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View Structure Prediction Details

Protein: gi|220949268, gi...
Organism: synthetic construct
Length: 157 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220949268, gi....

Description E-value Query
Range		 Subject
Range
gi|25012683 - gi|25012683|gb|AAN71436.1| RE56164p [Drosophila melanogaster]
 180.0 [0..1] [157..10]
NPC2_BOVIN - Epididymal secretory protein E1 OS=Bos taurus GN=NPC2 PE=1 SV=1
 171.0 [0..4] [155..1]
gi|74212648 - gi|74212648|dbj|BAE31061.1| unnamed protein product [Mus musculus]
 165.0 [0..4] [156..1]
gi|27465565, gi|... - gi|34786047|gb|AAH58132.1| Niemann-Pick disease, type C2 [Rattus norvegicus], gi|27465565|ref|NP_775...
 161.0 [0..4] [155..1]
gi|62896507 - gi|62896507|dbj|BAD96194.1| Niemann-Pick disease, type C2 precursor variant [Homo sapiens]
 159.0 [0..18] [156..16]

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Predicted Domain #1
Region A:
Residues: [1-157] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLSSLLPV AFALVLSSVS AEIVNFQTCE DSVDSCSISQ VRVTPCPEAN ANAACHIRRR  60
   61 HRFTMSFDFT PHFDADTLVA SLGWAKSENV ELPLLTMDQE ACKYTTCPVR SGVTQTYTNN 120
  121 MPADARFPLS PYTIRWALKD PVSQKRCCFT IDIKVVR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.69897
Match: 1nepA
Description: Epididymal secretory protein E1 (Niemann-Pick C2 protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.879052093832773 bayes_pls_golite062009
protein binding 0.80731472263402 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle