YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213650024
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. J185
Length:	243 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213650024.

Description	E-value	Query Range	Subject Range
EG12008 - transcriptional activator of csgD and csgBA / Transcriptional regulator of csgD gi\|15146422\|gb\|A... - MerR-like regulator A [Escherichia coli] EG12008 - transcriptional activator of csgD and csgBA / Transcriptional regulator of csgD gi\|124526704, gi... - gi\|124526704\|ref\|ZP_01698613.1\| transcriptional regulator, MerR family [Escherichia coli B], gi\|1245... gi\|218554691, gi... - gi\|218554691\|ref\|YP_002387604.1\| DNA-binding transcriptional regulator [Escherichia coli IAI1], gi\|2... gi\|218695738, gi... - gi\|218695738\|ref\|YP_002403405.1\| DNA-binding transcriptional regulator [Escherichia coli 55989], gi\|... gi\|157080228, gi... - gi\|75186917\|ref\|ZP_00700184.1\| COG0789: Predicted transcriptional regulators [Escherichia coli E2437... gi\|226237481 - gi\|226237481\|dbj\|BAH47003.1\| DNA-binding transcriptional regulator [Escherichia coli O55:H7] gi\|238901310, gi... - gi\|238901310\|ref\|YP_002927106.1\| DNA-binding transcriptional regulator [Escherichia coli BW2952], gi... gi\|89108943, gi\|... - gi\|89108943\|ref\|AP_002723.1\| DNA-binding transcriptional regulator [Escherichia coli str. K-12 subst... gi\|75231533, gi\|... - gi\|75231533\|ref\|ZP_00717902.1\| COG0789: Predicted transcriptional regulators [Escherichia coli B7A],... gi\|169754483, gi... - gi\|170019555\|ref\|YP_001724509.1\| MerR family transcriptional regulator [Escherichia coli ATCC 8739],... gi\|170081749, gi... - gi\|170081749\|ref\|YP_001731069.1\| DNA-binding transcriptional regulator [Escherichia coli str. K-12 s... MLRA_ECOLI - HTH-type transcriptional regulator mlrA (MerR-like regulator A) - Escherichia coli gi\|209912845, gi... - gi\|209919586\|ref\|YP_002293670.1\| putative transcriptional regulator [Escherichia coli SE11], gi\|2099...	2.0E-60	[1..243]	[1..243]
gi\|253974042, gi... - gi\|254162141\|ref\|YP_003045249.1\| DNA-binding transcriptional regulator [Escherichia coli B str. REL6... gi\|253323990, gi... - gi\|254288903\|ref\|YP_003054651.1\| DNA-binding transcriptional regulator [Escherichia coli BL21(DE3)],... gi\|194436166, gi... - gi\|83588109\|ref\|ZP_00926734.1\| COG0789: Predicted transcriptional regulators [Escherichia coli 101-1... gi\|242377768, gi... - gi\|251785495\|ref\|YP_002999799.1\| hypothetical protein B21_02014 [Escherichia coli BL21], gi\|24237776...	3.0E-60	[1..243]	[1..243]
gi\|190909645, gi... - gi\|75242944\|ref\|ZP_00726650.1\| COG0789: Predicted transcriptional regulators [Escherichia coli F11],... gi\|110343927, gi... - gi\|110642335\|ref\|YP_670065.1\| MerR-like regulator A [Escherichia coli 536], gi\|110343927\|gb\|ABG70164...	4.0E-60	[1..243]	[1..243]
gi\|82777390, gi\|... - gi\|82777390\|ref\|YP_403739.1\| putative transcriptional regulator [Shigella dysenteriae Sd197], gi\|812...	7.0E-60	[1..243]	[1..243]
gi\|117624330, gi... - gi\|117624330\|ref\|YP_853243.1\| MerR-like regulator A [Escherichia coli APEC O1], gi\|115513454\|gb\|ABJ0... gi\|237704587, gi... - gi\|237704587\|ref\|ZP_04535068.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|91072986, gi\|... - gi\|91211412\|ref\|YP_541398.1\| putative transcriptional regulator [Escherichia coli UTI89], gi\|9107298... gi\|218559045, gi... - gi\|218559045\|ref\|YP_002391958.1\| DNA-binding transcriptional regulator [Escherichia coli S88], gi\|21...	7.0E-60	[1..243]	[1..243]
gi\|26108910, gi\|... - gi\|26248505\|ref\|NP_754545.1\| MerR-like regulator A [Escherichia coli CFT073], gi\|26108910\|gb\|AAN8111... gi\|227887181, gi... - gi\|227887181\|ref\|ZP_04004986.1\| MerR family regulator A [Escherichia coli 83972], gi\|227835531\|gb\|EE...	3.0E-59	[1..243]	[1..243]
gi\|194456184, gi... - gi\|194469820\|ref\|ZP_03075804.1\| transcriptional regulator, MerR family protein [Salmonella enterica ... gi\|168818134, gi... - gi\|205344751\|gb\|EDZ31515.1\| transcriptional regulator, MerR family protein [Salmonella enterica subs... gi\|195631163, gi... - gi\|195631163\|gb\|EDX49723.1\| transcriptional regulator, MerR family protein [Salmonella enterica subs... gi\|205350932, gi... - gi\|205350932\|gb\|EDZ37563.1\| transcriptional regulator, MerR family protein [Salmonella enterica subs... gi\|197361857, gi... - gi\|197361857\|ref\|YP_002141493.1\| putative transcriptional regulator [Salmonella enterica subsp. ente... gi\|197264719, gi... - gi\|197264719\|ref\|ZP_03164793.1\| transcriptional regulator, MerR family protein [Salmonella enterica ... gi\|197251805, gi... - gi\|197251805\|ref\|YP_002147132.1\| transcriptional regulator, MerR family protein [Salmonella enterica... gi\|194738337, gi... - gi\|194738337\|ref\|YP_002115250.1\| transcriptional regulator, MerR family protein [Salmonella enterica... gi\|161362516, gi... - gi\|161613152\|ref\|YP_001587117.1\| hypothetical protein SPAB_00860 [Salmonella enterica subsp. enteric... MLRA_SALTY - HTH-type transcriptional regulator mlrA OS=Salmonella typhimurium GN=mlrA PE=3 SV=1 gi\|56412926, gi\|... - gi\|56412926\|ref\|YP_150001.1\| putative transcriptional regulator [Salmonella enterica subsp. enterica... gi\|168236326, gi... - gi\|197290545\|gb\|EDY29900.1\| transcriptional regulator, MerR family protein [Salmonella enterica subs... gi\|205335583, gi... - gi\|205335583\|gb\|EDZ22347.1\| transcriptional regulator, MerR family protein [Salmonella enterica subs... gi\|205330457, gi... - gi\|205330457\|gb\|EDZ17221.1\| transcriptional regulator, MerR family protein [Salmonella enterica subs... gi\|167551113, gi... - gi\|205324022\|gb\|EDZ11861.1\| transcriptional regulator, MerR family protein [Salmonella enterica subs... MLRA_SALTY - HTH-type transcriptional regulator mlrA OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 7007... lcl\|NC_016856.1_... - [gene=yehV] [protein=putative transcriptional repressor] [protein_id=YP_005238203.1] [location=23079... gi\|238912603 - gi\|238912603\|ref\|ZP_04656440.1\| putative transcriptional regulator [Salmonella enterica subsp. enter... MLRA_SALTS - HTH-type transcriptional regulator mlrA OS=Salmonella typhimurium (strain SL1344) GN=mlrA PE=3 SV=1 gi\|224583338, gi... - gi\|224583338\|ref\|YP_002637136.1\| putative transcriptional regulator [Salmonella enterica subsp. ente... gi\|204321845, gi... - gi\|204929301\|ref\|ZP_03220444.1\| transcriptional regulator, MerR family protein [Salmonella enterica ... MLRA_SALTY - HTH-type transcriptional regulator mlrA OS=Salmonella typhimurium GN=mlrA PE=4 SV=1 gi\|199605929, gi... - gi\|200388831\|ref\|ZP_03215443.1\| transcriptional regulator, MerR family protein [Salmonella enterica ...	3.0E-55	[1..243]	[1..243]
gi\|62128379, gi\|... - gi\|62180746\|ref\|YP_217163.1\| MerR family transcriptional regulator [Salmonella enterica subsp. enter...	1.0E-54	[1..243]	[1..243]
gi\|188487610, gi... - gi\|75511654\|ref\|ZP_00734301.1\| COG0789: Predicted transcriptional regulators [Escherichia coli 53638...	2.0E-50	[1..238]	[1..238]
gi\|209918396, gi... - gi\|209918396\|ref\|YP_002292480.1\| putative transcriptional regulator [Escherichia coli SE11], gi\|2099... gi\|157080691, gi... - gi\|75190223\|ref\|ZP_00703490.1\| COG0789: Predicted transcriptional regulators [Escherichia coli E2437...	2.0E-50	[1..238]	[1..238]

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Predicted Domain #1

Region A:
Residues: [1-132]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALYTIGEVA LLCDINPVTL RAWQRRYGLL KPQRTDGGHR LFNDADIDRI REIKRWIDNG  60
   61 VQVSKVKVLL SSDSSEQPNG WREQQEILLH YLQSSNLHSL RLWVKERGQD YPAQTLTTNL 120
  121 FVPLRRRLQC QQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.522879
Match:	1q05A
Description:	Crystal structure of the Cu(I) form of E. coli CueR, a copper efflux regulator
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [133-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PALQALLGIL DGILINYIAL CLASARKKQG KDALVIGWNI HDTTRLWLEG WVASQQGWRI  60
   61 DVLAHSLSQF RPELFDGKTL LVWCGEHQTL AQQQQLLAWR AQGHDIHPLG V

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.710	0.339	nucleotide binding	c.2.1	NAD(P)-binding Rossmann-fold domains
View	Download	0.786	N/A	N/A	c.25.1	Ferredoxin reductase-like, C-terminal NADP-linked domain
View	Download	0.651	N/A	N/A	c.2.1	NAD(P)-binding Rossmann-fold domains
View	Download	0.650	N/A	N/A	c.25.1	Ferredoxin reductase-like, C-terminal NADP-linked domain
View	Download	0.576	N/A	N/A	d.17.2	Copper amine oxidase, domains 1 and 2

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits