YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|254825375
Organism:	Listeria monocytogenes FSL J1-194
Length:	482 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|254825375.

Description	E-value	Query Range	Subject Range
CLS_LISIN - Cardiolipin synthase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=cls PE=3 SV=1 CLS_LISIN - Cardiolipin synthase OS=Listeria innocua GN=cls PE=3 SV=1	407.0	[0..15]	[482..15]
gi\|221315944 - gi\|221315944\|ref\|ZP_03597749.1\| hypothetical protein BsubsN3_19697 [Bacillus subtilis subsp. subtili... CLSA_BACSU - Major cardiolipin synthase ClsA OS=Bacillus subtilis (strain 168) GN=clsA PE=1 SV=2 gi\|221320856 - gi\|221320856\|ref\|ZP_03602150.1\| hypothetical protein BsubsJ_19645 [Bacillus subtilis subsp. subtilis... CLS2_BACSU - Probable cardiolipin synthase 2 OS=Bacillus subtilis GN=ywnE PE=3 SV=2 gi\|221325141 - gi\|221325141\|ref\|ZP_03606435.1\| hypothetical protein BsubsS_19811 [Bacillus subtilis subsp. subtilis...	405.0	[0..1]	[482..1]
gi\|68446672, gi\|... - gi\|70725948\|ref\|YP_252862.1\| hypothetical protein SH0947 [Staphylococcus haemolyticus JCSC1435], gi\|...	400.0	[0..14]	[482..26]
CLS_OCEIH - Cardiolipin synthase OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)... CLS_OCEIH - Cardiolipin synthase OS=Oceanobacillus iheyensis GN=cls PE=3 SV=1	395.0	[0..1]	[482..1]
gi\|56963585, gi\|... - gi\|56963585\|ref\|YP_175316.1\| cardiolipin synthetase [Bacillus clausii KSM-K16], gi\|56909828\|dbj\|BAD6...	392.0	[0..5]	[482..11]
gi\|52350075, gi\|... - gi\|52787573\|ref\|YP_093402.1\| YwnE [Bacillus licheniformis ATCC 14580], gi\|52350075\|gb\|AAU42709.1\| Yw...	392.0	[0..2]	[482..8]
gi\|89099694, gi\|... - gi\|89099694\|ref\|ZP_01172568.1\| YwnE [Bacillus sp. NRRL B-14911], gi\|89085637\|gb\|EAR64764.1\| YwnE [Ba...	391.0	[0..1]	[482..1]
gi\|49244605, gi\|... - gi\|49486162\|ref\|YP_043383.1\| putative cardiolipin synthase [Staphylococcus aureus subsp. aureus MSSA...	386.0	[0..2]	[482..11]
gi\|251814239, gi... - gi\|251814239\|ref\|ZP_04828712.1\| cardiolipin synthetase [Staphylococcus aureus subsp. aureus TCH70], ... gi\|21282934, gi\|... - gi\|21282934\|ref\|NP_646022.1\| hypothetical protein MW1205 [Staphylococcus aureus subsp. aureus MW2], ...	386.0	[0..2]	[482..23]
CLS1_STAES - Cardiolipin synthase 1 OS=Staphylococcus epidermidis (strain ATCC 12228) GN=cls1 PE=3 SV=1 gi\|251810750, gi... - gi\|251810750\|ref\|ZP_04825223.1\| cardiolipin synthetase [Staphylococcus epidermidis BCM-HMP0060], gi\|... CLS1_STAEP - (Q8CPD8) Cardiolipin synthetase 1 (EC 2.7.8.-) (Cardiolipin synthase 1) (CL synthase 1)	385.0	[0..2]	[482..8]

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Predicted Domain #1

Region A:
Residues: [1-482]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLLAYLLVI LLILNVFFAA VTVFLERRDT SATWAWLLVL TFVPIFGFII YLIFGRKLSG  60
   61 KKIFDWKGQE KIGIQESTAN QIEMIRQKEF PFSDPNVKKH RDLIYLLLVN DGAILTQDNE 120
  121 VELFVDGHEK FDALIADIEK AKDHIHLIYY IFHSDELGNR LMRVLERKAA EGLNVKIIYD 180
  181 AMGSRTTKKS FFRTFQKNGG LVRPFFPSKL PLINFRLNYR NHRKLAIIDG DVGYIGGFNI 240
  241 GDEYLGASKK FGYWRDTHLR VHGKAVYAMQ TRFIMDWNSA SSTHKIDYKA RYFPTFHGKG 300
  301 HTSMQIVSSG PDSEWQQIKN GYIKMINAAK KTIYLQSPYF IPDASLLEAI KIAALSGVDV 360
  361 RVMIPNKPDH AFVYRATTNY AGELMETGAK IFIYDNGFIH AKTLVVDGEI ASVGTANMDF 420
  421 RSFRLNFEVN AFIYEKQMVQ KLEDAFLEDI LKSYQLTPEL YAKRSLWIKF KEAVSRLLSP 480
  481 IL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.0
Match:	1xdoA
Description:	Crystal Structure of Escherichia coli Polyphosphate Kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoric diester hydrolase activity	1.55477881010087	bayes_pls_golite062009
catalytic activity	1.29236214516383	bayes_pls_golite062009
binding	0.66572565048579	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.486367378916393	bayes_pls_golite062009
protein binding	0.162885453822356	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: