YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|253315978
Organism:	Staphylococcus aureus subsp. aureus str. CF-Marseille
Length:	241 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|253315978.

Description	E-value	Query Range	Subject Range
MENG_STAAB - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) GN=menG...	234.0	[0..1]	[241..1]
MENG_STAAR - Demethylmenaquinone methyltransferase OS=Staphylococcus aureus (strain MRSA252) GN=menG PE=3 SV=1 gi\|227558277, gi... - gi\|227558277\|ref\|ZP_03988324.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Staphylococcu...	230.0	[0..1]	[241..1]
MENG_STAES - Demethylmenaquinone methyltransferase OS=Staphylococcus epidermidis (strain ATCC 12228) GN=menG PE=3... UBIE_STAEP - (Q8CSH9) Menaquinone biosynthesis methyltransferase ubiE (EC 2.1.1.-) MENG_STAEQ - Demethylmenaquinone methyltransferase OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) GN=m...	220.0	[0..1]	[241..1]
gi\|218321183, gi... - gi\|218708164\|ref\|YP_002415785.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splen... gi\|85835662, gi\|... - gi\|86146605\|ref\|ZP_01064927.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio sp. MED...	214.0	[0..6]	[233..33]
MENG_STAHJ - Demethylmenaquinone methyltransferase OS=Staphylococcus haemolyticus (strain JCSC1435) GN=menG PE=3 ...	214.0	[0..1]	[239..1]
gi\|84386296, gi\|... - gi\|84386296\|ref\|ZP_00989324.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splendi...	213.0	[0..6]	[233..33]
UBIE_VIBVU - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio vulnificus (strain CMCP6) GN=... UBIE_VIBVY - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio vulnificus (strain YJ016) GN=... UBIE_VIBVU - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio vulnificus GN=ubiE PE=3 SV=1	212.0	[0..5]	[233..28]
gi\|149746384, gi... - gi\|153840045\|ref\|ZP_01992712.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Vibrio p... UBIE_VIBPA - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio parahaemolyticus serotype O3:... UBIE_VIBPA - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio parahaemolyticus GN=ubiE PE=3 S...	212.0	[0..5]	[233..27]
UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... UBIE_VIBCM - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|229508366, gi... - gi\|229508366\|ref\|ZP_04397870.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229346129, gi... - gi\|229517066\|ref\|ZP_04406512.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229520118, gi... - gi\|229520118\|ref\|ZP_04409546.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229527169, gi... - gi\|229527169\|ref\|ZP_04416563.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229369296, gi... - gi\|229606641\|ref\|YP_002877289.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vi... gi\|121587669, gi... - gi\|121587669\|ref\|ZP_01677432.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|124115249, gi... - gi\|153214643\|ref\|ZP_01949519.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|254851469, gi... - gi\|75829374\|ref\|ZP_00758679.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153222877, gi... - gi\|153222877\|ref\|ZP_01953501.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153801700, gi... - gi\|153801700\|ref\|ZP_01956286.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|116216422, gi... - gi\|75823221\|ref\|ZP_00752740.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153818222, gi... - gi\|153818222\|ref\|ZP_01970889.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBC3 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|126520347, gi... - gi\|229508952\|ref\|ZP_04398442.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|121727801, gi... - gi\|75816414\|ref\|ZP_00746885.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|254291829, gi... - gi\|254291829\|ref\|ZP_04962613.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153829106, gi... - gi\|153829106\|ref\|ZP_01981773.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio cholerae GN=ubiE PE=3 SV=1 gi\|149739586, gi... - gi\|153826648\|ref\|ZP_01979315.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...	211.0	[0..3]	[233..28]
gi\|91224931, gi\|... - gi\|91224931\|ref\|ZP_01260190.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio alginol...	211.0	[0..6]	[233..28]

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Predicted Domain #1

Region A:
Residues: [1-241]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADNKANKEQ VHRVFQNISK KYDRLNNIIS FEQHKVWRKR VMKDMGVRKG TKALDVCCGT  60
   61 GDWTIALSKA VGPTGEVTGI DFSENMLEVG KEKTASMENV KLVHGDAMEL PFEDNSFDYV 120
  121 TIGFGLRNVP DYLVALKEMN RVLKPGGMVV CLETSQPTLP VFKQMYALYF KFVMPIFGKL 180
  181 FAKSKEEYEW LQQSTFNFPG KEELKRMFEE AGFINVRVRS FTGGVAAMHL GYKEKDNTKG 240
  241 D

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.69897
Match:	1kywA
Description:	Caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.62377578202456	bayes_pls_golite062009
transferase activity	1.27388514102581	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.11446137064593	bayes_pls_golite062009
methyltransferase activity	1.0967819849268	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.495483488913306	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: