YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|50513371
Organism:	Escherichia coli
Length:	160 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|50513371.

Description	E-value	Query Range	Subject Range
gi\|86609102 - gi\|86609102\|ref\|YP_477864.1\| sensory box histidine kinase/response regulator [Cyanobacteria bacteriu... gi\|86557644, gi\|... - gi\|86609102\|ref\|YP_477864.1\| sensory box histidine kinase/response regulator [Synechococcus sp. JA-2...	167.0	[0..1]	[160..882]
gi\|71676531, gi\|... - gi\|71676531\|ref\|ZP_00674272.1\| Guanylate cyclase:Response regulator receiver:ATP-binding region, ATP...	166.0	[0..1]	[158..515]
gi\|86554855, gi\|... - gi\|86606313\|ref\|YP_475076.1\| sensory box histidine kinase/response regulator [Synechococcus sp. JA-3... gi\|86606313 - gi\|86606313\|ref\|YP_475076.1\| sensory box histidine kinase/response regulator [Cyanobacteria bacteriu...	166.0	[0..1]	[159..890]
gi\|148654385, gi... - gi\|148654385\|ref\|YP_001274590.1\| integral membrane sensor hybrid histidine kinase [Roseiflexus sp. R...	164.0	[0..1]	[158..264]
gi\|71839290, gi\|... - gi\|71839290\|ref\|ZP_00679041.1\| PAS [Pelobacter propionicus DSM 2379], gi\|71740223\|gb\|EAO35390.1\| PAS...	163.0	[0..1]	[160..701]
gi\|84622139, gi\|... - gi\|84622139\|ref\|YP_449511.1\| two-component system sensor protein [Xanthomonas oryzae pv. oryzae MAFF... gi\|58424736, gi\|... - gi\|58580142\|ref\|YP_199158.1\| two-component system sensor protein [Xanthomonas oryzae pv. oryzae KACC...	162.0	[0..1]	[158..177]
gi\|78046084, gi\|... - gi\|78046084\|ref\|YP_362259.1\| two-component system sensor protein [Xanthomonas campestris pv. vesicat...	162.0	[0..1]	[158..177]
gi\|21241265, gi\|... - gi\|21241265\|ref\|NP_640847.1\| two-component system sensor protein [Xanthomonas axonopodis pv. citri s...	161.0	[0..1]	[158..177]
gi\|32401164 - gi\|32401164\|gb\|AAP80772.1\|AF525283_4 MmoS [Methylococcus capsulatus]	161.0	[0..1]	[159..587]
gi\|53758420, gi\|... - gi\|53804659\|ref\|YP_113669.1\| sensory box histidine kinase/response regulator [Methylococcus capsulat...	161.0	[0..1]	[159..587]

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Predicted Domain #1

Region A:
Residues: [1-160]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPGTRVTESI HKVAERVVTL VSMELPDNVR LIRDYDPSLP ELAHDPDQIE QVLLNIVRNA  60
   61 LQALGPEGGE IILRTRTAFQ LTLHGERYRL AARIDVEDNG PGIPPHLQDT LFYPMVSGRE 120
  121 GGTGLGLSIA RNLIDQHSGK IEFTSWPGHT EFSVYLPIRK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.0
Match:	1r62A
Description:	Crystal structure of the C-terminal Domain of the Two-Component System Transmitter Protein NRII (NtrB)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.57884608485164	bayes_pls_golite062009
transferase activity	0.66560190725226	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.65281383212182	bayes_pls_golite062009
kinase activity	0.64987928624127	bayes_pls_golite062009
signal transducer activity	0.47895126364598	bayes_pls_golite062009
molecular transducer activity	0.47895126364598	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.41458536707017	bayes_pls_golite062009
protein kinase activity	0.41262128363539	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	0.270144402236579	bayes_pls_golite062009
protein histidine kinase activity	0.27006997723077	bayes_pls_golite062009
two-component sensor activity	0.22080838371957	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: