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View Structure Prediction Details

Protein: COPD_ARATH
Organism: Arabidopsis thaliana
Length: 527 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COPD_ARATH.

Description E-value Query
Range
Subject
Range
COPD_PONPY - Coatomer subunit delta - Pongo pygmaeus (Orangutan)
COPD_PONAB - Coatomer subunit delta OS=Pongo abelii GN=ARCN1 PE=2 SV=1
382.0 [0..1] [527..1]

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Predicted Domain #1
Region A:
Residues: [1-328]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVLAAAIVV KSGKVIVSRH YVDMSRIRIE GLLAAFPKLV GMGKQHTYIE TENVRYVYQP  60
   61 IEALFLLLVT TKQSNILEDL ATLTLLSKLV PEYSMSLDEE GISRASFELI FAFDEVISLG 120
  121 HKESVTVAQV KQYCEMESHE EKLHKLVMQS KINDTKDVMK RKANEIDKSK IEKNKPGGFS 180
  181 SMGSMGSGRL ESGFNELSIS SGGGGGYGSG SGFGMISDVD PINTKPKDRS RSSVTAPPKS 240
  241 SGMKLGKSGK NQLMESLKAE GEDVIEDVKP TGQSKAAAPP PTDPFTLTVE EKLNVALRRD 300
  301 GGLSSFDMQG TLSLQILNQE DGFVQVQI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.522879
Match: 2bp5M
Description: MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH NON-CANONICAL INTERNALIZATION PEPTIDE VEDYEQGLSG
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [329-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATGENPEILF KTHPNINRDM FNNENILGLK RPDQPFPTGQ GGDGVGLLRW RMQRADESMV  60
   61 PLTINCWPSV SGNETYVSLE YEASSMFDLT NVIISVPLPA LREAPSVRQC DGEWRYDPRN 120
  121 SVLEWSILLI DNSNRSGSME FVVPPVDSSV FFPISVQFAA TSTYSGLKVT GMIPLRGGGG 180
  181 ATPRFVQRTQ LIAQNYQVI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 58.30103
Match: 1bxxA
Description: Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 4.44604247436673 bayes_pls_golite062009
transporter activity 1.6020979054057 bayes_pls_golite062009
protein transporter activity 1.50978938003272 bayes_pls_golite062009
binding 1.47935906574431 bayes_pls_golite062009
protein binding 1.10098179099023 bayes_pls_golite062009
substrate-specific transporter activity 0.890040378421594 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle