YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213976152
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. AG3
Length:	429 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213976152.

Description	E-value	Query Range	Subject Range
RSMB_ECOL5 - Ribosomal RNA small subunit methyltransferase B OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) G...	3.0E-91	[1..429]	[1..429]
RSMB_SHISS - Ribosomal RNA small subunit methyltransferase B OS=Shigella sonnei (strain Ss046) GN=rsmB PE=3 SV=1	1.0E-90	[1..429]	[1..429]
gi\|191174468, gi... - gi\|75236340\|ref\|ZP_00720447.1\| COG0144: tRNA and rRNA cytosine-C5-methylases [Escherichia coli F11],...	1.0E-90	[1..429]	[1..429]
RSMB_SHIDS - Ribosomal RNA small subunit methyltransferase B OS=Shigella dysenteriae serotype 1 (strain Sd197) GN...	1.0E-90	[1..429]	[1..429]
gi\|237703018, gi... - gi\|237703018\|ref\|ZP_04533499.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22690... RSMB_ECO45 - Ribosomal RNA small subunit methyltransferase B OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=r... RSMB_ECOUT - Ribosomal RNA small subunit methyltransferase B OS=Escherichia coli (strain UTI89 / UPEC) GN=rsmB PE... RSMB_ECOK1 - Ribosomal RNA small subunit methyltransferase B OS=Escherichia coli O1:K1 / APEC GN=rsmB PE=3 SV=1	1.0E-90	[1..429]	[1..429]
RSMB_SALTY - Ribosomal RNA small subunit methyltransferase B OS=Salmonella typhimurium (strain LT2 / SGSC1412 / A... lcl\|NC_016856.1_... - [gene=sun] [protein=16S rRNA methyltransferase B] [protein_id=YP_005239598.1] [location=3592318..359... gi\|167995183, gi... - gi\|205327090\|gb\|EDZ13854.1\| ribosomal RNA small subunit methyltransferase B [Salmonella enterica sub... RSMB_SALTY - Ribosomal RNA small subunit methyltransferase B OS=Salmonella typhimurium GN=rsmB PE=3 SV=1 RSMB_SALTY - Ribosomal RNA small subunit methyltransferase B OS=Salmonella typhimurium GN=rsmB PE=3 SV=1	2.0E-90	[1..429]	[1..429]
RSMB_SHIBS - Ribosomal RNA small subunit methyltransferase B OS=Shigella boydii serotype 4 (strain Sb227) GN=rsmB...	2.0E-90	[1..429]	[1..429]
gi\|12517918, gi\|... - gi\|15803816\|ref\|NP_289850.1\| 16S rRNA methyltransferase B [Escherichia coli O157:H7 EDL933], gi\|1251... gi\|208812777, gi... - gi\|208812777\|ref\|ZP_03254106.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O1... gi\|209757340, gi... - pir\|\|F85993 hypothetical protein sun [imported] - Escherichia coli (strain O157:H7, substrain EDL93... gi\|208808123, gi... - gi\|208808123\|ref\|ZP_03250460.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O1... gi\|195939836 - gi\|195939836\|ref\|ZP_03085218.1\| 16S rRNA methyltransferase B [Escherichia coli O157:H7 str. EC4024] gi\|189375353, gi... - gi\|189375353\|gb\|EDU93769.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O157:H... gi\|217326360, gi... - gi\|217326360\|ref\|ZP_03442444.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O1... RSMB_ECO5E - Ribosomal RNA small subunit methyltransferase B OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) G... gi\|208820338, gi... - gi\|208820338\|ref\|ZP_03260658.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O1... RSMB_ECO57 - Ribosomal RNA small subunit methyltransferase B OS=Escherichia coli O157:H7 GN=rsmB PE=3 SV=1 gi\|189365121, gi... - gi\|189365121\|gb\|EDU83537.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O157:H... gi\|189354681, gi... - gi\|189354681\|gb\|EDU73100.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O157:H... gi\|168752263, gi... - gi\|188013841\|gb\|EDU51963.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O157:H... gi\|189373894, gi... - gi\|189373894\|gb\|EDU92310.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O157:H... gi\|188998877, gi... - gi\|188998877\|gb\|EDU67863.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O157:H... gi\|168777854, gi... - gi\|187767005\|gb\|EDU30849.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O157:H... gi\|189361764, gi... - gi\|189361764\|gb\|EDU80183.1\| ribosomal RNA small subunit methyltransferase B [Escherichia coli O157:H... gi\|254594625, gi... - gi\|254795225\|ref\|YP_003080062.1\| 16S rRNA m5C967 methyltransferase [Escherichia coli O157:H7 str. TW...	2.0E-90	[1..429]	[1..429]
gi\|15833408, gi\|... - gi\|15833408\|ref\|NP_312181.1\| 16S rRNA methyltransferase B [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|25303751 - pir\|\|B91148 RNA methyltransferase [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509... gi\|15833408, gi\|... - gi\|15833408\|ref\|NP_312181.1\| RNA methyltransferase [Escherichia coli O157:H7], gi\|13363627\|dbj\|BAB37...	2.0E-90	[1..429]	[1..429]
RSMB_ECO24 - Ribosomal RNA small subunit methyltransferase B OS=Escherichia coli O139:H28 (strain E24377A / ETEC)... RSMB_ECO8A - Ribosomal RNA small subunit methyltransferase B OS=Escherichia coli O8 (strain IAI1) GN=rsmB PE=3 SV... RSMB_ECO55 - Ribosomal RNA small subunit methyltransferase B OS=Escherichia coli (strain 55989 / EAEC) GN=rsmB PE... RSMB_ECOSE - Ribosomal RNA small subunit methyltransferase B OS=Escherichia coli (strain SE11) GN=rsmB PE=3 SV=1 gi\|192925853, gi... - gi\|75255413\|ref\|ZP_00727225.1\| COG0144: tRNA and rRNA cytosine-C5-methylases [Escherichia coli E22],... gi\|75214906, gi\|... - gi\|75214906\|ref\|ZP_00713385.1\| COG0144: tRNA and rRNA cytosine-C5-methylases [Escherichia coli E1100... gi\|194430276, gi... - gi\|75208439\|ref\|ZP_00708768.1\| COG0144: tRNA and rRNA cytosine-C5-methylases [Escherichia coli B171]...	3.0E-90	[1..429]	[1..429]

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Predicted Domain #1

Region A:
Residues: [1-429]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKQNNLRSL AAQAVELVVE QGQSLSNVLP PLQQKVADKD KALLQELCFG VLRTLSQLEW  60
   61 LINKLMSRPM TGKQRTVHYL IMVGFYQLLY TRVPPHAALA ETVEGAVSIK RPQLKGLING 120
  121 VLRQFQRQQE TLLNEFATSD ARFLHPGWLV KRLQNAYPTQ WQRIIEANNQ RPPMWLRVNR 180
  181 THHTRDGWLG LLEDAGMKGY PHPDYPDAVR LETPAPVHAL PGFAEGWVTV QDASAQGCAV 240
  241 FLAPQNGEHI LDLCAAPGGK TTHILEVAPE ADVLAVDIDE QRLSRVYDNL KRLGMKATVK 300
  301 QGDGRYPAQW CGEQQFDRIL LDAPCSATGV IRRHPDIKWL RRDRDIAELA QLQAEILDAV 360
  361 WPRLKPGGTL VYATCSVLPE ENRDQIKAFL QRTPDAALSE TGTPDQPGQQ NLPGGEEGDG 420
  421 FFYAKLIKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	91.69897
Match:	1sqfA
Description:	The crystal structure of E. coli Fmu binary complex with S-Adenosylmethionine at 2.1 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	4.15445027778357	bayes_pls_golite062009
rRNA methyltransferase activity	4.09362182773099	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.07153733729662	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
N-methyltransferase activity	3.0539218951403	bayes_pls_golite062009
protein methyltransferase activity	3.01384869242051	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
histone methyltransferase activity	1.90505369820945	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	1.83964463328968	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	1.75675289134467	bayes_pls_golite062009
DNA-methyltransferase activity	1.63765148226572	bayes_pls_golite062009
arginine N-methyltransferase activity	1.6030970825293	bayes_pls_golite062009
protein-arginine N-methyltransferase activity	1.6030970825293	bayes_pls_golite062009
transcription termination factor activity	1.58162486937564	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
tRNA methyltransferase activity	1.12859857407629	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	1.10713374933008	bayes_pls_golite062009
histone-arginine N-methyltransferase activity	1.05897361334523	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.703178429468566	bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity	0.639377525568296	bayes_pls_golite062009
O-methyltransferase activity	0.250946859465502	bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity	0.130104080746388	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	0.130042730841119	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: