YRC Public Data Repository - Protein Structure Prediction

Protein:	OYE1_SACPS
Organism:	Saccharomyces pastorianus
Length:	400 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OYE1_SACPS.

Description	E-value	Query Range	Subject Range
gi\|50289865, gi\|... - gi\|50289865\|ref\|XP_447364.1\| hypothetical protein CAGL0I02574g [Candida glabrata CBS138], gi\|4952667... gi\|49526674 - gi\|49526674\|emb\|CAG60301.1\| unnamed protein product [Candida glabrata]	390.0	[0..1]	[400..1]
gi\|114704859, gi... - gi\|114704859\|ref\|ZP_01437767.1\| NADH:flavin oxidoreductase/NADH oxidase [Fulvimarina pelagi HTCC2506...	388.0	[0..12]	[394..1]
OYE2_YEAST - NADPH dehydrogenase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OYE2 PE=1 SV=3 OYE2 - Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p wi...	384.0	[0..1]	[399..1]
gi\|23126675, gi\|... - gi\|23126675\|ref\|ZP_00108564.1\| COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family [Nosto...	382.0	[0..11]	[394..1]
gi\|77959187 - gi\|77959187\|ref\|ZP_00823209.1\| COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family [Yersi...	380.0	[0..12]	[389..1]
gi\|89352811, gi\|... - gi\|89358634\|ref\|ZP_01196456.1\| morphinone reductase [Xanthobacter autotrophicus Py2], gi\|89352811\|gb...	379.0	[0..12]	[394..1]

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Predicted Domain #1

Region A:
Residues: [1-400]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFVKDFKPQ ALGDTNLFKP IKIGNNELLH RAVIPPLTRM RALHPGNIPN RDWAVEYYTQ  60
   61 RAQRPGTMII TEGAFISPQA GGYDNAPGVW SEEQMVEWTK IFNAIHEKKS FVWVQLWVLG 120
  121 WAAFPDNLAR DGLRYDSASD NVFMDAEQEA KAKKANNPQH SLTKDEIKQY IKEYVQAAKN 180
  181 SIAAGADGVE IHSANGYLLN QFLDPHSNTR TDEYGGSIEN RARFTLEVVD ALVEAIGHEK 240
  241 VGLRLSPYGV FNSMSGGAET GIVAQYAYVA GELEKRAKAG KRLAFVHLVE PRVTNPFLTE 300
  301 GEGEYEGGSN DFVYSIWKGP VIRAGNFALH PEVVREEVKD KRTLIGYGRF FISNPDLVDR 360
  361 LEKGLPLNKY DRDTFYQMSA HGYIDYPTYE EALKLGWDKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	106.0
Match:	1oyaA
Description:	OLD YELLOW ENZYME AT 2 ANGSTROMS RESOLUTION: OVERALL STRUCTURE, LIGAND BINDING AND COMPARISON WITH RELATED FLAVOPROTEINS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	3.50791144647902	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	2.11027907327307	bayes_pls_golite062009
catalytic activity	1.94749091175302	bayes_pls_golite062009
coenzyme binding	0.99234662301893	bayes_pls_golite062009
binding	0.724672865863266	bayes_pls_golite062009
nucleic acid binding	0.350068675013616	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.0276497014195508	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: