YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213427506
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E02-1180
Length:	382 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213427506.

Description	E-value	Query Range	Subject Range
CARA_SALTY - Carbamoyl-phosphate synthase small chain OS=Salmonella typhimurium GN=carA PE=3 SV=2 CARA_SALTY - Carbamoyl-phosphate synthase small chain OS=Salmonella typhimurium GN=carA PE=3 SV=2 gi\|167989924, gi... - gi\|205331492\|gb\|EDZ18256.1\| carbamoyl-phosphate synthase, small subunit [Salmonella enterica subsp. ... gi\|197264738, gi... - gi\|197264738\|ref\|ZP_03164812.1\| carbamoyl-phosphate synthase, small subunit [Salmonella enterica sub... lcl\|NC_016856.1_... - [gene=carA] [protein=carbamoyl phosphate synthase small subunit] [protein_id=YP_005235710.1] [locati... CARA_SALTY - Carbamoyl-phosphate synthase small chain OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700...	0.0	[1..382]	[1..382]
gi\|62126263, gi\|... - gi\|62178630\|ref\|YP_215047.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subsp. ...	0.0	[1..382]	[1..382]
gi\|56412338, gi\|... - gi\|56412338\|ref\|YP_149413.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subsp. ... gi\|238911125 - gi\|238911125\|ref\|ZP_04654962.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subs... gi\|197361275, gi... - gi\|197361275\|ref\|YP_002140910.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica sub...	0.0	[1..382]	[1..382]
CARA_ECOL6 - Carbamoyl-phosphate synthase small chain OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UP... gi\|218425471, gi... - gi\|218687907\|ref\|YP_002396119.1\| carbamoyl phosphate synthase small subunit [Escherichia coli ED1a],... gi\|218556970, gi... - gi\|218556970\|ref\|YP_002389883.1\| carbamoyl phosphate synthase small subunit [Escherichia coli S88], ... CARA_ECOL6 - Carbamoyl-phosphate synthase small chain OS=Escherichia coli O6 GN=carA PE=3 SV=2	0.0	[1..382]	[1..382]
gi\|190905613, gi... - gi\|191174119\|ref\|ZP_03035633.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli F11], ... gi\|110341836, gi... - gi\|110640244\|ref\|YP_667972.1\| carbamoyl phosphate synthase small subunit [Escherichia coli 536], gi\|...	0.0	[1..382]	[1..382]
CARA_SALTI - Carbamoyl-phosphate synthase small chain OS=Salmonella typhi GN=carA PE=3 SV=1 CARA_SALTI - Carbamoyl-phosphate synthase small chain OS=Salmonella typhi GN=carA PE=3 SV=1 gi\|16759059 - gi\|16759059\|ref\|NP_454676.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subsp. ...	0.0	[1..382]	[1..382]
gi\|1750391\|gb\|AA... - carbamoylphosphate synthetase small subunit [Salmonella typhimurium], carbamoyl-phosphate synthetase gi\|552013, gi\|79... - pir\|\|S01319 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) small chain - Salmonel...	0.0	[1..382]	[1..382]
gi\|189356065, gi... - gi\|189356065\|gb\|EDU74484.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H7 st... gi\|168762794, gi... - gi\|189366993\|gb\|EDU85409.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H7 st... gi\|168766722, gi... - gi\|189364056\|gb\|EDU82475.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H7 st... gi\|187767725, gi... - gi\|187767725\|gb\|EDU31569.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H7 st... gi\|168751712, gi... - gi\|188014317\|gb\|EDU52439.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H7 st... gi\|81244059, gi\|... - gi\|82542648\|ref\|YP_406595.1\| carbamoyl phosphate synthase small subunit [Shigella boydii Sb227], gi\|... gi\|74310650, gi\|... - gi\|74310650\|ref\|YP_309069.1\| carbamoyl phosphate synthase small subunit [Shigella sonnei Ss046], gi\|... CARA_ECOLI - Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) (Carbamoyl-phosphate synthetase glutamine chai... gi\|21321914, gi\|... - gi\|89106916\|ref\|AP_000696.1\| carbamoyl phosphate synthetase small subunit, glutamine amidotransferas... gi\|15829289, gi\|... - gi\|15829289\|ref\|NP_308062.1\| carbamoyl phosphate synthase small subunit [Escherichia coli O157:H7 st... EG10134 - carbamoyl phosphate synthetase small subunit, glutamine amidotransferase / Carbamoyl phosphate synth... gi\|157158284, gi... - gi\|157158284\|ref\|YP_001461201.1\| carbamoyl phosphate synthase small subunit [Escherichia coli E24377... gi\|195937705 - gi\|195937705\|ref\|ZP_03083087.1\| carbamoyl phosphate synthase small subunit [Escherichia coli O157:H7... CARA_ECO57 - Carbamoyl-phosphate synthase small chain OS=Escherichia coli O157:H7 GN=carA PE=3 SV=1 gi\|208727189, gi... - gi\|208807388\|ref\|ZP_03249725.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H... gi\|208734101, gi... - gi\|208812824\|ref\|ZP_03254153.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H... gi\|15799714, gi\|... - gi\|15799714\|ref\|NP_285726.1\| carbamoyl phosphate synthase small subunit [Escherichia coli O157:H7 ED... gi\|208738457, gi... - gi\|208818334\|ref\|ZP_03258654.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H... gi\|192955714, gi... - gi\|193070984\|ref\|ZP_03051913.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli E11001... gi\|194412082, gi... - gi\|194429863\|ref\|ZP_03062375.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli B171],... gi\|194434557, gi... - gi\|194434557\|ref\|ZP_03066815.1\| carbamoyl-phosphate synthase, small subunit [Shigella dysenteriae 10... gi\|194421371, gi... - gi\|194439686\|ref\|ZP_03071756.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli 101-1]... gi\|187733195, gi... - gi\|187733195\|ref\|YP_001878856.1\| carbamoyl-phosphate synthase, small subunit [Shigella boydii CDC 30... gi\|188487680, gi... - gi\|188492481\|ref\|ZP_02999751.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli 53638]... gi\|191168894, gi... - gi\|191168894\|ref\|ZP_03030665.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli B7A], ... gi\|192926138, gi... - gi\|193066213\|ref\|ZP_03047266.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli E22], ... gi\|168781731, gi... - gi\|189000705\|gb\|EDU69691.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H7 st... gi\|168785085, gi... - gi\|189374859\|gb\|EDU93275.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H7 st... gi\|189376014, gi... - gi\|189376014\|gb\|EDU94430.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H7 st... gi\|157065180, gi... - gi\|157159500\|ref\|YP_001456818.1\| carbamoyl phosphate synthase small subunit [Escherichia coli HS], g... gi\|169887530, gi... - gi\|170079695\|ref\|YP_001729015.1\| carbamoyl phosphate synthetase small subunit, glutamine amidotransf... EG10134 - carbamoyl phosphate synthetase small subunit, glutamine amidotransferase / Carbamoyl phosphate synth... gi\|238899437, gi... - gi\|238899437\|ref\|YP_002925233.1\| carbamoyl phosphate synthetase small subunit, glutamine amidotransf... gi\|209161289, gi... - gi\|209399889\|ref\|YP_002268639.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:... gi\|253972059, gi... - gi\|254160158\|ref\|YP_003043266.1\| carbamoyl-phosphate synthase small subunit [Escherichia coli B str.... gi\|217322759, gi... - gi\|217326538\|ref\|ZP_03442622.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H... gi\|254791168, gi... - gi\|254791168\|ref\|YP_003076005.1\| carbamoyl phosphate synthetase small subunit, glutamine amidotransf... gi\|218552616, gi... - gi\|218552616\|ref\|YP_002385529.1\| carbamoyl phosphate synthase small subunit [Escherichia coli IAI1],... gi\|251783599, gi... - gi\|251783599\|ref\|YP_002997903.1\| hypothetical protein B21_00035 [Escherichia coli BL21], gi\|24237587... gi\|218350235, gi... - gi\|218693503\|ref\|YP_002401170.1\| carbamoyl phosphate synthase small subunit [Escherichia coli 55989]... gi\|253774935, gi... - gi\|254286961\|ref\|YP_003052709.1\| carbamoyl-phosphate synthase small subunit [Escherichia coli BL21(D...	0.0	[1..382]	[1..382]
gi\|26245955, gi\|... - gi\|26245955\|ref\|NP_751994.1\| carbamoyl phosphate synthase small subunit [Escherichia coli CFT073], g... gi\|117622322, gi... - gi\|117622322\|ref\|YP_851235.1\| carbamoyl phosphate synthase small subunit [Escherichia coli APEC O1],... gi\|91209091, gi\|... - gi\|91209091\|ref\|YP_539077.1\| carbamoyl phosphate synthase small subunit [Escherichia coli UTI89], gi... gi\|226902086, gi... - gi\|237704174\|ref\|ZP_04534655.1\| carbamoyl-phosphate synthase subunit small [Escherichia sp. 3_2_53FA... gi\|227885070, gi... - gi\|227885070\|ref\|ZP_04002875.1\| carbamoyl phosphate synthase small subunit [Escherichia coli 83972],...	0.0	[1..382]	[10..391]
gi\|4929942, gi\|4... - gi\|5821983\|pdb\|1CE8\|H Chain H, Carbamoyl Phosphate Synthetase From Escherichis Coli With Complexed W...	0.0	[1..382]	[1..382]

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Predicted Domain #1

Region A:
Residues: [1-382]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKSALLVLE DGTQFHGRAI GATGSAVGEV VFNTSMTGYQ EILTDPSYSR QIVTLTYPHI  60
   61 GNVGTNEADE ESSQVHAQGL VIRDLPLIAS NFRNTEDLSS YLKRHNIVAI ADIDTRKLTR 120
  121 LLREKGAQNG CIIAGDSPDA KLALEKAKAF PGLNGMDLAK EVTTAETYRW TQGSWTLKDG 180
  181 LPEAKSEDDL PFHVVAYDFG AKRNILRMLV DRGCRLTVVP AQTSAEEVLK MNPDGIFLSN 240
  241 GPGDPAPCDY AIEAIKKFLQ TDIPVFGICL GHQLLALASG AKTVKMKFGH HGGNHPVKDM 300
  301 DRNVVMITAQ NHGFAVDEDS LPANLRVTHK SLFDGTLQGI HRTDKPAFSF QGHPEASPGP 360
  361 HDAAPLFDHF IELIKHYRSS AK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	124.0
Match:	1cs0B
Description:	Carbamoyl phosphate synthetase, small subunit N-terminal domain; Carbamoyl phosphate synthetase, small subunit C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	9.74519370915839	bayes_pls_golite062009
carbamoyl-phosphate synthase activity	9.70414577567935	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	9.14496558670743	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	7.05319676113266	bayes_pls_golite062009
4-amino-4-deoxychorismate synthase activity	4.48164623771604	bayes_pls_golite062009
anthranilate synthase activity	2.51214170411838	bayes_pls_golite062009
ligase activity	1.70348758031146	bayes_pls_golite062009
phosphoribosylformylglycinamidine synthase activity	1.51568729563523	bayes_pls_golite062009
oxo-acid-lyase activity	1.35896725827905	bayes_pls_golite062009
catalytic activity	1.30391542469987	bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity	0.270391651600004	bayes_pls_golite062009
nucleic acid binding	0.12569720972861	bayes_pls_golite062009
carbon-carbon lyase activity	0.0769356405014503	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: