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View Structure Prediction Details

Protein: gi|3089349
Organism: Homo sapiens
Length: 729 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|3089349.

Description E-value Query
Range
Subject
Range
gi|73964085 - gi|73964085|ref|XP_868624.1| PREDICTED: similar to MAP/microtubule affinity-regulating kinase 3 isof...
654.0 [0..1] [729..1]
gi|61354596 - gi|61354596|gb|AAX41026.1| MAP/microtubule affinity-regulating kinase 3 [synthetic construct]
653.0 [0..1] [729..1]
gi|46852166 - gi|46852166|ref|NP_002367.4| MAP/microtubule affinity-regulating kinase 3 isoform c [Homo sapiens]
653.0 [0..1] [729..1]
gi|114654983 - gi|114654983|ref|XP_001138504.1| PREDICTED: MAP/microtubule affinity-regulating kinase 3 isoform 14 ...
652.0 [0..1] [729..1]
gi|251823812, gi... - gi|74141703|dbj|BAE38602.1| unnamed protein product [Mus musculus], gi|251823812|ref|NP_073712.2| MA...
646.0 [0..1] [729..1]

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Predicted Domain #1
Region A:
Residues: [1-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTRTPLPTV NERDTENHTS HGDGRQEVTS RTSRSGARCR NSIASCADEQ PHIGNYRLLK  60
   61 TIGKGNFAKV KLARHILTGR EVAIKIIDKT QLNPTSLQKL FREVRIMKIL NHPNIVKLFE 120
  121 VIETEKTLYL IMEYASGGEV FDYLVAHGRM KEKEARSKFR QIVSAVQYCH QKRIVHRDLK 180
  181 AENLLLDADM NIKIADFGFS NEFTVGGKLD TFCGSPPYAA PELFQGKKYD GPEVDVWSLG 240
  241 VILYTLVSGS LPFDGQNLKE LRERVLRGKY RIPFYMSTDC ENLLKRFLVL NPIKRGTLEQ 300
  301 IMKDRWINAG HEEDELKPFV EPELDISDQK RIDIMVGMGY SQEEIQESLS KMKYDEITAT 360
  361 YLLLGRKSSE LDASDSSSSS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 94.69897
Match: 2qnjA
Description: No description for 2qnjA was found.

Predicted Domain #2
Region A:
Residues: [381-560]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLSLAKVRPS SDLNNSTGQS PHHKVQRSVS SSQKQRRYSD HAGPAIPSVV AYPKRSQTST  60
   61 ADGDLKEDGI SSRKSSGSAV GGKGIAPASP MLGNASNPNK ADIPERKKSS TVPSSNTASG 120
  121 GMTRRNTYVC SERTTADRHS VIQNGKENST IPDQRTPVAS THSISSAATP DRIRFPRGTA 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.967
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #3
Region A:
Residues: [561-621]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRSTFHGQPR ERRTATYNGP PASPSLSHEA TPLSQTRSRG STNLFSKLTS KLTRSRNVSA  60
   61 E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [622-729]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKDENKEAKP RSLRFTWSMK TTSSMDPGDM MREIRKVLDA NNCDYEQRER FLLFCVHGDG  60
   61 HAENLVQWEM EVCKLPRLSL NGVRFKRISG TSIAFKNIAS KIANELKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.0
Match: 1ul7A
Description: Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle