YRC Public Data Repository - Protein Structure Prediction

Protein:	l(2)03709-PB, l(...
Organism:	Drosophila melanogaster
Length:	299 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for l(2)03709-PB, l(....

Description	E-value	Query Range	Subject Range
PHB2_BOVIN - Prohibitin-2 OS=Bos taurus GN=PHB2 PE=2 SV=1	230.0	[0..1]	[299..1]
PHB2_RAT - Prohibitin-2 OS=Rattus norvegicus GN=Phb2 PE=1 SV=1	230.0	[0..1]	[299..1]
gi\|50757151 - gi\|50757151\|ref\|XP_415401.1\| PREDICTED: similar to Erythrocyte band 7 integral membrane protein (Sto...	229.0	[0..2]	[288..388]
gi\|53734337 - gb\|AAH84026.1\| Unknown (protein for MGC:98216) [Xenopus laevis] gi\|114643120 - gi\|114643120\|ref\|XP_508977.2\| PREDICTED: prohibitin 2 isoform 3 [Pan troglodytes] PHB2_MOUSE - Prohibitin-2 OS=Mus musculus GN=Phb2 PE=1 SV=1 gi\|123981810, gi... - gi\|157928262\|gb\|ABW03427.1\| prohibitin 2 [synthetic construct], gi\|123981810\|gb\|ABM82734.1\| prohibit... gi\|109095407 - gi\|109095407\|ref\|XP_001111957.1\| PREDICTED: similar to Prohibitin-2 (B-cell receptor-associated prot... PHB2 - prohibitin 2	229.0	[0..1]	[299..1]
gi\|6671622, gi\|1... - gi\|6671622\|ref\|NP_031557.1\| B-cell receptor-associated protein 37 [Mus musculus], gi\|541734\|emb\|CAA5...	226.0	[0..1]	[299..1]
gi\|55728600 - gi\|55728600\|emb\|CAH91041.1\| hypothetical protein [Pongo abelii] PHB2_PONAB - Prohibitin-2 OS=Pongo abelii GN=PHB2 PE=2 SV=1	225.0	[0..1]	[299..1]
PHB2_XENTR - Prohibitin-2 OS=Xenopus tropicalis GN=phb2 PE=2 SV=1	225.0	[0..1]	[299..1]
gi\|148228072, gi... - gi\|49522786\|gb\|AAH74451.1\| MGC84728 protein [Xenopus laevis], gi\|148228072\|ref\|NP_001086302.1\| MGC84...	222.0	[0..1]	[299..1]
gi\|108871326, gi... - gi\|157131971\|ref\|XP_001662386.1\| prohibitin [Aedes aegypti], gi\|108871326\|gb\|EAT35551.1\| prohibitin ...	221.0	[0..1]	[299..1]

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Predicted Domain #1

Region A:
Residues: [1-75]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQSKLNDLA GKLGKGGPPG LGIGLKVLAA VGAAAYGVSQ SLYTVEGGHR AIIFSRLGGI  60
   61 QSDIYSEGLH VRIPW

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [76-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQYPIIYDIR SRPRKISSPT GSKDLQMINI SLRVLSRPDS LNLPYLHKQL GVDYDEKVLP  60
   61 SICNEVLKSV IAKFNASQLI TQRQQVSLLI RKELVERARD FNIILDDVSL TELSF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.69897
Match:	1winA
Description:	Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.10215477176861	bayes_pls_golite062009
protein binding	0.769979871341236	bayes_pls_golite062009
structural molecule activity	0.591437172549816	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [191-299]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKEYTAAIEA KQVAQQEAQR AVFFVERAKQ EKQQKIVQAE GEAEAAKMLG LAVKQNPAYL  60
   61 KLRKLRAAQS IARTIASSQN KVYLSADSLM LNIQDSGFDD MTEKVYKSK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: