YRC Public Data Repository - Protein Structure Prediction

Protein:	COAA_ECO45
Organism:	Escherichia coli S88
Length:	316 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COAA_ECO45.

Description	E-value	Query Range	Subject Range
COAA_PHOLL - Pantothenate kinase OS=Photorhabdus luminescens subsp. laumondii GN=coaA PE=3 SV=1 COAA_PHOLL - Pantothenate kinase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT...	288.0	[0..1]	[316..1]
gi\|24054556, gi\|... - ref\|NP_709774.1\| rts gene product [Shigella flexneri 2a str. 301], gb\|AAN45481.1\| rts gene product ... gi\|110807829, gi... - gi\|110807829\|ref\|YP_691349.1\| pantothenate kinase [Shigella flexneri 5 str. 8401], gi\|110617377\|gb\|A...	287.0	[0..1]	[316..53]
COAA_SALPB - Pantothenate kinase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=coaA PE=3 SV=1 COAA_SALTY - Pantothenate kinase OS=Salmonella typhimurium GN=coaA PE=3 SV=1 COAA_SALTY - Pantothenate kinase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=coaA PE=3 SV=... COAA_SALPC - Pantothenate kinase OS=Salmonella paratyphi C (strain RKS4594) GN=coaA PE=3 SV=1 COAA_SALTY - Pantothenate kinase OS=Salmonella typhimurium GN=coaA PE=3 SV=1 gi\|205321453, gi... - gi\|205357489\|ref\|ZP_02348072.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Sai... gi\|205326991, gi... - gi\|205358199\|ref\|ZP_02576422.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar 4,[... gi\|205335977, gi... - gi\|205359466\|ref\|ZP_02670230.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Hei... COAA_SALEP - Pantothenate kinase OS=Salmonella enteritidis PT4 (strain P125109) GN=coaA PE=3 SV=1 COAA_SALHS - Pantothenate kinase OS=Salmonella heidelberg (strain SL476) GN=coaA PE=3 SV=1 lcl\|NC_016856.1_... - [gene=coaA] [protein=pantothenate kinase] [protein_id=YP_005240422.1] [location=complement(4372275..... gi\|194458277, gi... - gi\|194471913\|ref\|ZP_03077897.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Ken... COAA_SALDC - Pantothenate kinase OS=Salmonella dublin (strain CT_02021853) GN=coaA PE=3 SV=1 gi\|200388743, gi... - gi\|200388743\|ref\|ZP_03215355.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Vir... COAA_SALCH - Pantothenate kinase OS=Salmonella choleraesuis (strain SC-B67) GN=coaA PE=3 SV=2 COAA_SALPB - Pantothenate kinase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=coaA PE=3 SV=1 COAA_SALCH - Pantothenate kinase OS=Salmonella choleraesuis GN=coaA PE=3 SV=2 gi\|205340453, gi... - gi\|205340453\|gb\|EDZ27217.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Weltevr... COAA_SALCH - Pantothenate kinase OS=Salmonella choleraesuis GN=coaA PE=3 SV=2	285.0	[0..1]	[316..1]
gi\|197239852, gi... - gi\|197266062\|ref\|ZP_03166135.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Sai... gi\|62182597, gi\|... - gi\|62182597\|ref\|YP_219014.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Choler...	285.0	[0..1]	[316..3]
gi\|227837533, gi... - gi\|227885495\|ref\|ZP_04003300.1\| pantothenate kinase [Escherichia coli 83972], gi\|227837533\|gb\|EEJ479... gi\|110644314, gi... - gi\|110644314\|ref\|YP_672044.1\| pantothenate kinase [Escherichia coli 536], gi\|110345906\|gb\|ABG72143.1... gi\|26250747, gi\|... - gi\|26250747\|ref\|NP_756787.1\| pantothenate kinase [Escherichia coli CFT073], gi\|26111178\|gb\|AAN83361.... gi\|115515367, gi... - gi\|117626243\|ref\|YP_859566.1\| pantothenate kinase [Escherichia coli APEC O1], gi\|115515367\|gb\|ABJ034... gi\|91074354, gi\|... - gi\|91212780\|ref\|YP_542766.1\| pantothenate kinase [Escherichia coli UTI89], gi\|91074354\|gb\|ABE09235.1... gi\|124497994, gi... - gi\|124532579\|ref\|ZP_01702258.1\| pantothenate kinase [Escherichia coli B], gi\|124497994\|gb\|EAY45534.1...	285.0	[0..1]	[316..8]
COAA_SHIDS - Pantothenate kinase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=coaA PE=3 SV=1	284.0	[0..1]	[316..1]
COAA_SALTI - Pantothenate kinase OS=Salmonella typhi GN=coaA PE=3 SV=1 gi\|213999715 - gi\|213999715\|ref\|ZP_03410450.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typ... COAA_SALA4 - Pantothenate kinase OS=Salmonella agona (strain SL483) GN=coaA PE=3 SV=1 COAA_SALPK - Pantothenate kinase OS=Salmonella paratyphi A (strain AKU_12601) GN=coaA PE=3 SV=1 gi\|205360640, gi... - gi\|205360640\|ref\|ZP_02684926.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Had... gi\|213163738 - gi\|213163738\|ref\|ZP_03349448.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typ... gi\|168468124, gi... - gi\|195628796\|gb\|EDX48226.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Newport... COAA_SALPA - Pantothenate kinase OS=Salmonella paratyphi A GN=coaA PE=3 SV=1 COAA_SALNS - Pantothenate kinase OS=Salmonella newport (strain SL254) GN=coaA PE=3 SV=1 COAA_SALSV - Pantothenate kinase OS=Salmonella schwarzengrund (strain CVM19633) GN=coaA PE=3 SV=1 gi\|16762309 - gi\|16762309\|ref\|NP_457926.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typhi ... COAA_SALTI - Pantothenate kinase OS=Salmonella typhi GN=coaA PE=3 SV=1 COAA_SALPA - Pantothenate kinase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=coaA PE=3 SV=1 gi\|29139432, gi\|... - gi\|29143797\|ref\|NP_807139.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typhi ...	284.0	[0..1]	[316..1]
COAA_SHIFL - Pantothenate kinase OS=Shigella flexneri GN=coaA PE=3 SV=2	284.0	[0..1]	[316..1]
gi\|226903057, gi... - gi\|237702744\|ref\|ZP_04533225.1\| pantothenate kinase [Escherichia sp. 3_2_53FAA], gi\|226903057\|gb\|EEH... gi\|254039233, gi... - gi\|254039233\|ref\|ZP_04873282.1\| pantothenate kinase [Escherichia sp. 1_1_43], gi\|226838468\|gb\|EEH704... gi\|147780 - gi\|147780\|gb\|AAA76838.1\| rts [Escherichia coli]	283.0	[0..1]	[316..21]
gi\|229706564, gi... - gi\|229836496\|ref\|ZP_04456663.1\| pantothenate kinase [Yersinia pestis Pestoides A], gi\|229706564\|gb\|E... COAA_YERPS - Pantothenate kinase OS=Yersinia pseudotuberculosis GN=coaA PE=3 SV=1 gi\|229695807, gi... - gi\|229839441\|ref\|ZP_04459600.1\| pantothenate kinase [Yersinia pestis biovar Orientalis str. PEXU2], ... gi\|229686948, gi... - gi\|229900004\|ref\|ZP_04515142.1\| pantothenate kinase [Yersinia pestis biovar Orientalis str. India 19... gi\|149289316, gi... - gi\|153997208\|ref\|ZP_02022315.1\| pantothenate kinase [Yersinia pestis CA88-4125], gi\|149289316\|gb\|EDM... COAA_YERPP - Pantothenate kinase OS=Yersinia pestis (strain Pestoides F) GN=coaA PE=3 SV=1 COAA_YERPE - Pantothenate kinase OS=Yersinia pestis GN=coaA PE=3 SV=1 COAA_YERPG - Pantothenate kinase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=coaA PE=3 SV=1 COAA_YERP3 - Pantothenate kinase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=coaA PE=3 SV=1 COAA_YERPA - Pantothenate kinase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=coaA PE=3 SV=1 COAA_YERPN - Pantothenate kinase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=coaA PE=3 SV=1 COAA_YERPB - Pantothenate kinase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=coaA PE=3 SV=1 gi\|165912058, gi... - gi\|89102990\|ref\|ZP_01175588.1\| COG1072: Panthothenate kinase [Yersinia pestis biovar Orientalis str.... gi\|165988950, gi... - gi\|166012149\|ref\|ZP_02233047.1\| pantothenate kinase [Yersinia pestis biovar Antiqua str. E1979001], ... gi\|165926264, gi... - gi\|165926264\|ref\|ZP_02222096.1\| pantothenate kinase [Yersinia pestis biovar Orientalis str. F1991016... gi\|167399681, gi... - gi\|167399681\|ref\|ZP_02305205.1\| pantothenate kinase [Yersinia pestis biovar Antiqua str. UG05-0454],... gi\|166204188, gi... - gi\|166214625\|ref\|ZP_02240660.1\| pantothenate kinase [Yersinia pestis biovar Antiqua str. B42003004],... gi\|45437908, gi\|... - gi\|45443041\|ref\|NP_994580.1\| pantothenate kinase [Yersinia pestis biovar Microtus str. 91001], gi\|45... gi\|167054182, gi... - gi\|167426800\|ref\|ZP_02318553.1\| pantothenate kinase [Yersinia pestis biovar Mediaevalis str. K197300... gi\|22124388, gi\|... - gi\|22124388\|ref\|NP_667811.1\| pantothenate kinase [Yersinia pestis KIM], gi\|21957169\|gb\|AAM84062.1\|AE... gi\|167422996, gi... - gi\|167422996\|ref\|ZP_02314749.1\| pantothenate kinase [Yersinia pestis biovar Orientalis str. MG05-102... gi\|15981674, gi\|... - gi\|218930763\|ref\|YP_002348638.1\| pantothenate kinase [Yersinia pestis CO92], gi\|16123895\|ref\|NP_4072... COAA_YERPY - Pantothenate kinase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=coaA PE=3 SV=1 COAA_YERPS - Pantothenate kinase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=coaA PE=3 SV=1 gi\|167470585 - gi\|167470585\|ref\|ZP_02335289.1\| pantothenate kinase [Yersinia pestis FV-1]	283.0	[0..1]	[316..1]

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Predicted Domain #1

Region A:
Residues: [1-316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIKEQTLMT PYLQFDRNQW AALRDSVPMT LSEDEIARLK GINEDLSLEE VAEIYLPLSR  60
   61 LLNFYISSNL RRQAVLEQFL GTNGQRIPYI ISIAGSVAVG KSTTARVLQA LLSRWPEHRR 120
  121 VELITTDGFL HPNQVLKERG LMKKKGFPES YDMHRLVKFV SDLKSGVPNV TAPVYSHLIY 180
  181 DVIPDGDKTV VQPDILILEG LNVLQSGMDY PHDPHHVFVS DFVDFSIYVD APEDLLQTWY 240
  241 INRFLKFREG AFTDPDSYFH NYAKLTKEEA IKTAMTLWKE INWLNLKQNI LPTRERASLI 300
  301 LTKSANHAVE EVRLRK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.69897
Match:	1esmA
Description:	Pantothenate kinase PanK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.37148167194523	bayes_pls_golite062009
dephospho-CoA kinase activity	0.747335572592521	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: