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View Structure Prediction Details

Protein: gi|220957180, gi...
Organism: synthetic construct
Length: 527 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220957180, gi....

Description E-value Query
Range
Subject
Range
gi|54695952 - gi|54695952|gb|AAV38348.1| Wiskott-Aldrich syndrome-like [synthetic construct]
270.0 [0..1] [309..1]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGMRSQDG PRAKVNAAST LLTQEENEAV FKLLGKKCQT LNTAVVQIYK TEGSAHAHWK  60
   61 KRHTGVVCFV KDSAIRSYFM RAYCLIKNEL IWEHEIYDGM EVVKSRPFLL TFEGSDGHVG 120
  121 LNFVSEEECD SFFRIVDAT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.522879
Match: 1mkeA
Description: Actin regulatory protein WASP
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [140-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IETRNRKRQE KRNRQKSQQA PNAPLPQVQR EPARPPPMQG GLSSTDGVQL RNNKINSVTL  60
   61 TPAPAPAQSK NFLSSSFGLG NNAKDKKRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [229-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTKADISRPT NFVHLSHVGW DAQKGFDLAG NENDEVLNEF FVKAGVSEVE LKDRDTRAFI  60
   61 YDFIQSNNVL ASVKQYSVES PTETAAPMPP PVPTRHPSNG NQRTAPPLPP A

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.03
Match: 1ej5A
Description: Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [340-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQPPPAVPVT VPGAARAPPP PNRPPPISTA PPPPPVSAPV VAPPPPPPPP PAAVPPPPPP  60
   61 PMPVGEIPVI TTTHAPTQAA RPAAPAAPDP RNALMDAIRK GTQLKKVDTT ALSTGSGDSR 120
  121 SDLMKDIRQG TVLKPAKERE LGSQRNSDSG AGTDALADAL RRALAARGNA IHSDEDETES 180
  181 SDNEGEWD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle