YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213427839
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E02-1180
Length:	375 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213427839.

Description	E-value	Query Range	Subject Range
TGT_SALPA - Queuine tRNA-ribosyltransferase OS=Salmonella paratyphi A GN=tgt PE=3 SV=1 TGT_SALPA - Queuine tRNA-ribosyltransferase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=tgt PE=3 SV... TGT_SALPK - Queuine tRNA-ribosyltransferase OS=Salmonella paratyphi A (strain AKU_12601) GN=tgt PE=3 SV=1	0.0	[1..375]	[1..375]
TGT_ECOLI - Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (tRNA-guanine transglycosylase) (Guanine insertion enz... EG10996 - tRNA-guanine transglycosylase / tRNA-guanine transglycosylase; queuosine biosynthesis; zinc metallop... sp\|B7UJM9\|TGT_ECO27 - Queuine tRNA-ribosyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=tgt PE=3 SV=... TGT_ECO57 - Queuine tRNA-ribosyltransferase OS=Escherichia coli O157:H7 GN=tgt PE=3 SV=1 gi\|168761606, gi... - gi\|189368083\|gb\|EDU86499.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC4501], ... EG10996 - tRNA-guanine transglycosylase / tRNA-guanine transglycosylase; queuosine biosynthesis; zinc metallop... gi\|168756942, gi... - gi\|189355997\|gb\|EDU74416.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC4401], ... gi\|15800133, gi\|... - gi\|15800133\|ref\|NP_286145.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 EDL933], gi\|1... gi\|187768312, gi... - gi\|187768312\|gb\|EDU32156.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC4196], ... gi\|168768351, gi... - gi\|189362370\|gb\|EDU80789.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC4486], ... TGT_ECOL5 - Queuine tRNA-ribosyltransferase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=tgt PE=3 SV=1 gi\|168786247, gi... - gi\|189373558\|gb\|EDU91974.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC869], g... gi\|188999381, gi... - gi\|188999381\|gb\|EDU68367.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC4076], ... TGT_ECODH - Queuine tRNA-ribosyltransferase OS=Escherichia coli (strain K12 / DH10B) GN=tgt PE=3 SV=1 gi\|189377390, gi... - gi\|189377390\|gb\|EDU95806.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC508], g... gi\|227838672, gi... - gi\|227884586\|ref\|ZP_04002391.1\| queuine tRNA-ribosyltransferase [Escherichia coli 83972], gi\|2278386... gi\|226898810, gi... - gi\|237707600\|ref\|ZP_04538081.1\| tRNA-guanine transglycosylase [Escherichia sp. 3_2_53FAA], gi\|226898... TGT_ECOBW - Queuine tRNA-ribosyltransferase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=tgt PE=3 SV=1 gi\|242376184, gi... - gi\|251783911\|ref\|YP_002998215.1\| hypothetical protein B21_00358 [Escherichia coli BL21], gi\|24237618... gi\|253325653, gi... - gi\|254287276\|ref\|YP_003053024.1\| queuine tRNA-ribosyltransferase [Escherichia coli BL21(DE3)], gi\|25... gi\|168749862, gi... - gi\|188015892\|gb\|EDU54014.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC4113], ... gi\|253972373, gi... - gi\|254160472\|ref\|YP_003043580.1\| queuine tRNA-ribosyltransferase [Escherichia coli B str. REL606], g... gi\|254791587, gi... - gi\|254791587\|ref\|YP_003076424.1\| tRNA-guanine transglycosylase [Escherichia coli O157:H7 str. TW1435... TGT_ESCF3 - Queuine tRNA-ribosyltransferase OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-... gi\|217321349, gi... - gi\|217325128\|ref\|ZP_03441212.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. TW145... TGT_ECO45 - Queuine tRNA-ribosyltransferase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=tgt PE=3 SV=1 TGT_ECO8A - Queuine tRNA-ribosyltransferase OS=Escherichia coli O8 (strain IAI1) GN=tgt PE=3 SV=1 TGT_ECO55 - Queuine tRNA-ribosyltransferase OS=Escherichia coli (strain 55989 / EAEC) GN=tgt PE=3 SV=1 TGT_ECO81 - Queuine tRNA-ribosyltransferase OS=Escherichia coli O81 (strain ED1a) GN=tgt PE=3 SV=1 TGT_ECOL6 - Queuine tRNA-ribosyltransferase OS=Escherichia coli O6 GN=tgt PE=3 SV=1 TGT_ECOLU - Queuine tRNA-ribosyltransferase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=tgt PE=3 ... TGT_ECO7I - Queuine tRNA-ribosyltransferase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=tgt PE=3 SV=1 gi\|195938531 - gi\|195938531\|ref\|ZP_03083913.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC402... TGT_ECOSM - Queuine tRNA-ribosyltransferase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=tgt PE=3 SV=1 gi\|208731449, gi... - gi\|208814801\|ref\|ZP_03255980.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC404... gi\|208728485, gi... - gi\|208808684\|ref\|ZP_03251021.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC420... TGT_ECO5E - Queuine tRNA-ribosyltransferase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=tgt PE=3 SV=1 gi\|208823281, gi... - gi\|208823281\|ref\|ZP_03263599.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC404... TGT_ECO27 - Queuine tRNA-ribosyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=tgt PE=3 SV=... TGT_ECOL6 - Queuine tRNA-ribosyltransferase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=tg... TGT_ECOSE - Queuine tRNA-ribosyltransferase OS=Escherichia coli (strain SE11) GN=tgt PE=3 SV=1 gi\|85674546, gi\|... - gi\|89107276\|ref\|AP_001056.1\| tRNA-guanine transglycosylase [Escherichia coli str. K-12 substr. W3110... TGT_SHIDS - Queuine tRNA-ribosyltransferase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=tgt PE=3 SV=1 TGT_SHIBS - Queuine tRNA-ribosyltransferase OS=Shigella boydii serotype 4 (strain Sb227) GN=tgt PE=3 SV=1 gi\|191166689, gi... - gi\|75230131\|ref\|ZP_00716635.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Escherichia col... gi\|192958012, gi... - gi\|75237213\|ref\|ZP_00721260.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Escherichia col... TGT_ECOHS - Queuine tRNA-ribosyltransferase OS=Escherichia coli O9:H4 (strain HS) GN=tgt PE=3 SV=1 TGT_ECOUT - Queuine tRNA-ribosyltransferase OS=Escherichia coli (strain UTI89 / UPEC) GN=tgt PE=3 SV=1 gi\|194428845, gi... - gi\|75209962\|ref\|ZP_00710151.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Escherichia col... gi\|15829711, gi\|... - gi\|15829711\|ref\|NP_308484.1\| queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. Sakai], ... gi\|188494583, gi... - gi\|75512467\|ref\|ZP_00735006.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Escherichia col... TGT_SHISS - Queuine tRNA-ribosyltransferase OS=Shigella sonnei (strain Ss046) GN=tgt PE=3 SV=1 gi\|190906190, gi... - gi\|75238733\|ref\|ZP_00722721.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Escherichia col... gi\|75256778, gi\|... - gi\|75256778\|ref\|ZP_00728383.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Escherichia col... TGT_SHIB3 - Queuine tRNA-ribosyltransferase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=tgt P... TGT_ECO24 - Queuine tRNA-ribosyltransferase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=tgt PE=3 SV=... TGT_ECOK1 - Queuine tRNA-ribosyltransferase OS=Escherichia coli O1:K1 / APEC GN=tgt PE=3 SV=1 gi\|83570326, gi\|... - gi\|83570326\|ref\|ZP_00921771.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Shigella dysent... gi\|124500220, gi... - gi\|124528883\|ref\|ZP_01700068.1\| queuine tRNA-ribosyltransferase [Escherichia coli B], gi\|124500220\|g... gi\|83585675, gi\|... - gi\|83585675\|ref\|ZP_00924317.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Escherichia col... TGT_ECOLC - Queuine tRNA-ribosyltransferase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=tgt PE...	0.0	[1..375]	[1..375]
gi\|89072680, gi\|... - gi\|89072680\|ref\|ZP_01159245.1\| queuine tRNA-ribosyltransferase [Photobacterium sp. SKA34], gi\|890515...	0.0	[1..373]	[1..373]
gi\|116190745, gi... - gi\|75832015\|ref\|ZP_00761274.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Vibrio cholerae... gi\|150421374, gi... - gi\|75823250\|ref\|ZP_00752766.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Vibrio cholerae... gi\|125622393, gi... - gi\|75818786\|ref\|ZP_00748910.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Vibrio cholerae... TGT_VIBCM - Queuine tRNA-ribosyltransferase OS=Vibrio cholerae serotype O1 (strain M66-2) GN=tgt PE=3 SV=1 gi\|229357868, gi... - gi\|229505645\|ref\|ZP_04395155.1\| tRNA-guanine transglycosylase [Vibrio cholerae BX 330286], gi\|229357... gi\|153829390, gi... - gi\|153829390\|ref\|ZP_01982057.1\| queuine tRNA-ribosyltransferase [Vibrio cholerae 623-39], gi\|1488751... gi\|229513120, gi... - gi\|229513120\|ref\|ZP_04402586.1\| tRNA-guanine transglycosylase [Vibrio cholerae TMA 21], gi\|229350013... gi\|229517805, gi... - gi\|229517805\|ref\|ZP_04407249.1\| tRNA-guanine transglycosylase [Vibrio cholerae RC9], gi\|229344520\|gb... TGT_VIBCH - Queuine tRNA-ribosyltransferase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16... gi\|229339799, gi... - gi\|229523436\|ref\|ZP_04412843.1\| tRNA-guanine transglycosylase [Vibrio cholerae TM 11079-80], gi\|2293... gi\|229525387, gi... - gi\|229525387\|ref\|ZP_04414792.1\| tRNA-guanine transglycosylase [Vibrio cholerae bv. albensis VL426], ... gi\|229333903, gi... - gi\|229530129\|ref\|ZP_04419519.1\| tRNA-guanine transglycosylase [Vibrio cholerae 12129(1)], gi\|2293339... gi\|229371318, gi... - gi\|229608663\|ref\|YP_002879311.1\| tRNA-guanine transglycosylase [Vibrio cholerae MJ-1236], gi\|2293713... gi\|124113666, gi... - gi\|153217325\|ref\|ZP_01951076.1\| queuine tRNA-ribosyltransferase [Vibrio cholerae 1587], gi\|124113666... gi\|153220705, gi... - gi\|153220705\|ref\|ZP_01951816.1\| queuine tRNA-ribosyltransferase [Vibrio cholerae MAK 757], gi\|124120... gi\|153802817, gi... - gi\|153802817\|ref\|ZP_01957403.1\| queuine tRNA-ribosyltransferase [Vibrio cholerae MZO-3], gi\|12412164... gi\|153818846, gi... - gi\|153818846\|ref\|ZP_01971513.1\| queuine tRNA-ribosyltransferase [Vibrio cholerae NCTC 8457], gi\|1265... gi\|254285459, gi... - gi\|254285459\|ref\|ZP_04960423.1\| queuine tRNA-ribosyltransferase [Vibrio cholerae AM-19226], gi\|19775... TGT_VIBCH - Queuine tRNA-ribosyltransferase OS=Vibrio cholerae GN=tgt PE=3 SV=1 gi\|229510683, gi... - gi\|229510683\|ref\|ZP_04400162.1\| tRNA-guanine transglycosylase [Vibrio cholerae B33], gi\|229350648\|gb...	0.0	[1..375]	[3..377]
gi\|90579386, gi\|... - gi\|90579386\|ref\|ZP_01235196.1\| queuine tRNA-ribosyltransferase [Vibrio angustum S14], gi\|90440219\|gb...	0.0	[1..373]	[1..373]
TGT_SHIFL - Queuine tRNA-ribosyltransferase OS=Shigella flexneri GN=tgt PE=3 SV=1 gi\|24111784, gi\|... - gi\|24111784\|ref\|NP_706294.1\| queuine tRNA-ribosyltransferase [Shigella flexneri 2a str. 301], gi\|240... gi\|30040145, gi\|... - gi\|30061901\|ref\|NP_836072.1\| queuine tRNA-ribosyltransferase [Shigella flexneri 2a str. 2457T], gi\|3... TGT_SHIF8 - Queuine tRNA-ribosyltransferase OS=Shigella flexneri serotype 5b (strain 8401) GN=tgt PE=3 SV=1	0.0	[1..375]	[1..375]
TGT_PHOLL - Queuine tRNA-ribosyltransferase OS=Photorhabdus luminescens subsp. laumondii GN=tgt PE=3 SV=1 TGT_PHOLL - Queuine tRNA-ribosyltransferase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP...	0.0	[1..374]	[1..374]
gi\|205329470, gi... - gi\|205329470\|gb\|EDZ16234.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... TGT_SALTY - Queuine tRNA-ribosyltransferase OS=Salmonella typhimurium GN=tgt PE=3 SV=1 gi\|205333452, gi... - gi\|205333452\|gb\|EDZ20216.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... TGT_SALPB - Queuine tRNA-ribosyltransferase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=tgt PE=3 ... gi\|197289492, gi... - gi\|197289492\|gb\|EDY28855.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... TGT_SALTY - Queuine tRNA-ribosyltransferase OS=Salmonella typhimurium GN=tgt PE=3 SV=1 lcl\|NC_016856.1_... - [gene=tgt] [protein=queuine tRNA-ribosyltransferase] [protein_id=YP_005236096.1] [location=461514..4... TGT_SALTY - Queuine tRNA-ribosyltransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=t... gi\|238911461 - gi\|238911461\|ref\|ZP_04655298.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... TGT_SALA4 - Queuine tRNA-ribosyltransferase OS=Salmonella agona (strain SL483) GN=tgt PE=3 SV=1 gi\|197242718, gi... - gi\|197264463\|ref\|ZP_03164537.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... gi\|200390123, gi... - gi\|200390123\|ref\|ZP_03216734.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... gi\|204926711, gi... - gi\|204926711\|ref\|ZP_03217913.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... TGT_SALNS - Queuine tRNA-ribosyltransferase OS=Salmonella newport (strain SL254) GN=tgt PE=3 SV=1 TGT_SALHS - Queuine tRNA-ribosyltransferase OS=Salmonella heidelberg (strain SL476) GN=tgt PE=3 SV=1 gi\|194457563, gi... - gi\|194471199\|ref\|ZP_03077183.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... TGT_SALSV - Queuine tRNA-ribosyltransferase OS=Salmonella schwarzengrund (strain CVM19633) GN=tgt PE=3 SV=1 gi\|168240225, gi... - gi\|205340287\|gb\|EDZ27051.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... TGT_SALPB - Queuine tRNA-ribosyltransferase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=tgt PE=3 ... gi\|168261165, gi... - gi\|205349783\|gb\|EDZ36414.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|195631915, gi... - gi\|195631915\|gb\|EDX50435.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|205344228, gi... - gi\|205344228\|gb\|EDZ30992.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser...	0.0	[1..375]	[1..375]
gi\|37197672, gi\|... - gi\|37678930\|ref\|NP_933539.1\| queuine tRNA-ribosyltransferase [Vibrio vulnificus YJ016], gi\|37197672\|...	0.0	[1..372]	[58..429]
gi\|147966 - gi\|147966\|gb\|AAA24667.1\| transfer RNA-guanine transglycosylase	0.0	[1..375]	[1..375]

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Predicted Domain #1

Region A:
Residues: [1-375]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFELDTTDG RARRGRLVFD RGVVETPAFM PVGTYGTVKG MTPEEVEATG AQIILGNTFH  60
   61 LWLRPGQEIM KLHGDLHDFM QWKGPILTDS GGFQVFSLGD IRKITEQGVH FRNPINGDPI 120
  121 FLDPEKSMEI QYDLGSDIVM IFDECTPYPA DWDYAKRSME MSLRWAKRSR DRFDSLGNKN 180
  181 ALFGIIQGSV YEDLRDISVK GLVEIGFDGY AVGGLAVGEP KADMHRILEH VCPQIPADKP 240
  241 RYLMGVGKPE DLVEGVRRGI DMFDCVMPTR NARNGHLFVT DGVVKIRNAK HKSDISPLDA 300
  301 ECDCYTCRNY SRAYLHHLDR CNEILGARLN TIHNLRYYQR LMAGLRKAIE EGKLESFVTE 360
  361 FYQRQGRPVP PLNVD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	158.0
Match:	1ozmA
Description:	Y106F mutant of Z. mobilis TGT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
queuine tRNA-ribosyltransferase activity	5.68673071384353	bayes_pls_golite062009
transferase activity	3.21194535271238	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.84864811414771	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.53039738178366	bayes_pls_golite062009
catalytic activity	2.02168745464921	bayes_pls_golite062009
binding	1.29132603807317	bayes_pls_golite062009
protein binding	0.136438951368546	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: