YRC Public Data Repository - Protein Structure Prediction

Protein:	TTL4_ARATH
Organism:	Arabidopsis thaliana
Length:	682 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TTL4_ARATH.

Description	E-value	Query Range	Subject Range
gi\|11357441, gi\|... - gi\|6735379\|emb\|CAB68200.1\| putative protein [Arabidopsis thaliana], pir\|\|T45682 hypothetical protein...	315.0	[0..1]	[682..1]
gi\|113475191, gi... - gi\|113475191\|ref\|YP_721252.1\| glycosyl transferase family protein [Trichodesmium erythraeum IMS101],...	313.0	[0..23]	[675..1]
gi\|33640682, gi\|... - gi\|33862569\|ref\|NP_894129.1\| TPR repeat-containing protein [Prochlorococcus marinus str. MIT 9313], ...	296.0	[0..64]	[679..465]
gi\|73670079, gi\|... - gi\|73670079\|ref\|YP_306094.1\| TPR repeat-containing protein [Methanosarcina barkeri str. Fusaro], gi\|...	295.0	[0..41]	[677..261]
gi\|118385554 - gi\|118385554\|ref\|XP_001025906.1\| TPR Domain containing protein [Tetrahymena thermophila] gi\|89307673, gi\|... - gi\|89307673\|gb\|EAS05661.1\| TPR Domain containing protein [Tetrahymena thermophila SB210], gi\|1183855...	290.0	[0..84]	[678..354]

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Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHYRRHSLE PSITSKFRDS LSFQRDDDVI NKPDFRELDF GSPLRPRGSS SAAATPAASG  60
   61 SSSSSSGSAS GKPAVTSQFA RRSHSGELSG LSQTSPVKPG SVNRNLKPGH RRSASAGTPL 120
  121 IYSGLGFSP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [130-206]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNNNNNSSRG GGSGATSPNP GVLPTGNICP SGRILKTGMA TRASVRPETL CTGTANYGHG  60
   61 NIIRTGGKVS HATKAAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.39794
Match:	1w3bA
Description:	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [207-682]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EMSDSEEVKK AGNVMYRKGN YAEALALYDR AISLSPENPA YRSNRAAALA ASGRLEEAVK  60
   61 ECLEAVRCDP SYARAHQRLA SLYLRLGEAE NARRHLCVSG QCPDQADLQR LQTLEKHLRL 120
  121 CTEARKIGDW RTVISEIDAA IANGADSSPQ LVACKAEAFL RLHQIKDSDL CISSIPRLDH 180
  181 HHTQPPEKLF GIVCDAYVLC VQAQVDMALG RFENAIVKVE RAMTIDHSNS PEVVSVLNNV 240
  241 KNVAKARTRG NELFSSGRYS EASVAYGDGL KLDAFNSVLY CNRAACWFKL GMWEKSVDDC 300
  301 NQALRIQPSY TKALLRRAAS YGKLGRWEDA VRDYEVLRKE LPGDSEVAES LQRARNALSN 360
  361 KSEEPKYLGF NNEVEEVSTL DKFKTATSLP GISVFHFKSS SNRQSEAISP FVNTLCLRYP 420
  421 LVHFFKVDVE ESLALAKAES IKKIPTFKIY KKGEKVKEMV CPSHQLLEDS VTHFLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.221849
Match:	2gw1A
Description:	No description for 2gw1A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits