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View Structure Prediction Details

Protein: HBA_DANRE
Organism: Danio rerio
Length: 143 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HBA_DANRE.

Description E-value Query
Range		 Subject
Range
HBA_CANLA - Hemoglobin subunit alpha OS=Canis latrans GN=HBA PE=1 SV=2
 176.0 [0..1] [143..1]
HBA_AILME - Hemoglobin subunit alpha OS=Ailuropoda melanoleuca GN=HBA PE=1 SV=2
 175.0 [0..1] [143..1]
HBA_AILFU - Hemoglobin subunit alpha OS=Ailurus fulgens GN=HBA PE=1 SV=2
 175.0 [0..1] [143..1]
gi|73988393 - gi|73988393|ref|XP_542374.2| PREDICTED: similar to Hemoglobin epsilon chain [Canis familiaris]
 174.0 [0..1] [142..46]
gi|70191 - gi|70191|pir||HADG2 hemoglobin alpha-II chain - dog
HBA_CHRBR - Hemoglobin subunit alpha OS=Chrysocyon brachyurus GN=HBA PE=1 SV=1
gi|116666788, gi... - gi|116666788|pdb|2B7H|C Chain C, Hemoglobin From Cerdocyon Thous, A Canidae From Brazil, At 2.2 Angs...
HBA_CANLA - (P60530) Hemoglobin subunit alpha (Hemoglobin alpha chain) (Alpha-globin)
 174.0 [0..2] [143..1]
HBA_VULVU - Hemoglobin subunit alpha OS=Vulpes vulpes GN=HBA PE=1 SV=1
 174.0 [0..2] [143..1]
HBA_PIPAB - Hemoglobin subunit alpha OS=Pipistrellus abramus GN=HBA PE=2 SV=3
 173.0 [0..1] [143..1]
HBA_PROLO - Hemoglobin subunit alpha OS=Procyon lotor GN=HBA PE=1 SV=1
 173.0 [0..2] [143..1]
HBA_NASNA - Hemoglobin subunit alpha OS=Nasua nasua GN=HBA PE=1 SV=1
gi|108153 - pir||A39020 hemoglobin alpha chain - ring-tailed coati
 173.0 [0..2] [143..1]

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Predicted Domain #1
Region A:
Residues: [1-143] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSDTDKAV VKAIWAKISP KADEIGAEAL ARMLTVYPQT KTYFSHWADL SPGSGPVKKH  60
   61 GKTIMGAVGE AISKIDDLVG GLAALSELHA FKLRVDPANF KILSHNVIVV IAMLFPADFT 120
  121 PEVHVSVDKF FNNLALALSE KYR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.69897
Match: 1la6A
Description: Hemoglobin, alpha-chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxygen transporter activity 12.7518923261978 bayes_pls_golite062009
hemoglobin binding 7.80994828423656 bayes_pls_golite062009
oxygen binding 7.60582561525971 bayes_pls_golite062009
hemoglobin alpha binding 6.6133698394882 bayes_pls_golite062009
organic acid binding 4.76461807092667 bayes_pls_golite062009
hemoglobin beta binding 3.70103281638942 bayes_pls_golite062009
transporter activity 2.30531874940611 bayes_pls_golite062009
substrate-specific transporter activity 2.13533596372692 bayes_pls_golite062009
binding 1.61998555357457 bayes_pls_golite062009
protein binding 1.50013290504406 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 0.436801914510671 bayes_pls_golite062009
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