YRC Public Data Repository - Protein Structure Prediction

Protein:	AP4A_MOUSE
Organism:	Mus musculus
Length:	147 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AP4A_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|13384960, gi\|... - ref\|NP_079815.1\| nudix (nucleoside diphosphate linked moiety X)-type motif 2 [Mus musculus], gi\|128...	116.0	[0..1]	[147..1]
ADPP_METJA - ADP-ribose pyrophosphatase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / ... ADPP_METJA - ADP-ribose pyrophosphatase OS=Methanocaldococcus jannaschii GN=nudF PE=1 SV=1	116.0	[0..10]	[141..39]
AP4A_PIG - Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] OS=Sus scrofa GN=NUDT2 PE=2 SV=3	116.0	[0..1]	[147..1]
AP4A_RAT - Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] OS=Rattus norvegicus GN=Nudt2 PE=2 SV=3	115.0	[0..1]	[147..1]
gi\|109111196 - gi\|109111196\|ref\|XP_001098004.1\| PREDICTED: nudix (nucleoside diphosphate linked moiety X)-type moti...	115.0	[0..1]	[147..1]
gi\|114624173, gi... - gi\|55633127\|ref\|XP_520541.1\| PREDICTED: nudix-type motif 2 isoform 4 [Pan troglodytes], gi\|114624176... gi\|61355400, gi\|... - gi\|61355400\|gb\|AAX41136.1\| nudix-type motif 2 [synthetic construct], gi\|60814513\|gb\|AAX36304.1\| nudi... NUDT2 - nudix (nucleoside diphosphate linked moiety X)-type motif 2	113.0	[0..1]	[147..1]
gi\|60826381, gi\|... - gi\|61365401\|gb\|AAX42702.1\| nudix-type motif 2 [synthetic construct], gi\|60826381\|gb\|AAX36755.1\| nudi...	113.0	[0..1]	[147..1]
gi\|71906713, gi\|... - gi\|71906713\|ref\|YP_284300.1\| NUDIX hydrolase [Dechloromonas aromatica RCB], gi\|71846334\|gb\|AAZ45830....	113.0	[0..1]	[140..118]
gi\|83949916, gi\|... - gi\|83949916\|ref\|ZP_00958649.1\| hydrolase, NUDIX family protein of the NudH subfamily [Roseovarius nu...	113.0	[0..1]	[145..1]

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Predicted Domain #1

Region A:
Residues: [1-147]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRACGLII FRRHLIPKMD NSTIEFLLLQ ASDGIHHWTP PKGHVDPGEN DLETALRETR  60
   61 EETGIEASQL TIIEGFRREL NYVARQKPKT VIYWLAEVKD YNVEIRLSQE HQAYRWLGLE 120
  121 EACQLAQFKE MKATLQEGHQ FLCSTPA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.154902
Match:	1xsaA
Description:	Structure of the nudix enzyme AP4A hydrolase from homo sapiens (E63A mutant)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits