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View Structure Prediction Details

Protein: gi|220950426
Organism: synthetic construct
Length: 343 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220950426.

Description E-value Query
Range
Subject
Range
CTU1_AEDAE - Cytoplasmic tRNA 2-thiolation protein 1 OS=Aedes aegypti GN=AAEL011283 PE=3 SV=1
271.0 [0..1] [343..1]

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Predicted Domain #1
Region A:
Residues: [1-343]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHIICKSQCG NRAALKRPKT GDALCKECFF AAFEAEIHHT ISSSNLFRRG EKVAVAASGG  60
   61 KDSTVLAHVL KLLNERHNYG LELVLLSIDE GITGYRDDSL ETVKQNRDDY QMPLKILSYE 120
  121 ELYGWTMDRI VAQIGRSNNC TFCGVFRRQA LDRGAKLLGV DSIATGHNAD DIAETVLMNV 180
  181 LRGDTARLRR CTSIRTGGGE DTIPRVKPLK YSYEKEIVMY AHYKKLVYFS TECVFAPNAY 240
  241 RGHARAFLKD LEKVRPSVIM DIIYSGEQLR FKDTVKKPER GTCTRCGFVS SQQPCKACVL 300
  301 LEGLNRGLPK LGIGKKSKGE RMIAKQNQEL ALRERANLVK NDF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.39794
Match: 1gpmA
Description: GMP synthetase; GMP synthetase, central domain; GMP synthetase C-terminal dimerisation domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-nitrogen bonds 4.5241303311086 bayes_pls_golite062009
ligase activity 3.71561290487771 bayes_pls_golite062009
DNA binding 1.07561751049838 bayes_pls_golite062009
nucleic acid binding 1.0681685328021 bayes_pls_golite062009
binding 0.915602461727954 bayes_pls_golite062009
catalytic activity 0.828867994386867 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.475055910258246 bayes_pls_golite062009
transferase activity 0.0776944314618701 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle