi\|71000709\|ref\|XP_755036.1\| alpha,alpha-trehalose-phosphate synthase subunit Tps2 [Aspergillus fumi... gi\|159128050 - gi\|159128050\|gb\|EDP53165.1\| alpha,alpha-trehalose-phosphate synthase subunit TPS2, putative [Aspergi...	281.0	[0..3]	[379..545]
gi\|114189402, gi... - gi\|115402959\|ref\|XP_001217556.1\| hypothetical protein ATEG_08970 [Aspergillus terreus NIH2624], gi\|1...	280.0	[0..3]	[379..534]
gi\|60265773, gi\|... - gi\|60265773\|gb\|AAX16015.1\| trehalose-6-phosphate synthase [Ginkgo biloba], gi\|60265771\|gb\|AAX16014.1...	273.0	[0..26]	[386..436]
TPS9_ARATH - Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 9 OS=Arabidopsis thaliana GN=TPS9 PE...	272.0	[0..21]	[390..431]
gi\|169779902 - gi\|169779902\|ref\|XP_001824415.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83773155 - gi\|83773155\|dbj\|BAE63282.1\| unnamed protein product [Aspergillus oryzae]	270.0	[0..3]	[379..475]
gi\|34391866 - gi\|34391866\|gb\|AAO72737.1\| trehalose-6-phosphate phosphatase [Emericella nidulans]	267.0	[0..3]	[338..506]
gi\|90307062, gi\|... - gi\|90307062\|gb\|EAS36693.1\| trehalose-phosphatase [Coccidioides immitis RS], gi\|119195345\|ref\|XP_0012...	266.0	[0..6]	[379..536]

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Predicted Domain #1

Region A:
Residues: [1-125]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKLGPVTID PRRHDAVLFD TTLDATQELV RQLQEVGVGT GVFGSGLDVP IVAAGRLAVR  60
   61 PGRCVVVSAH SAGVTAARES GFALIIGVDR TGCRDALRRD GADTVVTDLS EVSVRTGDRR 120
  121 MSQLP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.09691
Match:	1uqtA
Description:	Trehalose-6-phosphate from E. coli bound with UDP-2-fluoro glucose.
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [126-391]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DALQALGLAD GLVARQPAVF FDFDGTLSDI VEDPDAAWLA PGALEALQKL AARCPIAVLS  60
   61 GRDLADVTQR VGLPGIWYAG SHGFELTAPD GTHHQNDAAA AAIPVLKQAA AELRQQLGPF 120
  121 PGVVVEHKRF GVAVHYRNAA RDRVGEVAAA VRTAEQRHAL RVTTGREVIE LRPDVDWDKG 180
  181 KTLLWVLDHL PHSGSAPLVP IYLGDDITDE DAFDVVGPHG VPIVVRHTDD GDRATAALFA 240
  241 LDSPARVAEF TDRLARQLRE APLRAT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.39794
Match:	1rkqA
Description:	Crystal structure of NYSGRC target T1436: A Hypothetical protein yidA.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.92340854382984	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: