YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|170129515, gi...
Organism:	Bacillus anthracis str. A0389
Length:	401 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|170129515, gi....

Description	E-value	Query Range	Subject Range
ASSY_BACCN - Argininosuccinate synthase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391...	0.0	[1..401]	[1..401]
ASSY_BACCZ - Argininosuccinate synthase OS=Bacillus cereus (strain ZK / E33L) GN=argG PE=3 SV=1 gi\|196025249, gi... - gi\|196043913\|ref\|ZP_03111150.1\| argininosuccinate synthase [Bacillus cereus 03BB108], gi\|196025249\|g... ASSY_BACC3 - Argininosuccinate synthase OS=Bacillus cereus (strain 03BB102) GN=argG PE=3 SV=1 ASSY_BACAH - Argininosuccinate synthase OS=Bacillus thuringiensis (strain Al Hakam) GN=argG PE=3 SV=2	0.0	[1..401]	[1..401]
ASSY_BACHD - Argininosuccinate synthase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM... ASSY_BACHD - Argininosuccinate synthase OS=Bacillus halodurans GN=argG PE=3 SV=1	0.0	[1..395]	[1..395]
ASSY_BACC4 - Argininosuccinate synthase OS=Bacillus cereus (strain B4264) GN=argG PE=3 SV=1 gi\|206969614, gi... - gi\|206969614\|ref\|ZP_03230568.1\| argininosuccinate synthase [Bacillus cereus AH1134], gi\|206735302\|gb... ASSY_BACCR - Argininosuccinate synthase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / ... gi\|229112095, gi... - gi\|229112095\|ref\|ZP_04241638.1\| Argininosuccinate synthase [Bacillus cereus Rock1-15], gi\|228671418\|... gi\|228630644, gi... - gi\|229152824\|ref\|ZP_04281007.1\| Argininosuccinate synthase [Bacillus cereus m1550], gi\|228630644\|gb\|...	0.0	[1..401]	[1..401]
ASSY_BACHK - Argininosuccinate synthase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=argG PE=3 SV... ASSY_BACHK - Argininosuccinate synthase OS=Bacillus thuringiensis subsp. konkukian GN=argG PE=3 SV=1	0.0	[1..401]	[1..401]
gi\|74492538, gi\|... - gi\|75759980\|ref\|ZP_00740048.1\| Argininosuccinate synthase [Bacillus thuringiensis serovar israelensi... gi\|228856431, gi... - gi\|228903149\|ref\|ZP_04067283.1\| Argininosuccinate synthase [Bacillus thuringiensis IBL 4222], gi\|228...	0.0	[1..401]	[11..411]
ASSY_BACC1 - Argininosuccinate synthase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=argG PE=3 SV=1	0.0	[1..401]	[1..401]
gi\|47565044, gi\|... - gi\|47565044\|ref\|ZP_00236087.1\| argininosuccinate synthase [Bacillus cereus G9241], gi\|47557830\|gb\|EA...	0.0	[1..401]	[1..401]
gi\|254826266 - gi\|254826266\|ref\|ZP_05231267.1\| argininosuccinate synthase [Listeria monocytogenes FSL J1-194] ASSY_LISMC - Argininosuccinate synthase OS=Listeria monocytogenes serotype 4b (strain Clip81459) GN=argG PE=3 SV=... gi\|254879730 - gi\|254879730\|ref\|ZP_05252440.1\| argininosuccinate synthase [Listeria monocytogenes FSL J2-071] gi\|254854078 - gi\|254854078\|ref\|ZP_05243426.1\| argininosuccinate synthase [Listeria monocytogenes FSL R2-503] gi\|153167967, gi... - gi\|254871759\|ref\|ZP_05244469.1\| argininosuccinate synthase [Listeria monocytogenes FSL N1-017], gi\|1... gi\|153203193, gi... - gi\|254931801\|ref\|ZP_05265160.1\| argininosuccinate synthase [Listeria monocytogenes HPB2262], gi\|1532... gi\|255520760 - gi\|255520760\|ref\|ZP_05387997.1\| argininosuccinate synthase [Listeria monocytogenes FSL J1-175] ASSY_LISMC - Argininosuccinate synthase OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=argG PE=3 SV=... ASSY_LISMH - Argininosuccinate synthase OS=Listeria monocytogenes serotype 4a (strain HCC23) GN=argG PE=3 SV=1 gi\|224498464 - gi\|224498464\|ref\|ZP_03666813.1\| argininosuccinate synthase [Listeria monocytogenes Finland 1988] ASSY_LISMF - Argininosuccinate synthase OS=Listeria monocytogenes serotype 4b (strain F2365) GN=argG PE=3 SV=1 gi\|47091758, gi\|... - gi\|47091758\|ref\|ZP_00229553.1\| argininosuccinate synthase [Listeria monocytogenes str. 4b H7858], gi...	0.0	[1..397]	[1..397]
ASSY_OCEIH - Argininosuccinate synthase OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / H... ASSY_OCEIH - Argininosuccinate synthase OS=Oceanobacillus iheyensis GN=argG PE=3 SV=1	0.0	[1..400]	[1..401]

Back

Predicted Domain #1

Region A:
Residues: [1-401]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKKKVVLAY SGGLDTSVAI KWLQEKNYDI IALCLDLGEG KDLAFVKEKA LSVGAIKSYM  60
   61 IDVQEEFANE YALMAMQAHT LYEGKYPLVS ALSRPLIAKK LVEIAEQEGA TAVAHGCTGK 120
  121 GNDQVRFEVS IQALNPYLEV IAPVREWKWS REEEIAYAKE NNVPIPINLD SPFSIDQNLW 180
  181 GRSNECGILE DPWAAPPEDA YEMTLALEDT PNKPEFVEIG FEAGVPTTLN GTAYPLSELI 240
  241 KTLNALAGKH GVGRIDHVEN RLVGIKSREV YECPAAMTLI TAHKELEDLT LVKEVAHFKP 300
  301 MIEQKITELI YNGLWFSPLK QALHAFLQET QKNVTGTVRV KLFKGHAIVE GRKSEYSLYD 360
  361 EKLATYTAQD EFNHDAAVGF ISLFGLPTKV YSQVNQKKVE A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	121.0
Match:	1j1zA
Description:	Argininosuccinate synthetase, N-terminal domain; Argininosuccinate synthetase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
argininosuccinate synthase activity	5.55984418125277	bayes_pls_golite062009
ligase activity	2.54636182867584	bayes_pls_golite062009
catalytic activity	1.4716728594386	bayes_pls_golite062009
binding	0.949267645607863	bayes_pls_golite062009
protein binding	0.476576076629648	bayes_pls_golite062009
asparagine synthase (glutamine-hydrolyzing) activity	0.3673193848392	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.204705463374024	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: