YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|170083613, gi...
Organism:	Escherichia coli str. K-12 substr. DH10B
Length:	515 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|170083613, gi....

Description	E-value	Query Range	Subject Range
gi\|81248004, gi\|... - gi\|82546593\|ref\|YP_410539.1\| hypothetical protein SBO_4290 [Shigella boydii Sb227], gi\|81248004\|gb\|A...	457.0	[0..1]	[515..1]
gi\|75179462, gi\|... - gi\|75179462\|ref\|ZP_00699466.1\| COG0063: Predicted sugar kinase [Shigella boydii BS512], gi\|187733105...	457.0	[0..1]	[515..1]
gi\|110617632, gi... - gi\|110808084\|ref\|YP_691605.1\| hypothetical protein SFV_4324 [Shigella flexneri 5 str. 8401], gi\|1106...	457.0	[0..1]	[515..1]
gi\|73858128, gi\|... - gi\|74314651\|ref\|YP_313071.1\| hypothetical protein SSON_4351 [Shigella sonnei Ss046], gi\|73858128\|gb\|...	455.0	[0..1]	[515..1]
gi\|56480583, gi\|... - gi\|56480583\|ref\|NP_710032.2\| hypothetical protein SF4321 [Shigella flexneri 2a str. 301], gi\|5638413...	454.0	[0..1]	[515..1]
gi\|188490428, gi... - gi\|75515406\|ref\|ZP_00737563.1\| COG0063: Predicted sugar kinase [Escherichia coli 53638], gi\|18849522...	454.0	[0..1]	[515..1]
gi\|91213716, gi\|... - gi\|91213716\|ref\|YP_543702.1\| hypothetical protein UTI89_C4767 [Escherichia coli UTI89], gi\|91075290\|... gi\|26111491, gi\|... - gi\|26251059\|ref\|NP_757099.1\| hypothetical protein c5251 [Escherichia coli CFT073], gi\|26111491\|gb\|AA... gi\|226901745, gi... - gi\|237703833\|ref\|ZP_04534314.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|218430065, gi... - gi\|218692501\|ref\|YP_002400713.1\| hypothetical protein ECED1_4952 [Escherichia coli ED1a], gi\|2184300...	454.0	[0..1]	[515..8]
gi\|30065539, gi\|... - gi\|30065539\|ref\|NP_839710.1\| hypothetical protein S4589 [Shigella flexneri 2a str. 2457T], gi\|300438...	453.0	[0..1]	[515..1]
gi\|218561326, gi... - gi\|218561326\|ref\|YP_002394239.1\| hypothetical protein ECS88_4753 [Escherichia coli S88], gi\|21836809... gi\|227836363, gi... - gi\|227886790\|ref\|ZP_04004595.1\| possible sugar kinase [Escherichia coli 83972], gi\|227836363\|gb\|EEJ4... gi\|110346116, gi... - gi\|110644524\|ref\|YP_672254.1\| hypothetical protein ECP_4412 [Escherichia coli 536], gi\|110346116\|gb\|... gi\|117626514, gi... - gi\|117626514\|ref\|YP_859837.1\| hypothetical protein APECO1_2224 [Escherichia coli APEC O1], gi\|115515...	452.0	[0..1]	[515..1]
gi\|75236180 - gi\|75236180\|ref\|ZP_00720302.1\| COG0063: Predicted sugar kinase [Escherichia coli F11]	452.0	[0..1]	[515..1]

Back

Predicted Domain #1

Region A:
Residues: [1-515]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDHTMKKNP VSIPHTVWYA DDIRRGEREA ADVLGLTLYE LMLRAGEAAF QVCRSAYPDA  60
   61 RHWLVLCGHG NNGGDGYVVA RLAKAVGIEV TLLAQESDKP LPEEAALARE AWLNAGGEIH 120
  121 ASNIVWPESV DLIVDALLGT GLRQAPRESI SQLIDHANSH PAPIVAVDIP SGLLAETGAT 180
  181 PGAVINADHT ITFIALKPGL LTGKARDVTG QLHFDSLGLD SWLAGQETKI QRFSAEQLSH 240
  241 WLKPRRPTSH KGDHGRLVII GGDHGTAGAI RMTGEAALRA GAGLVRVLTR SENIAPLLTA 300
  301 RPELMVHELT MDSLTESLEW ADVVVIGPGL GQQEWGKKAL QKVENFRKPM LWDADALNLL 360
  361 AINPDKRHNR VITPHPGEAA RLLGCSVAEI ESDRLHCAKR LVQRYGGVAV LKGAGTVVAA 420
  421 HPDALGIIDA GNAGMASGGM GDVLSGIIGA LLGQKLSPYD AACAGCVAHG AAADVLAARF 480
  481 GTRGMLATDL FSTLQRIVNP EVTDKNHDES SNSAP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	94.30103
Match:	2ax3A
Description:	Crystal structure of hypothetical protein (tm0922) from THERMOTOGA MARITIMA at 2.27 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.74474587246986	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.47090819518452	bayes_pls_golite062009
kinase activity	1.44473837278874	bayes_pls_golite062009
transferase activity	1.38207816260569	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: