YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213610138
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E98-2068
Length:	287 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213610138.

Description	E-value	Query Range	Subject Range
lcl\|NC_016856.1_... - [gene=tsx] [protein=nucleoside channel] [protein_id=YP_005236104.1] [location=complement(468230..469... gi\|62179024, gi\|... - gi\|62179024\|ref\|YP_215441.1\| nucleoside channel; receptor of phage T6 and colicin K [Salmonella ente...	2.0E-90	[1..287]	[36..322]
gi\|152968936, gi... - gi\|152968936\|ref\|YP_001334045.1\| nucleoside channel; receptor of phage T6 and colicin K [Klebsiella ... TSX_KLEPN - Nucleoside-specific channel-forming protein tsx OS=Klebsiella pneumoniae GN=tsx PE=3 SV=1	2.0E-89	[1..287]	[1..294]
gi\|56414432, gi\|... - gi\|56414432\|ref\|YP_151507.1\| nucleoside-specific channel-forming protein tsx precursor [Salmonella e... gi\|197363352, gi... - gi\|197363352\|ref\|YP_002142989.1\| nucleoside-specific channel-forming protein tsx precursor [Salmonel...	2.0E-88	[1..287]	[1..287]
gi\|237707595, gi... - gi\|237707595\|ref\|ZP_04538076.1\| nucleoside-specific channel-forming protein tsx [Escherichia sp. 3_2... gi\|91071053, gi\|... - gi\|91209479\|ref\|YP_539465.1\| nucleoside channel; receptor of phage T6 and colicin K [Escherichia col... gi\|26106814, gi\|... - gi\|26246416\|ref\|NP_752455.1\| nucleoside-specific channel-forming protein tsx precursor [Escherichia ...	1.0E-83	[1..287]	[17..310]
gi\|15800140, gi\|... - gi\|15800140\|ref\|NP_286152.1\| nucleoside channel; receptor of phage T6 and colicin K [Escherichia col... gi\|25348404 - gi\|25348404\|pir\|\|D85537 hypothetical protein tsx [imported] - Escherichia coli (strain O157:H7, sub...	2.0E-83	[1..287]	[1..294]
gi\|89107281, gi\|... - gi\|89107281\|ref\|AP_001061.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia col... gi\|56383200, gi\|... - gi\|56479649\|ref\|NP_706299.2\| outer membrane protein Tsx [Shigella flexneri 2a str. 301], gi\|56383200... gi\|188487522, gi... - gi\|75512472\|ref\|ZP_00735011.1\| COG3248: Nucleoside-binding outer membrane protein [Escherichia coli ... TSX_SHIFL - Nucleoside-specific channel-forming protein tsx OS=Shigella flexneri GN=tsx PE=3 SV=1 gi\|81239832, gi\|... - gi\|82775684\|ref\|YP_402031.1\| nucleoside channel [Shigella dysenteriae Sd197], gi\|81239832\|gb\|ABB6054... gi\|30061906, gi\|... - gi\|30061906\|ref\|NP_836077.1\| outer membrane protein Tsx [Shigella flexneri 2a str. 2457T], gi\|300401... TSX_ECO57 - Nucleoside-specific channel-forming protein tsx OS=Escherichia coli O157:H7 GN=tsx PE=3 SV=1 EG11035 - nucleoside channel, receptor of phage T6 and colicin K / Outer membrane channel for nucleosides; rec... gi\|75189478, gi\|... - gi\|75189478\|ref\|ZP_00702745.1\| COG3248: Nucleoside-binding outer membrane protein [Escherichia coli ... TSX_ECOLI - Nucleoside-specific channel-forming protein tsx precursor - Escherichia coli gi\|75194630, gi\|... - gi\|75194630\|ref\|ZP_00704700.1\| COG3248: Nucleoside-binding outer membrane protein [Escherichia coli ... gi\|83585670, gi\|... - gi\|83585670\|ref\|ZP_00924312.1\| COG3248: Nucleoside-binding outer membrane protein [Escherichia coli ... gi\|75237208, gi\|... - gi\|75237208\|ref\|ZP_00721255.1\| COG3248: Nucleoside-binding outer membrane protein [Escherichia coli ... gi\|188015880, gi... - gi\|188015880\|gb\|EDU54002.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O157:H... gi\|193065192, gi... - gi\|75256783\|ref\|ZP_00728388.1\| COG3248: Nucleoside-binding outer membrane protein [Escherichia coli ... gi\|75209967, gi\|... - gi\|75209967\|ref\|ZP_00710156.1\| COG3248: Nucleoside-binding outer membrane protein [Escherichia coli ... gi\|189368014, gi... - gi\|189368014\|gb\|EDU86430.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O157:H... gi\|75230136, gi\|... - gi\|75230136\|ref\|ZP_00716640.1\| COG3248: Nucleoside-binding outer membrane protein [Escherichia coli ... gi\|189355995, gi... - gi\|189355995\|gb\|EDU74414.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O157:H... gi\|208806647, gi... - gi\|208806647\|ref\|ZP_03248984.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O1... gi\|13359921, gi\|... - gi\|15829718\|ref\|NP_308491.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O157:... gi\|195938524 - gi\|195938524\|ref\|ZP_03083906.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia ... gi\|110613981, gi... - gi\|110804433\|ref\|YP_687953.1\| outer membrane protein Tsx [Shigella flexneri 5 str. 8401], gi\|1106139... gi\|208823093, gi... - gi\|208823093\|ref\|ZP_03263411.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O1... gi\|208815572, gi... - gi\|208815572\|ref\|ZP_03256751.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O1... gi\|209917624, gi... - gi\|209917624\|ref\|YP_002291708.1\| nucleoside channel protein [Escherichia coli SE11], gi\|209910883\|db... gi\|209398558, gi... - gi\|209398558\|ref\|YP_002269055.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O... gi\|217326235, gi... - gi\|217326235\|ref\|ZP_03442319.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O1... gi\|215485492, gi... - gi\|215485492\|ref\|YP_002327923.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia... gi\|187768263, gi... - gi\|187768263\|gb\|EDU32107.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O157:H... gi\|189362419, gi... - gi\|189362419\|gb\|EDU80838.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O157:H... gi\|189373689, gi... - gi\|189373689\|gb\|EDU92105.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O157:H... gi\|124500215, gi... - gi\|124528878\|ref\|ZP_01700063.1\| nucleoside-specific channel-forming protein, Tsx [Escherichia coli B... gi\|168783274, gi... - gi\|188999376\|gb\|EDU68362.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O157:H... gi\|169756145, gi... - gi\|170021217\|ref\|YP_001726171.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli A... gi\|168800291, gi... - gi\|189377436\|gb\|EDU95852.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli O157:H... gi\|170680575, gi... - gi\|170680575\|ref\|YP_001742548.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli S... gi\|169887832, gi... - gi\|170079997\|ref\|YP_001729317.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia... EG11035 - nucleoside channel, receptor of phage T6 and colicin K / Outer membrane channel for nucleosides; rec... gi\|218693872, gi... - gi\|218693872\|ref\|YP_002401539.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia... gi\|238899699, gi... - gi\|238899699\|ref\|YP_002925495.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia... gi\|218552974, gi... - gi\|218552974\|ref\|YP_002385887.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia... gi\|242376189, gi... - gi\|251783916\|ref\|YP_002998220.1\| hypothetical protein B21_00363 [Escherichia coli BL21], gi\|24237618... gi\|218703693, gi... - gi\|218703693\|ref\|YP_002411212.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia... gi\|253774604, gi... - gi\|254287281\|ref\|YP_003053029.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia... gi\|218368668, gi... - gi\|218698682\|ref\|YP_002406311.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia... gi\|254791594, gi... - gi\|254791594\|ref\|YP_003076431.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia...	2.0E-83	[1..287]	[1..294]
gi\|194419115, gi... - gi\|83570321\|ref\|ZP_00921766.1\| COG3248: Nucleoside-binding outer membrane protein [Shigella dysenter...	2.0E-83	[1..287]	[1..294]
gi\|191173474, gi... - gi\|75238738\|ref\|ZP_00722726.1\| COG3248: Nucleoside-binding outer membrane protein [Escherichia coli ... gi\|110640672, gi... - gi\|110640672\|ref\|YP_668400.1\| nucleoside-specific channel-forming protein tsx precursor [Escherichia... gi\|227884581, gi... - gi\|227884581\|ref\|ZP_04002386.1\| nucleoside-specific channel-forming protein tsx precursor [Escherich... gi\|117622672, gi... - gi\|117622672\|ref\|YP_851585.1\| nucleoside-specific channel-forming protein Tsx [Escherichia coli APEC... gi\|218364089, gi... - gi\|218557320\|ref\|YP_002390233.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia... gi\|218425838, gi... - gi\|218688274\|ref\|YP_002396486.1\| nucleoside channel, receptor of phage T6 and colicin K [Escherichia...	6.0E-83	[1..287]	[1..294]
gi\|74310980, gi\|... - gi\|74310980\|ref\|YP_309399.1\| nucleoside channel [Shigella sonnei Ss046], gi\|73854457\|gb\|AAZ87164.1\| ...	7.0E-83	[1..287]	[1..294]
gi\|187733170, gi... - gi\|75176885\|ref\|ZP_00697001.1\| COG3248: Nucleoside-binding outer membrane protein [Shigella boydii B... gi\|81244310, gi\|... - gi\|82542899\|ref\|YP_406846.1\| Tsx [Shigella boydii Sb227], gi\|81244310\|gb\|ABB65018.1\| Tsx [Shigella b...	1.0E-82	[1..287]	[1..294]

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Predicted Domain #1

Region A:
Residues: [1-287]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKTLLAVSA ALALTSSFTA NAAENDQPQY LSDWWHQSVN VVGSYHTRFS PKLNNDVYLE  60
   61 YEAFAKKDWF DFYGYIDIPK TFDWGNGNDK GIWSDGSPLF MEIEPRFSID KLTGADLSFG 120
  121 PFKEWYFANN YIYDMGDNKA SRQSTWYMGL GTDIDTGLPM GLSLNVYAKY QWQNYGASNE 180
  181 NEWDGYRFKV KYFVPITDLW GGKLSYIGFT NFDWGSDLGD DPNRTSNSIA SSHILALNYD 240
  241 HWHYSVVARY FHNGGQWQNG AKLNWGDGDF SAKSTGWGGY LVVGYNF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.045757
Match:	1tlwA
Description:	Tsx structure complexed with thymidine
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleoside transmembrane transporter activity	10.4297934011355	bayes_pls_golite062009
nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity	5.73088734190731	bayes_pls_golite062009
transporter activity	2.55928656852707	bayes_pls_golite062009
transmembrane transporter activity	2.44072409024655	bayes_pls_golite062009
substrate-specific transporter activity	2.14215782778459	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.06465400776497	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: