YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|49258638
Organism:	Escherichia coli
Length:	297 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49258638.

Description	E-value	Query Range	Subject Range
gi\|49425219 - gi\|49425219\|gb\|AAT66004.1\| Shiga toxin 2 subunit A [Bacteriophage VTB323] gi\|49425216 - gi\|49425216\|gb\|AAT66002.1\| Shiga toxin 2 subunit A [Bacteriophage O157-379] gi\|49425213 - gi\|49425213\|gb\|AAT66000.1\| Shiga toxin 2 subunit A [Bacteriophage O157-310]	329.0	[0..1]	[297..23]
gi\|49425180 - gi\|49425180\|gb\|AAT65978.1\| Shiga toxin 2 subunit A [Bacteriophage O157-572] gi\|49425177 - gi\|49425177\|gb\|AAT65976.1\| Shiga toxin 2 subunit A [Bacteriophage A557] gi\|49425174 - gi\|49425174\|gb\|AAT65974.1\| Shiga toxin 2 subunit A [Bacteriophage A534] gi\|49425171 - gi\|49425171\|gb\|AAT65972.1\| Shiga toxin 2 subunit A [Bacteriophage A75]	329.0	[0..1]	[297..23]
gi\|168755149, gi... - gi\|189357665\|gb\|EDU76084.1\| shiga toxin A-chain [Escherichia coli O157:H7 str. EC4401], gi\|168755149... gi\|209447166, gi... - gi\|209447166\|ref\|YP_002274251.1\| verocytotoxin 2 variant 2c subunit A [Stx2-converting phage 1717], ... gi\|209397665, gi... - gi\|209397665\|ref\|YP_002271221.1\| shiga toxin subunit A [Escherichia coli O157:H7 str. EC4115], gi\|20... gi\|55859417, gi\|... - gi\|55859417\|emb\|CAE53948.1\| shiga toxin 2A-subunit [Bacteriophage 2851], gi\|209407409\|emb\|CAQ82025.1... gi\|88759238, gi\|... - gi\|88759238\|dbj\|BAE79924.1\| Shiga toxin 2 A subunit [Escherichia coli O157:H7], gi\|88759230\|dbj\|BAE7... gi\|41581519, gi\|... - gi\|41581519\|gb\|AAS07596.1\| verocytotoxin 2 variant A subunit [Escherichia coli], gi\|3869150\|dbj\|BAA3... gi\|49425225 - gi\|49425225\|gb\|AAT66008.1\| Shiga toxin 2 subunit A [Bacteriophage VTB60] gi\|49425222 - gi\|49425222\|gb\|AAT66006.1\| Shiga toxin 2 subunit A [Bacteriophage VTB46] gi\|49425210 - gi\|49425210\|gb\|AAT65998.1\| Shiga toxin 2 subunit A [Bacteriophage O157-330] gi\|49425207 - gi\|49425207\|gb\|AAT65996.1\| Shiga toxin 2 subunit A [Bacteriophage O157-292] gi\|254593159, gi... - gi\|254793759\|ref\|YP_003078596.1\| Shiga-like toxin II subunit A precursor [Escherichia coli O157:H7 s... gi\|49425204 - gi\|49425204\|gb\|AAT65994.1\| Shiga toxin 2 subunit A [Bacteriophage A580] gi\|49425201 - gi\|49425201\|gb\|AAT65992.1\| Shiga toxin 2 subunit A [Bacteriophage A549] gi\|49425198 - gi\|49425198\|gb\|AAT65990.1\| Shiga toxin 2 subunit A [Bacteriophage A315] gi\|49425195 - gi\|49425195\|gb\|AAT65988.1\| Shiga toxin 2 subunit A [Bacteriophage A312] gi\|23343474 - gi\|23343474\|emb\|CAC95105.1\| shiga toxin 2, subunit A [Bacteriophage Nil2]	329.0	[0..1]	[297..23]
gi\|49425231 - gi\|49425231\|gb\|AAT66012.1\| Shiga toxin 2 subunit A [Bacteriophage O157-469]	329.0	[0..1]	[297..23]
gi\|209157541, gi... - gi\|209396141\|ref\|YP_002271797.1\| shiga toxin subunit A [Escherichia coli O157:H7 str. EC4115], gi\|20... gi\|19911733, gi\|... - gi\|20065941\|ref\|NP_613024.1\| Shiga toxin2 subunit A [Stx2 converting phage I], gi\|19911733\|dbj\|BAB87... gi\|208805898, gi... - gi\|208805898\|ref\|ZP_03248235.1\| shiga toxin subunit A [Escherichia coli O157:H7 str. EC4206], gi\|208... gi\|195935769 - gi\|195935769\|ref\|ZP_03081151.1\| Shiga toxin 2 subunit A [Escherichia coli O157:H7 str. EC4024] gi\|14325229, gi\|... - gi\|80971645\|gb\|ABB52794.1\| Shiga toxin 2 subunit A [Escherichia coli], gi\|80971642\|gb\|ABB52792.1\| Sh... gi\|108743120 - gi\|108743120\|emb\|CAJ76694.1\| shiga toxin II subunit A precursor [Escherichia coli O111:NM] gi\|32128324, gi\|... - gi\|32171146\|ref\|NP_859390.1\| Shiga toxin2 subunit A [Stx2 converting phage II], gi\|32128324\|dbj\|BAC7... gi\|15830459, gi\|... - gi\|15830459\|ref\|NP_309232.1\| Shiga toxin 2 subunit A [Escherichia coli O157:H7 str. Sakai], gi\|13360... gi\|5881632, gi\|9... - gi\|9633436\|ref\|NP_050539.1\| Shiga toxin 2 subunit A [Enterobacteria phage VT2-Sakai], gi\|5881632\|dbj... gi\|23320677, gi\|... - gi\|23320677\|gb\|AAN12304.1\| Shiga toxin 2 subunit A [Escherichia coli O157:H-], gi\|23320674\|gb\|AAN123... gi\|27545500 - gi\|27545500\|gb\|AAN59920.2\| shiga toxin 2 subunit A [Bacteriophage LC159] gi\|115500803, gi... - gi\|116221993\|ref\|YP_794048.1\| shiga toxin 2 subunit A [Stx2-converting phage 86], gi\|115500803\|dbj\|B... gi\|188017333, gi... - gi\|188017333\|gb\|EDU55455.1\| shiga toxin subunit A [Escherichia coli O157:H7 str. EC4113], gi\|1687482... gi\|15830459, gi\|... - gi\|7649862\|dbj\|BAA94140.1\| shiga toxin 2 subunit A [Enterobacteria phage VT2-Sakai], gi\|15830459\|ref... gi\|254593671, gi... - gi\|254794271\|ref\|YP_003079108.1\| shiga toxin II subunit A [Escherichia coli O157:H7 str. TW14359], g... gi\|12514316, gi\|... - gi\|15800960\|ref\|NP_286976.1\| shiga-like toxin II A subunit encoded by bacteriophage BP-933W [Escheri... gi\|24415901 - gi\|24415901\|gb\|AAN59925.1\| shiga toxin 2 A subunit [Bacteriophage SC370] gi\|170783650, gi... - gi\|170783650\|ref\|YP_001648932.1\| Shiga toxin 2 subunit A [Enterobacteria phage Min27], gi\|163955744\|... STXA_BP933 - Shiga-like toxin 2 subunit A OS=Enterobacteria phage 933W GN=stxA2 PE=1 SV=2 gi\|189378992, gi... - gi\|189378992\|gb\|EDU97408.1\| shiga toxin A-chain [Escherichia coli O157:H7 str. EC508], gi\|168798568\|... gi\|168772875, gi... - gi\|187771305\|gb\|EDU35149.1\| shiga toxin subunit A [Escherichia coli O157:H7 str. EC4196], gi\|1687728... gi\|189363010, gi... - gi\|189363010\|gb\|EDU81429.1\| shiga toxin subunit A [Escherichia coli O157:H7 str. EC4486], gi\|1687680...	328.0	[0..1]	[297..23]
gi\|49425228 - gi\|49425228\|gb\|AAT66010.1\| Shiga toxin 2 subunit A [Bacteriophage A397]	327.0	[0..1]	[297..23]
gi\|80971636, gi\|... - gi\|8439281\|emb\|CAB94148.1\| shiga toxin 2 A subunit [Escherichia coli], gi\|80971639\|gb\|ABB52790.1\| Sh... gi\|22087610, gi\|... - gi\|22087618\|gb\|AAM90986.1\|AF525041_1 Shiga toxin 2 subunit A [Escherichia coli O157:H-], gi\|22087614...	327.0	[0..1]	[297..23]

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Predicted Domain #1

Region A:
Residues: [1-297]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REFTIDFSTQ QSYVSSLNSI RTEISTPLEH ISQGTTSVSV INHTPPGSYF AVDIRGLDVY  60
   61 QARFDHLRLI IEQNNLYVAG FVNTATNTFY RFSDFTHISV PGVTTVSMTT DSSYTTLQRV 120
  121 AALERSGMQI SRHSLVSSYL ALMEFSGNTM TRDASRAVLR FVTVTAEALR FRQIQREFRQ 180
  181 ALSETAPVYT MTPGDVDLTL NWGRISNVLP EYRGEDGVRV GRISFNNISA ILGTVAVILN 240
  241 CHHQGARSVR AVNEESQPEC QITGDRPVIK INNTLWESNT AAAFLNRKSQ FLYTTGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	88.69897
Match:	1r4pA
Description:	Shiga toxin type 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.372436499192166	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: