YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213427457
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E02-1180
Length:	483 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213427457.

Description	E-value	Query Range	Subject Range
lcl\|NC_016856.1_... - [gene=yieM] [protein=hypothetical protein] [protein_id=YP_005240147.1] [location=complement(4099998.... VIAA_SALPB - Protein ViaA OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=viaA PE=3 SV=1 gi\|238913131 - gi\|238913131\|ref\|ZP_04656968.1\| hypothetical protein SentesTe_18660 [Salmonella enterica subsp. ente... VIAA_SALPB - Protein viaA OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=viaA PE=3 SV=1 VIAA_SALTY - Protein ViaA OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=viaA PE=3 SV=2 VIAA_SALTY - Protein viaA OS=Salmonella typhimurium GN=viaA PE=3 SV=2 VIAA_SALDC - Protein ViaA OS=Salmonella dublin (strain CT_02021853) GN=viaA PE=3 SV=1 gi\|197264726, gi... - gi\|197264726\|ref\|ZP_03164800.1\| protein ViaA [Salmonella enterica subsp. enterica serovar Saintpaul ... gi\|168823145, gi... - gi\|205340566\|gb\|EDZ27330.1\| protein ViaA [Salmonella enterica subsp. enterica serovar Weltevreden st... gi\|168234390, gi... - gi\|205331683\|gb\|EDZ18447.1\| protein ViaA [Salmonella enterica subsp. enterica serovar Kentucky str. ... gi\|194459328, gi... - gi\|194472964\|ref\|ZP_03078948.1\| protein ViaA [Salmonella enterica subsp. enterica serovar Kentucky s... VIAA_SALTY - Protein viaA OS=Salmonella typhimurium GN=viaA PE=3 SV=2 VIAA_SALNS - Protein ViaA OS=Salmonella newport (strain SL254) GN=viaA PE=3 SV=1 gi\|205327322, gi... - gi\|205327322\|gb\|EDZ14086.1\| protein ViaA [Salmonella enterica subsp. enterica serovar 4,[5],12:i:- s...	0.0	[1..473]	[1..473]
gi\|193063846, gi... - gi\|75258284\|ref\|ZP_00729732.1\| COG2425: Uncharacterized protein containing a von Willebrand factor t... VIAA_ECOBW - Protein ViaA OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=viaA PE=3 SV=1 YIEM_ECOLI, VIAA... - (P03818) Hypothetical protein yieM, Protein viaA (VWA domain protein interacting with AAA ATPase) - ... gi\|85676293, gi\|... - gi\|89110262\|ref\|AP_004042.1\| predicted von Willibrand factor containing protein [Escherichia coli st... gi\|254595151, gi... - gi\|254795751\|ref\|YP_003080588.1\| Von Willebrand Factor Type A (VWA) domain-containing protein [Esche... EG11730 - stimulator of RavA ATPase activity; von Willebrand factor domain protein / Stimulator of RavA ATPase... gi\|75210645, gi\|... - gi\|75210645\|ref\|ZP_00710786.1\| COG2425: Uncharacterized protein containing a von Willebrand factor t... gi\|192955077, gi... - gi\|75214829\|ref\|ZP_00713314.1\| COG2425: Uncharacterized protein containing a von Willebrand factor t... VIAA_SHISS - Protein ViaA OS=Shigella sonnei (strain Ss046) GN=viaA PE=3 SV=1 gi\|13364162, gi\|... - gi\|15833941\|ref\|NP_312714.1\| hypothetical protein ECs4687 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|161367484 - gi\|161367484\|ref\|NP_290384.2\| hypothetical protein Z5246 [Escherichia coli O157:H7 EDL933] VIAA_ECODH - Protein ViaA OS=Escherichia coli (strain K12 / DH10B) GN=viaA PE=3 SV=1 gi\|189376775, gi... - gi\|189376775\|gb\|EDU95191.1\| ViaA family protein [Escherichia coli O157:H7 str. EC508], gi\|168800970\|... gi\|208806093, gi... - gi\|208806093\|ref\|ZP_03248430.1\| ViaA family protein [Escherichia coli O157:H7 str. EC4206], gi\|20872... gi\|195936372 - gi\|195936372\|ref\|ZP_03081754.1\| hypothetical protein EscherichcoliO157_07898 [Escherichia coli O157:... gi\|208739754, gi... - gi\|208819631\|ref\|ZP_03259951.1\| ViaA family protein [Escherichia coli O157:H7 str. EC4042], gi\|20873... gi\|208813494, gi... - gi\|208813494\|ref\|ZP_03254823.1\| ViaA family protein [Escherichia coli O157:H7 str. EC4045], gi\|20873... gi\|217326209, gi... - gi\|217326209\|ref\|ZP_03442293.1\| ViaA family protein [Escherichia coli O157:H7 str. TW14588], gi\|2173... VIAA_ECO5E - Protein ViaA OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=viaA PE=3 SV=1 gi\|168752411, gi... - gi\|188013744\|gb\|EDU51866.1\| ViaA family protein [Escherichia coli O157:H7 str. EC4113], gi\|168752411... gi\|161984822 - gi\|161984822\|ref\|YP_410042.2\| hypothetical protein SBO_3742 [Shigella boydii Sb227] gi\|189365075, gi... - gi\|189365075\|gb\|EDU83491.1\| ViaA family protein [Escherichia coli O157:H7 str. EC4501], gi\|168765051... gi\|168753647, gi... - gi\|189359152\|gb\|EDU77571.1\| ViaA family protein [Escherichia coli O157:H7 str. EC4401], gi\|168753647... gi\|187766978, gi... - gi\|187766978\|gb\|EDU30822.1\| ViaA family protein [Escherichia coli O157:H7 str. EC4196], gi\|168777889... gi\|189362730, gi... - gi\|189362730\|gb\|EDU81149.1\| ViaA family protein [Escherichia coli O157:H7 str. EC4486], gi\|168768031... gi\|189373324, gi... - gi\|189373324\|gb\|EDU91740.1\| ViaA family protein [Escherichia coli O157:H7 str. EC869], gi\|168786588\|... gi\|168780649, gi... - gi\|189001501\|gb\|EDU70487.1\| ViaA family protein [Escherichia coli O157:H7 str. EC4076], gi\|168780649... VIAA_ECO57 - Protein ViaA OS=Escherichia coli O157:H7 GN=viaA PE=3 SV=1 VIAA_ECO8A - Protein ViaA OS=Escherichia coli O8 (strain IAI1) GN=viaA PE=3 SV=1 EG11730 - stimulator of RavA ATPase activity; von Willebrand factor domain protein / Stimulator of RavA ATPase...	0.0	[1..473]	[1..473]
gi\|124499446, gi... - gi\|124530041\|ref\|ZP_01700824.1\| von Willebrand factor, type A [Escherichia coli B], gi\|124499446\|gb\|... VIAA_ECOHS - Protein ViaA OS=Escherichia coli O9:H4 (strain HS) GN=viaA PE=3 SV=1 gi\|242379283, gi... - gi\|251787010\|ref\|YP_003001314.1\| hypothetical protein B21_03573 [Escherichia coli BL21], gi\|24237928... gi\|83588390, gi\|... - gi\|83588390\|ref\|ZP_00927014.1\| COG2425: Uncharacterized protein containing a von Willebrand factor t... gi\|254163696, gi... - gi\|254163696\|ref\|YP_003046804.1\| predicted von Willibrand factor containing protein [Escherichia col... VIAA_ECOLC - Protein ViaA OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=viaA PE=3 SV=1 gi\|254290447, gi... - gi\|254290447\|ref\|YP_003056195.1\| predicted von Willibrand factor containing protein [Escherichia col...	0.0	[1..473]	[1..473]
VIAA_SALPC - Protein ViaA OS=Salmonella paratyphi C (strain RKS4594) GN=viaA PE=3 SV=1 VIAA_SALCH - Protein viaA OS=Salmonella choleraesuis GN=viaA PE=3 SV=1 VIAA_SALCH - Protein ViaA OS=Salmonella choleraesuis (strain SC-B67) GN=viaA PE=3 SV=1 VIAA_SALCH - Protein viaA OS=Salmonella choleraesuis GN=viaA PE=3 SV=1	0.0	[1..473]	[1..473]
VIAA_SALPA - Protein viaA OS=Salmonella paratyphi A GN=viaA PE=3 SV=1 VIAA_SALPA - Protein ViaA OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=viaA PE=3 SV=1	0.0	[1..473]	[1..473]
gi\|75242467, gi\|... - gi\|75242467\|ref\|ZP_00726211.1\| COG2425: Uncharacterized protein containing a von Willebrand factor t... VIAA_ECOL5 - Protein ViaA OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=viaA PE=3 SV=1	0.0	[1..473]	[1..473]
VIAA_ECO45 - Protein ViaA OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=viaA PE=3 SV=1 gi\|237703546, gi... - gi\|237703546\|ref\|ZP_04534027.1\| viaA [Escherichia sp. 3_2_53FAA], gi\|226902810\|gb\|EEH89069.1\| viaA [... VIAA_ECOUT - Protein ViaA OS=Escherichia coli (strain UTI89 / UPEC) GN=viaA PE=3 SV=1 VIAA_ECOL6 - Protein ViaA OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=viaA PE=3 SV=1 VIAA_ECOL6 - Protein viaA OS=Escherichia coli O6 GN=viaA PE=3 SV=1 VIAA_ECOK1 - Protein ViaA OS=Escherichia coli O1:K1 / APEC GN=viaA PE=3 SV=1	0.0	[1..473]	[1..473]
VIAA_SHIB3 - Protein ViaA OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=viaA PE=3 SV=1	0.0	[1..473]	[1..473]
gi\|188487291, gi... - gi\|75514189\|ref\|ZP_00736497.1\| COG2425: Uncharacterized protein containing a von Willebrand factor t...	0.0	[1..473]	[1..473]
gi\|191169199, gi... - gi\|75227514\|ref\|ZP_00714275.1\| COG2425: Uncharacterized protein containing a von Willebrand factor t... VIAA_ECO24 - Protein ViaA OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=viaA PE=3 SV=1 VIAA_ECOSE - Protein ViaA OS=Escherichia coli (strain SE11) GN=viaA PE=3 SV=1	0.0	[1..473]	[1..473]

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Predicted Domain #1

Region A:
Residues: [1-117]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTLDTLNTM LAVSEEGMVE EMILALLASP QLVIFFEKFP RLKNAVTADL PRWREALRSR  60
   61 LKDARVPPEL TEEVMCYQQS QLLSTPQFIV QLPQILALLH RLHSPYAAQA KQLTESN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.810	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin

Predicted Domain #2

Region A:
Residues: [118-483]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STFTPALHTL FLQRWRLSLV VQATTLNQQL LEEEREQLLS DVQERMTLSG QLEPTLAEND  60
   61 NAAGRLWDMS AGQLKRGDYQ LIVKYGEFLA AQPELMQLAE QLGRSREAKS VPKKDAPMET 120
  121 FRTLVREPAT VPEQVDGIQQ GDDILRLLPP ELATLGITEL EYEFYRRLVE KQLLTYRLHG 180
  181 EAWREKVTER PVVHQDVDEQ PRGPFIVCVD TSGSMGGFNE QCAKAFCLAL MRVALADNRR 240
  241 CFIMLFSTDV VRYELSGPES IEQAIRFLSQ RFRGGTDIAS CFRAIIERMQ GREWFDADAV 300
  301 VISDFIAQRL PDDVVSKVGE LQRLHQHRFH AVAMSAHGKP GIMRIFDHIW RFDTGMRSRL 360
  361 LRRWRR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.045757
Match:	1yvpA
Description:	Ro autoantigen complexed with RNAs
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.478378407636654	bayes_pls_golite062009
protein binding	0.0696520417739894	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: