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View Structure Prediction Details

Protein: gi|49259594, gi|...
Organism: Homo sapiens
Length: 238 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49259594, gi|....

Description E-value Query
Range
Subject
Range
gi|51246268, gi|... - gi|51246268|ref|YP_066152.1| exodeoxyribonuclease (ExoA) [Desulfotalea psychrophila LSv54], gi|50877...
196.0 [0..4] [238..224]
gi|106322 - gi|106322|pir||B34087 hypothetical protein (L1H 3' region) - human
194.0 [0..1] [238..6]
gi|60493498, gi|... - gi|60682064|ref|YP_212208.1| exodeoxyribonuclease [Bacteroides fragilis NCTC 9343], gi|60493498|emb|...
gi|52216716, gi|... - gi|53713851|ref|YP_099843.1| exodeoxyribonuclease [Bacteroides fragilis YCH46], gi|52216716|dbj|BAD4...
gi|251946092, gi... - gi|253565813|ref|ZP_04843268.1| exodeoxyribonuclease [Bacteroides sp. 3_2_5], gi|251946092|gb|EES864...
194.0 [0..8] [237..1]

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Predicted Domain #1
Region A:
Residues: [1-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGSNSHITI LTLNINGLNS AIKRHRLASW IKSQDPSVCC IQETHLTCRD THRLKIKGWR  60
   61 KIYQANGKQK KAGVAILVSD KTDFKPTKIK RDKEGHYIMV KGSIQQEELT ILNIYAPNTG 120
  121 APRFIKQVLS DLQRDLDSHT LIMGDFNTPL STLDRSTRQK VNKDTQELNS ALHQADLIDI 180
  181 YRTLHPKSTE YTFFSAPHHT YSKIDHIVGS KALLSKCKRT EIITNYLSDH SAIKLELR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.0
Match: 1vybA
Description: Endonuclease domain of human LINE1 ORF2p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 2.13555370693179 bayes_pls_golite062009
deoxyribonuclease activity 2.05523724828257 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.05365635018354 bayes_pls_golite062009
hydrolase activity 1.91655065797595 bayes_pls_golite062009
exodeoxyribonuclease III activity 1.85973954222311 bayes_pls_golite062009
exodeoxyribonuclease activity 1.51772448052387 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 1.51551179681369 bayes_pls_golite062009
exonuclease activity 1.21933709871113 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.16071290518269 bayes_pls_golite062009
nuclease activity 0.48571734782839 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle