YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|219934045, gi...
Organism:	Mycobacterium leprae Br4923
Length:	458 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|219934045, gi....

Description	E-value	Query Range	Subject Range
gi\|75910833, gi\|... - gi\|75910833\|ref\|YP_325129.1\| thioredoxin reductase [Anabaena variabilis ATCC 29413], gi\|75704558\|gb\|...	262.0	[0..7]	[454..2]
gi\|53687934 - gi\|53687934\|ref\|ZP_00109021.2\| COG0492: Thioredoxin reductase [Nostoc punctiforme PCC 73102]	261.0	[0..7]	[454..4]
gi\|53762881, gi\|... - gi\|81299434\|ref\|YP_399642.1\| thioredoxin reductase [Synechococcus elongatus PCC 7942], gi\|81168315\|g...	259.0	[0..14]	[458..7]
gi\|56750910, gi\|... - gi\|56750910\|ref\|YP_171611.1\| thioredoxin reductase [Synechococcus elongatus PCC 6301], gi\|56685869\|d...	258.0	[0..14]	[458..7]
gi\|17130082, gi\|... - gi\|17228232\|ref\|NP_484780.1\| thioredoxin reductase [Nostoc sp. PCC 7120], gi\|17130082\|dbj\|BAB72694.1... gi\|25285003 - pir\|\|AG1898 thioredoxin reductase [imported] - Nostoc sp. (strain PCC 7120)	257.0	[0..7]	[454..29]
gi\|22295650, gi\|... - gi\|22299467\|ref\|NP_682714.1\| thioredoxin reductase [Thermosynechococcus elongatus BP-1], gi\|22295650...	254.0	[0..7]	[454..2]
gi\|86558772, gi\|... - gi\|86610230\|ref\|YP_478992.1\| thioredoxin-disulfide reductase [Synechococcus sp. JA-2-3B'a(2-13)], gi... gi\|86610230 - gi\|86610230\|ref\|YP_478992.1\| thioredoxin-disulfide reductase [Cyanobacteria bacterium Yellowstone B-...	254.0	[0..6]	[454..2]
gi\|115473833, gi... - gi\|34576294\|emb\|CAE46765.1\| NADPH thioredoxin reductase [Oryza sativa (japonica cultivar-group)], gi...	251.0	[0..2]	[453..32]
gi\|33865221, gi\|... - gi\|33865221\|ref\|NP_896780.1\| putative thioredoxin reductase [Synechococcus sp. WH 8102], gi\|33638905...	246.0	[0..1]	[455..1]
gi\|23308231, gi\|... - gi\|23308231\|gb\|AAN18085.1\| At2g41680/T32G6.20 [Arabidopsis thaliana], gi\|15912233\|gb\|AAL08250.1\| At2...	246.0	[0..14]	[453..86]

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Predicted Domain #1

Region A:
Residues: [1-329]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTTPSAHET IHEVIVIGSG PAGYTAALYA ARAQLTPLVF EGTSFGGALM TTTEVENYPG  60
   61 FRNGITGPEL MDDMREQALR FGAELRTEDV ESVSLRGPIK SVVTAEGQTY QARAVILAMG 120
  121 TSVRYLQIPG EQELLGRGVS ACATCDGSFF RGQDIAVIGG GDSAMEEALF LTRFARSVTL 180
  181 VHRRDEFRAS KIMLGRARNN DKIKFITNHT VVAVNGYTTV TGLRLRNTTT GEETTLVVTG 240
  241 VFVAIGHEPR SSLVSDVVDI DPDGYVLVKG RTTSTSMDGV FAAGDLVDRT YRQAITAAGS 300
  301 GCAAAIDAER WLAEHAGSKA NETTEETGD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.154902
Match:	2a87A
Description:	Crystal Structure of M. tuberculosis Thioredoxin reductase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [330-458]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDSTDTTDWS TAMTDAKNAG VTIEVTDASF FADVLSSNKP VLVDFWATWC GPCKMVAPVL  60
   61 EEIASEQRNQ LTVAKLDVDT NPEMAREFQV VSIPTMILFQ GGQPVKRIVG AKGKAALLRD 120
  121 LSDVVPNLN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.69897
Match:	2i1uA
Description:	No description for 2i1uA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits