YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|253316427
Organism:	Staphylococcus aureus subsp. aureus str. CF-Marseille
Length:	288 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|253316427.

Description	E-value	Query Range	Subject Range
gi\|227558490, gi... - gi\|227558490\|ref\|ZP_03988537.1\| pyruvate ferredoxin dehydrogenase beta subunit [Staphylococcus aureu... gi\|227851346, gi... - gi\|227900283\|ref\|ZP_04018088.1\| pyruvate ferredoxin dehydrogenase beta subunit [Staphylococcus aureu... gi\|49483453, gi\|... - gi\|49483453\|ref\|YP_040677.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Staphylococcus a...	238.0	[0..1]	[288..1]
gi\|163941461, gi... - gi\|89208771\|ref\|ZP_01187259.1\| 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisova...	237.0	[0..1]	[288..1]
gi\|29897421, gi\|... - gi\|30021865\|ref\|NP_833496.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus cereus ... gi\|206732428, gi... - gi\|206972615\|ref\|ZP_03233557.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus ... gi\|218163359, gi... - gi\|218235402\|ref\|YP_002368576.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus... gi\|218898873, gi... - gi\|218898873\|ref\|YP_002447284.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus...	237.0	[0..1]	[288..1]
gi\|87202558, gi\|... - gi\|88195000\|ref\|YP_499800.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Staphylococcus a...	237.0	[0..1]	[288..1]
gi\|68447348, gi\|... - gi\|70726624\|ref\|YP_253538.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Staphylococcus h...	236.0	[0..1]	[288..1]
gi\|165872417, gi... - gi\|165872417\|ref\|ZP_02217052.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus ... gi\|167635848, gi... - gi\|167635848\|ref\|ZP_02394157.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus ... gi\|167512265, gi... - gi\|167639864\|ref\|ZP_02398133.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus ... gi\|170128315, gi... - gi\|170706897\|ref\|ZP_02897355.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus ... gi\|177652013, gi... - gi\|177652013\|ref\|ZP_02934559.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus ... gi\|190568490, gi... - gi\|190568490\|ref\|ZP_03021397.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus ... gi\|196034284, gi... - gi\|196034284\|ref\|ZP_03101694.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus ... gi\|254759375 - gi\|254759375\|ref\|ZP_05211400.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus anth... gi\|254751057 - gi\|254751057\|ref\|ZP_05203096.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus anth... gi\|254739661 - gi\|254739661\|ref\|ZP_05197355.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus anth... gi\|254735813 - gi\|254735813\|ref\|ZP_05193519.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus anth... gi\|254722039 - gi\|254722039\|ref\|ZP_05183828.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus anth... gi\|229604718, gi... - gi\|229604718\|ref\|YP_002868015.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus... gi\|196030738, gi... - gi\|196038330\|ref\|ZP_03105639.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus ... gi\|227002616, gi... - gi\|227813319\|ref\|YP_002813328.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus... gi\|196044462, gi... - gi\|196044462\|ref\|ZP_03111697.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus ... gi\|225865754, gi... - gi\|225865754\|ref\|YP_002751132.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus... gi\|206977912, gi... - gi\|206977912\|ref\|ZP_03238800.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus ... gi\|217064430, gi... - gi\|217961194\|ref\|YP_002339762.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus... gi\|218904901, gi... - gi\|218904901\|ref\|YP_002452735.1\| putative pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus... gi\|221241277, gi... - gi\|222097219\|ref\|YP_002531276.1\| pyruvate ferredoxin oxidoreductase, beta subunit [Bacillus cereus Q... gi\|47568278, gi\|... - gi\|47568278\|ref\|ZP_00238981.1\| pyruvate synthase subunit porB [Bacillus cereus G9241], gi\|47555106\|g... gi\|51975184, gi\|... - gi\|52141715\|ref\|YP_085114.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus cereus ... gi\|49186623, gi\|... - gi\|49186623\|ref\|YP_029875.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus anthrac... gi\|49481608, gi\|... - gi\|49481608\|ref\|YP_037834.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus thuring... gi\|42738785, gi\|... - gi\|42782858\|ref\|NP_980105.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus cereus ... gi\|47504348, gi\|... - gi\|47529200\|ref\|YP_020549.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus anthrac... gi\|65321099, gi\|... - gi\|65321099\|ref\|ZP_00394058.1\| COG1013: Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:fer... gi\|30258423, gi\|... - gi\|30263779\|ref\|NP_846156.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus anthrac... gi\|118478994, gi... - gi\|118478994\|ref\|YP_896145.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus thurin...	234.0	[0..1]	[288..1]
gi\|221089890, gi... - gi\|221089890\|ref\|ZP_03559394.1\| pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit [Geobaci... gi\|56419837, gi\|... - gi\|56419837\|ref\|YP_147155.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Geobacillus kaus... gi\|229328394, gi... - gi\|229500714\|ref\|ZP_04394360.1\| pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit [Geobaci...	234.0	[0..1]	[288..1]
gi\|57866795, gi\|... - gi\|57866795\|ref\|YP_188439.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Staphylococcus e... gi\|251805881, gi... - gi\|251810721\|ref\|ZP_04825194.1\| pyruvate ferredoxin dehydrogenase beta subunit [Staphylococcus epide... gi\|27315431, gi\|... - gi\|27467886\|ref\|NP_764523.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Staphylococcus e...	233.0	[0..1]	[288..1]
gi\|10174993, gi\|... - gi\|15614936\|ref\|NP_243239.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Bacillus halodur... gi\|25494511 - pir\|\|E83946 pyruvate synthase beta subunit BH2373 [imported] - Bacillus halodurans (strain C-125)	231.0	[0..1]	[288..1]
gi\|89149392, gi\|... - gi\|89202597\|ref\|ZP_01181313.1\| 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisova...	230.0	[0..1]	[288..1]

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Predicted Domain #1

Region A:
Residues: [1-288]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATFKDFRNN VKPNWCPGCG DFSVQAAIQK AAANIGLEPE EVAIITGIGC SGRLSGYINS  60
   61 YGVHSIHGRA LPLAQGVKMA NKDLTVIASG GDGDGYAIGM GHTIHALRRN MNMTYIVMDN 120
  121 QIYGLTKGQT SPSSAVGFVT KTTPKGNIEK NVAPLELALS SGATFVAQGF SSDIKGLTKL 180
  181 IEDAINHDGF SFVNVFSPCV TYNKINTYDW FKEHLTSVDD IENYDSTDKQ LATKTVIEHE 240
  241 SLVTGIVYQD KETPSYESQI KELDDTPLAK RDIKITEDTF NALTEQFI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.522879
Match:	1w88A
Description:	The crystal structure of pyruvate deydrogenase E1(D180N,E183Q) bound to the peripheral subunit binding domain of E2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.62581591393304	bayes_pls_golite062009
oxidoreductase activity	1.76278237247276	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	1.33446932713773	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: