YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|168781731, gi...
Organism:	Escherichia coli O157:H7 str. EC4076
Length:	382 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168781731, gi....

Description	E-value	Query Range	Subject Range
CARA_SALTY - Carbamoyl-phosphate synthase small chain OS=Salmonella typhimurium GN=carA PE=3 SV=2 CARA_SALTY - Carbamoyl-phosphate synthase small chain OS=Salmonella typhimurium GN=carA PE=3 SV=2 gi\|167989924, gi... - gi\|205331492\|gb\|EDZ18256.1\| carbamoyl-phosphate synthase, small subunit [Salmonella enterica subsp. ... gi\|197264738, gi... - gi\|197264738\|ref\|ZP_03164812.1\| carbamoyl-phosphate synthase, small subunit [Salmonella enterica sub... lcl\|NC_016856.1_... - [gene=carA] [protein=carbamoyl phosphate synthase small subunit] [protein_id=YP_005235710.1] [locati... CARA_SALTY - Carbamoyl-phosphate synthase small chain OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700...	502.0	[0..1]	[382..1]
gi\|62126263, gi\|... - gi\|62178630\|ref\|YP_215047.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subsp. ...	502.0	[0..1]	[382..1]
gi\|29136233, gi\|... - gi\|29140609\|ref\|NP_803951.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subsp. ... gi\|213650150 - gi\|213650150\|ref\|ZP_03380203.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subs... gi\|214001274 - gi\|214001274\|ref\|ZP_03412009.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subs... gi\|213419769 - gi\|213419769\|ref\|ZP_03352835.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subs... gi\|213427506 - gi\|213427506\|ref\|ZP_03360256.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subs... gi\|213163013 - gi\|213163013\|ref\|ZP_03348723.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subs...	501.0	[0..1]	[382..1]
gi\|56412338, gi\|... - gi\|56412338\|ref\|YP_149413.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subsp. ... gi\|238911125 - gi\|238911125\|ref\|ZP_04654962.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subs... gi\|197361275, gi... - gi\|197361275\|ref\|YP_002140910.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica sub...	500.0	[0..1]	[382..1]
CARA_ECOL6 - Carbamoyl-phosphate synthase small chain OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UP... gi\|218425471, gi... - gi\|218687907\|ref\|YP_002396119.1\| carbamoyl phosphate synthase small subunit [Escherichia coli ED1a],... gi\|218556970, gi... - gi\|218556970\|ref\|YP_002389883.1\| carbamoyl phosphate synthase small subunit [Escherichia coli S88], ... CARA_ECOL6 - Carbamoyl-phosphate synthase small chain OS=Escherichia coli O6 GN=carA PE=3 SV=2	500.0	[0..1]	[382..1]
gi\|4929942, gi\|4... - gi\|5821983\|pdb\|1CE8\|H Chain H, Carbamoyl Phosphate Synthetase From Escherichis Coli With Complexed W...	500.0	[0..1]	[382..1]
gi\|190905613, gi... - gi\|191174119\|ref\|ZP_03035633.1\| carbamoyl-phosphate synthase, small subunit [Escherichia coli F11], ... gi\|110341836, gi... - gi\|110640244\|ref\|YP_667972.1\| carbamoyl phosphate synthase small subunit [Escherichia coli 536], gi\|...	500.0	[0..1]	[382..1]
CARA_SALTI - Carbamoyl-phosphate synthase small chain OS=Salmonella typhi GN=carA PE=3 SV=1 CARA_SALTI - Carbamoyl-phosphate synthase small chain OS=Salmonella typhi GN=carA PE=3 SV=1 gi\|16759059 - gi\|16759059\|ref\|NP_454676.1\| carbamoyl phosphate synthase small subunit [Salmonella enterica subsp. ...	500.0	[0..1]	[382..1]
gi\|110613647, gi... - gi\|110804099\|ref\|YP_687619.1\| carbamoyl phosphate synthase small subunit [Shigella flexneri 5 str. 8... gi\|56383139, gi\|... - gi\|56479588\|ref\|NP_705988.2\| carbamoyl phosphate synthase small subunit [Shigella flexneri 2a str. 3... gi\|30039842, gi\|... - gi\|30061600\|ref\|NP_835771.1\| carbamoyl phosphate synthase small subunit [Shigella flexneri 2a str. 2...	499.0	[0..1]	[382..1]

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Predicted Domain #1

Region A:
Residues: [1-382]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKSALLVLE DGTQFHGRAI GATGSAVGEV VFNTSMTGYQ EILTDPSYSR QIVTLTYPHI  60
   61 GNVGTNDADE ESSQVHAQGL VIRDLPLIAS NFRNTEDLSS YLKRHNIVAI ADIDTRKLTR 120
  121 LLREKGAQNG CIIAGDNPDA ALALEKARAF PGLNGMDLAK EVTTAEAYSW TQGSWTLTGG 180
  181 LPEAKKEDEL PFHVVAYDFG AKRNILRMLV DRGCRLTIVP AQTSAEDVLK MNPDGIFLSN 240
  241 GPGDPAPCDY AITAIQKFLE TDIPVFGICL GHQLLALASG AKTVKMKFGH HGGNHPVKDV 300
  301 EKNVVMITAQ NHGFAVDEAT LPANLRVTHK SLFDGTLQGI HRTDKPAFSF QGHPEASPGP 360
  361 HDAAPLFDHF IELIEQYRKT AK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	142.0
Match:	1bxrB
Description:	Carbamoyl phosphate synthetase, small subunit N-terminal domain; Carbamoyl phosphate synthetase, small subunit C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	9.74519370915839	bayes_pls_golite062009
carbamoyl-phosphate synthase activity	9.70414577567935	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	9.14496558670743	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	7.05319676113266	bayes_pls_golite062009
4-amino-4-deoxychorismate synthase activity	4.48164623771604	bayes_pls_golite062009
anthranilate synthase activity	2.51214170411838	bayes_pls_golite062009
ligase activity	1.70348758031146	bayes_pls_golite062009
phosphoribosylformylglycinamidine synthase activity	1.51568729563523	bayes_pls_golite062009
oxo-acid-lyase activity	1.35896725827905	bayes_pls_golite062009
catalytic activity	1.30391542469987	bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity	0.270391651600004	bayes_pls_golite062009
nucleic acid binding	0.12569720972861	bayes_pls_golite062009
carbon-carbon lyase activity	0.0769356405014503	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: