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View Structure Prediction Details

Protein: gi|168267488
Organism: synthetic construct
Length: 1042 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168267488.

Description E-value Query
Range
Subject
Range
gi|20521123 - gi|20521123|dbj|BAA31634.2| KIAA0659 protein [Homo sapiens]
0.0 [1..1042] [8..1049]
DGLA_MOUSE - Sn1-specific diacylglycerol lipase alpha OS=Mus musculus GN=Dagla PE=1 SV=1
0.0 [1..1042] [1..1044]
DGLA_RAT - Sn1-specific diacylglycerol lipase alpha OS=Rattus norvegicus GN=Dagla PE=1 SV=1
0.0 [1..1042] [1..1044]
gi|114637909 - gi|114637909|ref|XP_508479.2| PREDICTED: neural stem cell-derived dendrite regulator [Pan troglodyte...
0.0 [1..1042] [36..1072]
gi|76657571 - gi|76657571|ref|XP_601967.2| PREDICTED: similar to neural stem cell-derived dendrite regulator isofo...
0.0 [1..1042] [1..1040]
gi|109105916 - gi|109105916|ref|XP_001118508.1| PREDICTED: similar to neural stem cell-derived dendrite regulator [...
0.0 [1..1042] [1..1089]
gi|47230479 - gi|47230479|emb|CAF99672.1| unnamed protein product [Tetraodon nigroviridis]
0.0 [1..1005] [1..991]
gi|68362886 - gi|68362886|ref|XP_697873.1| PREDICTED: similar to neural stem cell-derived dendrite regulator [Dani...
0.0 [33..1005] [1302..2289]
gi|50794489 - gi|50794489|ref|XP_423696.1| PREDICTED: similar to chromosome 11 open reading frame 11; neural stem ...
0.0 [1..736] [1..732]
inaE-PD - The gene inactivation no afterpotential E is referred to in FlyBase by the symbol Dmel\inaE (CG33174...
0.0 [1..674] [1..701]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGIVVFRRR WSVGSDDLVL PAIFLFLLHT TWFVILSVVL FGLVYNPHEA CSLNLVDHGR  60
   61 GYLGILLSCM IAEMAIIWLS MRGGILYTEP RDSMQYVLYV RLAILVIEFI YAIVGIVWLT 120
  121 QYYTSCNDLT AKNVT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [136-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGMVVCNWVV ILSVCITVLC VFDPTGRTFV KLRATKRRQR NLRTYNLRHR LEEGQATSWS  60
   61 RRLKVFLCCT RTKDSQSDAY SEIAYLFAEF FRDLDIVPSD IIAGLVLLRQ RQRAKRNAVL 120
  121 DEANNDILAF LSGMPVTRNT KYLDLKNSQE MLRYKEVCYY MLFALAAYGW PMYLMRKPAC 180
  181 GLCQLAR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [323-585]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SCSCCLCPAR PRFAPGVTIE EDNCCGCNAI AIRRHFLDEN MTAVDIVYTS CHDAVYETPF  60
   61 YVAVDHDKKK VVISIRGTLS PKDALTDLTG DAERLPVEGH HGTWLGHKGM VLSAEYIKKK 120
  121 LEQEMVLSQA FGRDLGRGTK HYGLIVVGHS LGAGTAAILS FLLRPQYPTL KCFAYSPPGG 180
  181 LLSEDAMEYS KEFVTAVVLG KDLVPRIGLS QLEGFRRQLL DVLQRSTKPK WRIIVGATKC 240
  241 IPKSELPEEV EVTTLASTRL WTH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.69897
Match: 4tglA
Description: CATALYSIS AT THE INTERFACE: THE ANATOMY OF A CONFORMATIONAL CHANGE IN A TRIGLYCERIDE LIPASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.866238607554457 bayes_pls_golite062009
hydrolase activity 0.52702612560045 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [586-677]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSDLTIALSA STPLYPPGRI IHVVHNHPAE QCCCCEQEEP TYFAIWGDNK AFNEVIISPA  60
   61 MLHEHLPYVV MEGLNKVLEN YNKGKTALLS AA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [678-750]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVMVSPTEVD LTPELIFQQQ PLPTGPPMPT GLALELPTAD HRNSSVRSKS QSEMSLEGFS  60
   61 EGRLLSPVVA AAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [751-889]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQDPVELLLL STQERLAAEL QARRAPLATM ESLSDTESLY SFDSRRSSGF RSIRGSPSLH  60
   61 AVLERDEGHL FYIDPAIPEE NPSLSSRTEL LAADSLSKHS QDTQPLEAAL GSGGVTPERP 120
  121 PSAAANDEEE EVGGGGGGP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [890-1042]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASRGELALHN GRLGDSPSPQ VLEFAEFIDS LFNLDSKSSS FQDLYCMVVP ESPTSDYAEG  60
   61 PKSPSQQEIL LRAQFEPNLV PKPPRLFAGS ADPSSGISLS PSFPLSSSGE LMDLTPTGLS 120
  121 SQECLAADKI RTSTPTGHGA SPAKQDELVI SAR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle