YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|119619970, gi...
Organism: Homo sapiens
Length: 584 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119619970, gi....

Description E-value Query
Range
Subject
Range
gi|71296672 - gi|71296672|gb|AAH40458.1| CTNNA2 protein [Homo sapiens]
0.0 [11..584] [114..687]
gi|55733167 - gi|55733167|emb|CAH93267.1| hypothetical protein [Pongo abelii]
gi|55733167|emb|... - hypothetical protein [Pongo pygmaeus]
0.0 [11..584] [48..621]
gi|109103591 - gi|109103591|ref|XP_001112889.1| PREDICTED: catenin (cadherin-associated protein), alpha 2 isoform 1...
0.0 [11..584] [366..963]
gi|74182805 - gi|74182805|dbj|BAE34726.1| unnamed protein product [Mus musculus]
0.0 [11..584] [345..918]
CTNA1_RABIT - Catenin alpha-1 OS=Oryctolagus cuniculus GN=CTNNA1 PE=3 SV=1
0.0 [11..583] [335..906]
gi|114601995 - gi|114601995|ref|XP_001171892.1| PREDICTED: catenin, alpha 1 isoform 13 [Pan troglodytes]
0.0 [11..583] [262..833]
CTNA1_BOVIN - Catenin alpha-1 OS=Bos taurus GN=CTNNA1 PE=2 SV=1
0.0 [11..583] [334..905]

Back

Predicted Domain #1
Region A:
Residues: [1-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGWRRPLQS VGKVCEKNMK TSEMHTMSGA QTGRKEKGDP LNIAIDKMTK KTRDLRRQLR  60
   61 KAVMDHISDS FLETNVPLLV LIEAAKSGNE KEVKEYAQVF REHANKLVEV ANLACSISNN 120
  121 EEGVKLVRMA ATQIDSLCPQ VINAALTLAA RPQSKVAQDN MDVFKDQWEK QVRVLTEAVD 180
  181 DITSVDDFLS VSENHILEDV NKCVIALQEG DVDTLDRTAG AIRGRAARVI HIINAEMENY 240
  241 EAGVYTEKVL EATKLLSETV MPRFAEQVEV AIEALSANVP QPFEENEFID ASRLVYDGVR 300
  301 DIRKAVLMIR TPEELEDDSD FEQEDYDVRS RTSV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 108.0
Match: 1l7cA
Description: alpha-catenin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [335-584]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTEDDQLIAG QSARAIMAQL PQEEKAKIAE QVEIFHQEKS KLDAEVAKWD DSGNDIIVLA  60
   61 KQMCMIMMEM TDFTRGKGPL KNTSDVINAA KKIAEAGSRM DKLARAVADQ CPDSACKQDL 120
  121 LAYLQRIALY CHQLNICSKV KAEVQNLGGE LIVSGLDSAT SLIQAAKNLM NAVVLTVKAS 180
  181 YVASTKYQKV YGTAAVNSPV VSWKMKAPEK KPLVKREKPE EFQTRVRRGS QKKHISPVQA 240
  241 LSEFKAMDSF 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.69897
Match: 1rkeB
Description: Human vinculin head (1-258) in complex with human vinculin tail (879-1066)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.425289494704085 bayes_pls_golite062009
protein binding 0.19527989782766 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle