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View Structure Prediction Details

Protein: gi|213163504
Organism: Salmonella enterica subsp. enterica serovar Typhi str. E00-7866
Length: 300 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213163504.

Description E-value Query
Range
Subject
Range
gi|114590613 - gi|114590613|ref|XP_516898.2| PREDICTED: methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) [Pan trogl...
6.0E-68 [2..300] [182..510]
gi|109043037 - gi|109043037|ref|XP_001096717.1| PREDICTED: similar to methylcrotonoyl-Coenzyme A carboxylase 1 (alp...
2.0E-67 [2..299] [123..448]
gi|62089054 - gi|62089054|dbj|BAD92974.1| methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) variant [Homo sapiens]
5.0E-67 [2..300] [67..395]
gi|76670627 - gi|76670627|ref|XP_591194.2| PREDICTED: similar to methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) ...
1.0E-66 [2..300] [51..379]

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Predicted Domain #1
Region A:
Residues: [1-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIAILSRDG TLYSCKRLRE AAMRRGHLVE ILDPLSCYMN INPAASSIHY KGRRLPHFDA  60
   61 VIPRIGSAIT FYGTAALRQF ELLGSYPLNE SVAITRARDK LRSLQLLARQ GIDLPITGIA 120
  121 HSPDDTSDLI KMVGGAPLVV KLVEGTQGIG VVLAETRQAA ESVIDAFRGL NAHILVQEYI 180
  181 AEAKGCDIRC LVVGNEVVAA IERCAKAGDF RSNLHRGGVA SIATITPRER DIAIKAAQTL 240
  241 GLDVAGVDIL RAARGPLVME VNASPGLEGI EKTTGVDIAG RMIQWIERHA TPEFCLKIGG 300
  301 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.09691
Match: 1bxrA
Description: Carbamoyl phosphate synthetase, large subunit connection domain; Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain; Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains; Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity 2.76972866130423 bayes_pls_golite062009
catalytic activity 2.5009559386228 bayes_pls_golite062009
acid-amino acid ligase activity 0.318415105717148 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.239594107637156 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle