YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|229690617, gi...
Organism:	Yersinia pestis biovar Orientalis str. India 195
Length:	130 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|229690617, gi....

Description	E-value	Query Range	Subject Range
FRDC_ECOK1 - Fumarate reductase subunit C OS=Escherichia coli O1:K1 / APEC GN=frdC PE=3 SV=1 gi\|124531204, gi... - gi\|124531204\|ref\|ZP_01701549.1\| fumarate reductase, subunit C [Escherichia coli B], gi\|124498723\|gb\|... FRDC_ECOLC - Fumarate reductase subunit C OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=frdC PE=3... FRDC_ECOL6 - Fumarate reductase subunit C OS=Escherichia coli O6 GN=frdC PE=3 SV=1 EG10332 - fumarate reductase (anaerobic), membrane anchor subunit / Fumarate reductase membrane anchor polypep... FRDC_ECOUT - Fumarate reductase subunit C OS=Escherichia coli (strain UTI89 / UPEC) GN=frdC PE=3 SV=1 gi\|15834387, gi\|... - gi\|15834387\|ref\|NP_313160.1\| fumarate reductase subunit C [Escherichia coli O157:H7 str. Sakai], gi\|... FRDC_ECOL5 - Fumarate reductase subunit C OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=frdC PE=3 SV=1 FRDC_SHIF8 - Fumarate reductase subunit C OS=Shigella flexneri serotype 5b (strain 8401) GN=frdC PE=3 SV=1 sp\|B7UPX4\|FRDC_ECO27 - Fumarate reductase subunit C OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=frdC PE=3 SV=1 FRDC_ECOL6 - Fumarate reductase subunit C OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=frdC ... FRDC_ECO57 - Fumarate reductase subunit C OS=Escherichia coli O157:H7 GN=frdC PE=3 SV=1 EG10332 - fumarate reductase (anaerobic), membrane anchor subunit / Fumarate reductase membrane anchor polypep... gi\|15804746, gi\|... - gi\|15804746\|ref\|NP_290787.1\| fumarate reductase subunit C [Escherichia coli O157:H7 EDL933], gi\|1251... gi\|75238680, gi\|... - gi\|75238680\|ref\|ZP_00722669.1\| COG3029: Fumarate reductase subunit C [Escherichia coli E110019], gi\|... gi\|190906368, gi... - gi\|75239121\|ref\|ZP_00723101.1\| COG3029: Fumarate reductase subunit C [Escherichia coli F11], gi\|1911... gi\|188017465, gi... - gi\|188017465\|gb\|EDU55587.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 str. ... gi\|75209853, gi\|... - gi\|75209853\|ref\|ZP_00710051.1\| COG3029: Fumarate reductase subunit C [Escherichia coli B171], gi\|194... gi\|168755342, gi... - gi\|189357504\|gb\|EDU75923.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 str. ... gi\|191165653, gi... - gi\|75231251\|ref\|ZP_00717658.1\| COG3029: Fumarate reductase subunit C [Escherichia coli B7A], gi\|1911... gi\|189368641, gi... - gi\|189368641\|gb\|EDU87057.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 str. ... FRDC_SHISS - Fumarate reductase subunit C OS=Shigella sonnei (strain Ss046) GN=frdC PE=3 SV=1 gi\|168766432, gi... - gi\|189364102\|gb\|EDU82521.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 str. ... gi\|89110875, gi\|... - gi\|89110875\|ref\|AP_004655.1\| fumarate reductase (anaerobic), membrane anchor subunit [Escherichia co... gi\|187769838, gi... - gi\|187769838\|gb\|EDU33682.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 str. ... gi\|193065726, gi... - gi\|75256209\|ref\|ZP_00727897.1\| COG3029: Fumarate reductase subunit C [Escherichia coli E22], gi\|1930... gi\|189001750, gi... - gi\|189001750\|gb\|EDU70736.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 str. ... gi\|188487858, gi... - gi\|75514913\|ref\|ZP_00737142.1\| COG3029: Fumarate reductase subunit C [Escherichia coli 53638], gi\|18... gi\|168784790, gi... - gi\|189375056\|gb\|EDU93472.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 str. ... FRDC_ECOLI - Fumarate reductase subunit C (Fumarate reductase 15 kDa hydrophobic protein) - Escherichia coli gi\|237703821, gi... - gi\|237703821\|ref\|ZP_04534302.1\| fumarate reductase subunit C [Escherichia sp. 3_2_53FAA], gi\|2269017... FRDC_ECOBW - Fumarate reductase subunit C OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=frdC PE=3 SV=1 gi\|251787407, gi... - gi\|251787407\|ref\|YP_003001711.1\| hypothetical protein B21_03986 [Escherichia coli BL21], gi\|24237968... FRDC_ECO24 - Fumarate reductase subunit C OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=frdC PE=3 SV=1 gi\|253980143, gi... - gi\|254290836\|ref\|YP_003056584.1\| fumarate reductase subunit C [Escherichia coli BL21(DE3)], gi\|25398... FRDC_ECOHS - Fumarate reductase subunit C OS=Escherichia coli O9:H4 (strain HS) GN=frdC PE=3 SV=1 gi\|226840274, gi... - gi\|254037168\|ref\|ZP_04871245.1\| fumarate reductase subunit C [Escherichia sp. 1_1_43], gi\|226840274\|... gi\|194423847, gi... - gi\|83587275\|ref\|ZP_00925904.1\| COG3029: Fumarate reductase subunit C [Escherichia coli 101-1], gi\|19... gi\|253975987, gi... - gi\|254164086\|ref\|YP_003047194.1\| fumarate reductase subunit C [Escherichia coli B str. REL606], gi\|2... FRDC_SHIB3 - Fumarate reductase subunit C OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=frdC PE=... gi\|254796176, gi... - gi\|254796176\|ref\|YP_003081013.1\| fumarate reductase (anaerobic), membrane anchor subunit [Escherichi... FRDC_ECOSE - Fumarate reductase subunit C OS=Escherichia coli (strain SE11) GN=frdC PE=3 SV=1 FRDC_ECO27 - Fumarate reductase subunit C OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=frdC PE=3 SV=1 gi\|217322793, gi... - gi\|217326572\|ref\|ZP_03442656.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 s... FRDC_ESCF3 - Fumarate reductase subunit C OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)... FRDC_ECO8A - Fumarate reductase subunit C OS=Escherichia coli O8 (strain IAI1) GN=frdC PE=3 SV=1 FRDC_ECO45 - Fumarate reductase subunit C OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=frdC PE=3 SV=1 FRDC_ECO55 - Fumarate reductase subunit C OS=Escherichia coli (strain 55989 / EAEC) GN=frdC PE=3 SV=1 FRDC_ECO7I - Fumarate reductase subunit C OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=frdC PE=3 SV=1 gi\|189375640, gi... - gi\|189375640\|gb\|EDU94056.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 str. ... FRDC_ECODH - Fumarate reductase subunit C OS=Escherichia coli (strain K12 / DH10B) GN=frdC PE=3 SV=1 FRDC_ECOSM - Fumarate reductase subunit C OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=frdC PE=3 SV=1 gi\|195935946 - gi\|195935946\|ref\|ZP_03081328.1\| fumarate reductase subunit C [Escherichia coli O157:H7 str. EC4024] gi\|208725583, gi... - gi\|208805782\|ref\|ZP_03248119.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 s... gi\|208813429, gi... - gi\|208813429\|ref\|ZP_03254758.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 s... gi\|208818295, gi... - gi\|208818295\|ref\|ZP_03258615.1\| fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 s... FRDC_ECO5E - Fumarate reductase subunit C OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=frdC PE=3 SV=1	8.0E-48	[1..129]	[1..129]
FRDC_SHIBS - Fumarate reductase subunit C OS=Shigella boydii serotype 4 (strain Sb227) GN=frdC PE=3 SV=1	1.0E-47	[1..129]	[1..129]
FRDC_SHIDS - Fumarate reductase subunit C OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=frdC PE=3 SV=1	2.0E-47	[1..129]	[1..129]
gi\|171849106, gi... - gi\|90108812\|pdb\|2B76\|O Chain O, E. Coli Quinol Fumarate Reductase Frda E49q Mutation, gi\|90108808\|pd...	3.0E-47	[2..129]	[1..128]
gi\|24054836, gi\|... - gi\|24115511\|ref\|NP_710021.1\| fumarate reductase subunit C [Shigella flexneri 2a str. 301], gi\|240548... FRDC_SHIFL - Fumarate reductase subunit C OS=Shigella flexneri GN=frdC PE=3 SV=1 gi\|30043793, gi\|... - gi\|30065529\|ref\|NP_839700.1\| fumarate reductase subunit C [Shigella flexneri 2a str. 2457T], gi\|3004...	2.0E-46	[1..129]	[1..129]
gi\|197263825, gi... - gi\|197263825\|ref\|ZP_03163899.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp.... FRDC_SALA4 - Fumarate reductase subunit C OS=Salmonella agona (strain SL483) GN=frdC PE=3 SV=1 FRDC_SALSV - Fumarate reductase subunit C OS=Salmonella schwarzengrund (strain CVM19633) GN=frdC PE=3 SV=1 gi\|194472926, gi... - gi\|194472926\|ref\|ZP_03078910.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp.... FRDC_SALG2 - Fumarate reductase subunit C OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=frdC PE=3 SV=1 gi\|204323382, gi... - gi\|204926717\|ref\|ZP_03217919.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp.... gi\|200387160, gi... - gi\|200387160\|ref\|ZP_03213772.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp.... FRDC_SALPK - Fumarate reductase subunit C OS=Salmonella paratyphi A (strain AKU_12601) GN=frdC PE=3 SV=1 gi\|205336323, gi... - gi\|205336323\|gb\|EDZ23087.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp. ent... gi\|197289959, gi... - gi\|197289959\|gb\|EDY29318.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp. ent... gi\|205334243, gi... - gi\|205334243\|gb\|EDZ21007.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp. ent... gi\|167994777, gi... - gi\|205327404\|gb\|EDZ14168.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp. ent... FRDC_SALNS - Fumarate reductase subunit C OS=Salmonella newport (strain SL254) GN=frdC PE=3 SV=1 gi\|205341110, gi... - gi\|205341110\|gb\|EDZ27874.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp. en... FRDC_SALTY - Fumarate reductase subunit C OS=Salmonella typhimurium GN=frdC PE=3 SV=1 FRDC_SALTY - Fumarate reductase subunit C OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=frdC... gi\|195630648, gi... - gi\|195630648\|gb\|EDX49260.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp. ent... FRDC_SALTI - Fumarate reductase subunit C OS=Salmonella typhi GN=frdC PE=3 SV=1 gi\|168263305, gi... - gi\|205347966\|gb\|EDZ34597.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp. ent... FRDC_SALCH - Fumarate reductase subunit C OS=Salmonella choleraesuis GN=frdC PE=3 SV=1 gi\|213585254 - gi\|213585254\|ref\|ZP_03367080.1\| fumarate reductase subunit C [Salmonella enterica subsp. enterica se... FRDC_SALCH - Fumarate reductase subunit C OS=Salmonella choleraesuis GN=frdC PE=3 SV=1 gi\|213428691 - gi\|213428691\|ref\|ZP_03361441.1\| fumarate reductase subunit C [Salmonella enterica subsp. enterica se... gi\|213052297 - gi\|213052297\|ref\|ZP_03345175.1\| fumarate reductase subunit C [Salmonella enterica subsp. enterica se... FRDC_SALEP - Fumarate reductase subunit C OS=Salmonella enteritidis PT4 (strain P125109) GN=frdC PE=3 SV=1 gi\|238912806 - gi\|238912806\|ref\|ZP_04656643.1\| fumarate reductase subunit C [Salmonella enterica subsp. enterica se... gi\|214003376 - gi\|214003376\|ref\|ZP_03414111.1\| fumarate reductase subunit C [Salmonella enterica subsp. enterica se... gi\|213852160 - gi\|213852160\|ref\|ZP_03381692.1\| fumarate reductase subunit C [Salmonella enterica subsp. enterica se... FRDC_SALPB - Fumarate reductase subunit C OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=frdC PE=3 SV... FRDC_SALPB - Fumarate reductase subunit C OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=frdC PE=3 SV... gi\|213646924 - gi\|213646924\|ref\|ZP_03376977.1\| fumarate reductase subunit C [Salmonella enterica subsp. enterica se... FRDC_SALPA - Fumarate reductase subunit C OS=Salmonella paratyphi A GN=frdC PE=3 SV=1 gi\|213621850 - gi\|213621850\|ref\|ZP_03374633.1\| fumarate reductase subunit C [Salmonella enterica subsp. enterica se... FRDC_SALTY - Fumarate reductase subunit C OS=Salmonella typhimurium GN=frdC PE=3 SV=1 FRDC_SALTI - Fumarate reductase subunit C OS=Salmonella typhi GN=frdC PE=3 SV=1 gi\|16763163 - gi\|16763163\|ref\|NP_458780.1\| fumarate reductase subunit C [Salmonella enterica subsp. enterica serov... gi\|29140281, gi\|... - gi\|29144642\|ref\|NP_807984.1\| fumarate reductase subunit C [Salmonella enterica subsp. enterica serov... gi\|205322010, gi... - gi\|205322010\|gb\|EDZ09849.1\| fumarate reductase, cytochrome b subunit [Salmonella enterica subsp. ent... lcl\|NC_016856.1_... - [gene=frdC] [protein=fumarate reductase subunit C] [protein_id=YP_005240655.1] [location=complement(... FRDC_SALCH - Fumarate reductase subunit C OS=Salmonella choleraesuis (strain SC-B67) GN=frdC PE=3 SV=1 FRDC_SALPA - Fumarate reductase subunit C OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=frdC PE=3 SV=1	2.0E-45	[1..130]	[1..130]
FRDC_PROVU - Fumarate reductase subunit C OS=Proteus vulgaris GN=frdC PE=3 SV=2	1.0E-44	[1..130]	[1..130]
FRDC_YERPG - Fumarate reductase subunit C OS=Yersinia pestis bv. Antiqua (strain Angola) GN=frdC PE=3 SV=1	1.0E-44	[1..130]	[1..130]
gi\|77977159, gi\|... - gi\|77977159\|ref\|ZP_00832616.1\| COG3029: Fumarate reductase subunit C [Yersinia intermedia ATCC 29909...	9.0E-44	[1..130]	[1..130]

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Predicted Domain #1

Region A:
Residues: [1-130]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTKRKAYVR TMAPNWWQQL GFYRFYMLRE GTSIPAVWFS VLLIYGVFAL KSGPAGWEGF  60
   61 VSFLQNPLVL FLNILTLFAA LLHTKTWFEL APKAVNIIVK SEKMGPEPMI KALWVVTVVA 120
  121 SAIILAVALL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.69897
Match:	1kf6C
Description:	Fumarate reductase subunit FrdC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
succinate dehydrogenase activity	3.77307162030081	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	2.15706429275351	bayes_pls_golite062009
oxidoreductase activity	2.006262138179	bayes_pls_golite062009
electron carrier activity	1.35460962236208	bayes_pls_golite062009
catalytic activity	1.34226547326392	bayes_pls_golite062009
binding	0.407887533459531	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: