YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|253321141, gi...
Organism:	Mycobacterium tuberculosis KZN 1435
Length:	165 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|253321141, gi....

Description	E-value	Query Range	Subject Range
gi\|13880961, gi\|... - gi\|15840768\|ref\|NP_335805.1\| methylated-DNA--protein-cysteine methyltransferase [Mycobacterium tuber...	224.0	[0..1]	[165..9]
OGT_MYCPA - Methylated-DNA--protein-cysteine methyltransferase OS=Mycobacterium paratuberculosis GN=ogt PE=3 SV=... gi\|118462974, gi... - gi\|118462974\|ref\|YP_880772.1\| methylated-DNA--protein-cysteine methyltransferase [Mycobacterium aviu... OGT_MYCPA - Methylated-DNA--protein-cysteine methyltransferase OS=Mycobacterium paratuberculosis (strain ATCC BA...	216.0	[0..1]	[165..1]
OGT_METAC - Methylated-DNA--protein-cysteine methyltransferase OS=Methanosarcina acetivorans GN=ogt PE=3 SV=1 OGT_METAC - Methylated-DNA--protein-cysteine methyltransferase OS=Methanosarcina acetivorans (strain ATCC 35395 ...	212.0	[0..2]	[154..1]
OGT_MYCLE - Methylated-DNA--protein-cysteine methyltransferase OS=Mycobacterium leprae GN=ogt PE=3 SV=1 OGT_MYCLE - Methylated-DNA--protein-cysteine methyltransferase OS=Mycobacterium leprae (strain TN) GN=ogt PE=3 S... gi\|221230059, gi... - gi\|221230059\|ref\|YP_002503475.1\| putative methylated-DNA-protein-cysteine methyltransferase [Mycobac...	212.0	[0..1]	[165..1]
gi\|27359161, gi\|... - gi\|27367589\|ref\|NP_763116.1\| methylated DNA-protein cysteine methyltransferase [Vibrio vulnificus CM...	210.0	[0..1]	[153..1]
gi\|88780111, gi\|... - gi\|88797242\|ref\|ZP_01112832.1\| methylated-DNA-protein-cysteine S-methyltransferase [Reinekea sp. MED...	208.0	[0..1]	[154..1]
gi\|37200236, gi\|... - gi\|37675697\|ref\|NP_936093.1\| methylated DNA-protein cysteine methyltransferase [Vibrio vulnificus YJ...	208.0	[0..1]	[153..1]
gi\|119869975, gi... - gi\|92914585\|ref\|ZP_01283211.1\| Methylated-DNA--(protein)-cysteine S-methyltransferase [Mycobacterium... gi\|108800835, gi... - gi\|108800835\|ref\|YP_641032.1\| methylated-DNA--protein-cysteine methyltransferase [Mycobacterium sp. ...	208.0	[0..2]	[165..3]
OGT_METBF - Methylated-DNA--protein-cysteine methyltransferase OS=Methanosarcina barkeri (strain Fusaro / DSM 80...	207.0	[0..2]	[158..1]
gi\|90200145, gi\|... - gi\|90203266\|ref\|ZP_01205912.1\| Methylated-DNA--(protein)-cysteine S-methyltransferase [Mycobacterium...	207.0	[0..2]	[165..4]

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Predicted Domain #1

Region A:
Residues: [1-165]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIHYRTIDSP IGPLTLAGHG SVLTNLRMLE QTYEPSRTHW TPDPGAFSGA VDQLNAYFAG  60
   61 ELTEFDVELD LRGTDFQQRV WKALLTIPYG ETRSYGEIAD QIGAPGAARA VGLANGHNPI 120
  121 AIIVPCHRVI GASGKLTGYG GGINRKRALL ELEKSRAPAD LTLFD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.0
Match:	1sfeA
Description:	ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE FROM ESCHERICHIA COLI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methylated-DNA-[protein]-cysteine S-methyltransferase activity	3.9938943760254	bayes_pls_golite062009
S-methyltransferase activity	2.96219931728042	bayes_pls_golite062009
catalytic activity	2.27882522649583	bayes_pls_golite062009
methyltransferase activity	1.63681159093596	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.6341981985862	bayes_pls_golite062009
transferase activity	1.42883081715544	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: