YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|52696234, gi\|...
Organism:	Thermotoga maritima MSB8
Length:	217 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|52696234, gi|....

Description	E-value	Query Range	Subject Range
gi\|60593842, gi\|... - pir\|\|F72422 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) - Thermotoga maritima (strain ... gi\|15642841, gi\|... - gi\|4980553\|gb\|AAD35160.1\|AE001693_6 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutar...	167.0	[0..13]	[217..1]
gi\|56380333, gi\|... - gi\|56420491\|ref\|YP_147809.1\| 2-dehydro-3-deoxyphosphogluconate aldolase [Geobacillus kaustophilus HT...	165.0	[0..13]	[215..4]
gi\|55379686, gi\|... - gi\|55379686\|ref\|YP_137536.1\| 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate ald...	161.0	[0..17]	[217..190]
gi\|23130348 - gi\|23130348\|ref\|ZP_00112165.1\| COG0352: Thiamine monophosphate synthase [Nostoc punctiforme PCC 7310...	157.0	[0..14]	[216..161]
gi\|92114857, gi\|... - gi\|92114857\|ref\|YP_574785.1\| 2-keto-3-deoxy-phosphogluconate aldolase [Chromohalobacter salexigens D...	156.0	[0..1]	[212..1]
gi\|108563462, gi... - gi\|108563462\|ref\|YP_627778.1\| 2-keto-3-deoxy-6-phosphogluconate aldolase [Helicobacter pylori HPAG1]...	156.0	[0..14]	[211..4]
gi\|109714266, gi... - gi\|109947045\|ref\|YP_664273.1\| 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate ...	156.0	[0..14]	[213..8]
gi\|7436631 - pir\|\|C64657 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) - Helicobacter pylori (strain ... gi\|2314248, gi\|1... - gi\|2314248\|gb\|AAD08142.1\| 2-keto-3-deoxy-6-phosphogluconate aldolase (eda) [Helicobacter pylori 2669...	155.0	[0..14]	[211..4]
gi\|23099669, gi\|... - gi\|23099669\|ref\|NP_693135.1\| 2-dehydro-3-deoxyphosphogluconate aldolase [Oceanobacillus iheyensis HT...	155.0	[0..13]	[213..1]
gi\|113461739, gi... - gi\|23467619\|ref\|ZP_00123199.1\| COG0800: 2-keto-3-deoxy-6-phosphogluconate aldolase [Haemophilus somn...	154.0	[0..14]	[213..7]

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Predicted Domain #1

Region A:
Residues: [1-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSDKIHHHH HHMKMEELFK KHKIVAVLRA NSVEEAKEKA LAVFEGGVHL IEITFTVPDA  60
   61 DTVIKELSFL KEKGAIIGAG TVTSVEQCRK AVESGAEFIV SPHLDEEISQ FCKEKGVFYM 120
  121 PGVMTPTELV KAMKLGHTIL KLFPGEVVGP QFVKAMKGPF PNVKFVPTGG VNLDNVCEWF 180
  181 KAGVLAVGVG SALVKGTPDE VREKAKAFVE KIRGCTE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.09691
Match:	1vlwA
Description:	Crystal structure of 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (TM0066) from Thermotoga maritima at 2.30 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.14025337715947	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: