YRC Public Data Repository - Protein Structure Prediction

Protein:	MTNB_DROSI
Organism:	Drosophila simulans
Length:	227 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTNB_DROSI.

Description	E-value	Query Range	Subject Range
MTNB_XENTR - Methylthioribulose-1-phosphate dehydratase OS=Xenopus tropicalis GN=apip PE=2 SV=1	225.0	[0..10]	[224..17]
MTNB_XENLA - Methylthioribulose-1-phosphate dehydratase OS=Xenopus laevis GN=apip PE=2 SV=1	224.0	[0..10]	[224..17]
MTNB_BOVIN - Methylthioribulose-1-phosphate dehydratase OS=Bos taurus GN=APIP PE=2 SV=1	220.0	[0..10]	[224..20]
gi\|26346639, gi\|... - gi\|31981004\|ref\|NP_062709.2\| APAF1 interacting protein [Mus musculus], gi\|26346639\|dbj\|BAC36968.1\| u...	220.0	[0..10]	[226..19]
gi\|114636956 - gi\|114636956\|ref\|XP_508364.2\| PREDICTED: APAF1 interacting protein isoform 4 [Pan troglodytes] APIP - APAF1 interacting protein	219.0	[0..10]	[226..20]
gi\|109470291, gi... - gi\|27702700\|ref\|XP_215785.1\| PREDICTED: similar to APAF1 interacting protein [Rattus norvegicus], gi...	219.0	[0..10]	[226..19]
gi\|14250071 - gi\|14250071\|gb\|AAH08440.1\| APAF1 interacting protein [Homo sapiens]	218.0	[0..10]	[226..20]

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Predicted Domain #1

Region A:
Residues: [1-227]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALSIFKDLP AEHPRHLIPS LCRQFYHLGW VTGTGGGMSI KYNDEIYIAP SGVQKERMQP  60
   61 EDLFVQDITG KDLQLPPEIK GLKKSQCTPL FMLAYQHRQA GAVIHTHSQH AVMATLLWPG 120
  121 KTFRCTHLEM IKGVYDEADK RYLRYDEELV VPIIENTPFE RDLADSMYAA MMEYPGCSAI 180
  181 LVRRHGVYVW GQNWEKAKTM SECYDYLFSI AVEMKKAGID PEKFESS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.69897
Match:	1jdiA
Description:	L-ribulose-5-phosphate 4-epimerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.89539096965643	bayes_pls_golite062009
catalytic activity	1.58067730905989	bayes_pls_golite062009
protein binding	0.401574215469404	bayes_pls_golite062009
lyase activity	0.114082266751758	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: