YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213648172
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. J185
Length:	297 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213648172.

Description	E-value	Query Range	Subject Range
gi\|62178714, gi\|... - gi\|62178714\|ref\|YP_215131.1\| nicotinate-nucleotide pyrophosphorylase [Salmonella enterica subsp. ent... gi\|7688345\|emb\|C... - NadC protein [Salmonella typhimurium] gi\|7688345 - gi\|7688345\|emb\|CAB89834.1\| NadC protein [Salmonella typhimurium]	6.0E-97	[1..297]	[15..311]
lcl\|NC_016856.1_... - [gene=nadC] [protein=quinolinate phosphoribosyltransferase] [protein_id=YP_005235806.1] [location=co... NADC_SALTY - Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Salmonella typhimurium (strain LT2 / SGSC... gi\|224466517, gi... - gi\|224581990\|ref\|YP_002635788.1\| nicotinate-nucleotide pyrophosphorylase [Salmonella enterica subsp.... NADC_SALTY - Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Salmonella typhimurium GN=nadC PE=1 SV=3 gi\|194406281, gi... - gi\|194447977\|ref\|YP_002044115.1\| quinolinate phosphoribosyltransferase [Salmonella enterica subsp. e... gi\|197263332, gi... - gi\|197263332\|ref\|ZP_03163406.1\| nicotinate-nucleotide diphosphorylase [Salmonella enterica subsp. en... gi\|197937000, gi... - gi\|198242484\|ref\|YP_002214098.1\| nicotinate-nucleotide diphosphorylase [Salmonella enterica subsp. e... gi\|200388062, gi... - gi\|200388062\|ref\|ZP_03214674.1\| nicotinate-nucleotide diphosphorylase [Salmonella enterica subsp. en... gi\|167990020, gi... - gi\|205331315\|gb\|EDZ18079.1\| nicotinate-nucleotide diphosphorylase [Salmonella enterica subsp. enteri... gi\|205337522, gi... - gi\|205337522\|gb\|EDZ24286.1\| nicotinate-nucleotide diphosphorylase [Salmonella enterica subsp. enteri... gi\|205347469, gi... - gi\|205347469\|gb\|EDZ34100.1\| nicotinate-nucleotide diphosphorylase [Salmonella enterica subsp. enteri... gi\|194444228, gi... - gi\|194444228\|ref\|YP_002039377.1\| nicotinate-nucleotide diphosphorylase [Salmonella enterica subsp. e... NADC_SALTY - Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Salmonella typhimurium GN=nadC PE=1 SV=3 gi\|162139623 - gi\|162139623\|ref\|YP_215131.2\| quinolinate phosphoribosyltransferase [Salmonella enterica subsp. ente...	2.0E-96	[1..297]	[1..297]
gi\|1941992, gi\|1... - gi\|1941992\|pdb\|1QAP\|B Chain B, Quinolinic Acid Phosphoribosyltransferase With Bound Quinolinic Acid,... gi\|1941991\|pdb\|1... - Chain A, Quinolinic Acid Phosphoribosyltransferase With Bound Quinolinic Acid, Chain B, Quinolinic A...	1.0E-95	[2..297]	[1..296]
gi\|238911203 - gi\|238911203\|ref\|ZP_04655040.1\| quinolinate phosphoribosyltransferase [Salmonella enterica subsp. en... gi\|56126676, gi\|... - gi\|56412419\|ref\|YP_149494.1\| quinolinate phosphoribosyltransferase [Salmonella enterica subsp. enter... gi\|194458766, gi... - gi\|194472402\|ref\|ZP_03078386.1\| nicotinate-nucleotide diphosphorylase [Salmonella enterica subsp. en... gi\|168230426, gi... - gi\|205334949\|gb\|EDZ21713.1\| nicotinate-nucleotide diphosphorylase [Salmonella enterica subsp. enteri...	3.0E-95	[1..296]	[1..296]
gi\|37199711, gi\|... - gi\|37680961\|ref\|NP_935570.1\| quinolinate phosphoribosyltransferase [Vibrio vulnificus YJ016], gi\|371...	1.0E-93	[6..296]	[17..306]
gi\|16930777 - gi\|16930777\|gb\|AAL32048.1\|AF439854_1 NadC [Vibrio vulnificus]	2.0E-93	[6..296]	[5..294]
gi\|27361137, gi\|... - gi\|27364991\|ref\|NP_760519.1\| quinolinate phosphoribosyltransferase [Vibrio vulnificus CMCP6], gi\|273...	7.0E-93	[6..296]	[5..294]
gi\|91228624, gi\|... - gi\|91228624\|ref\|ZP_01262541.1\| nicotinate-nucleotide pyrophosphorylase [Vibrio alginolyticus 12G01],...	2.0E-92	[6..296]	[5..294]
gi\|28899296, gi\|... - gi\|28899296\|ref\|NP_798901.1\| quinolinate phosphoribosyltransferase [Vibrio parahaemolyticus RIMD 221... gi\|28807520 - gi\|28807520\|dbj\|BAC60785.1\| NadC [Vibrio parahaemolyticus RIMD 2210633]	1.0E-91	[6..296]	[5..294]
gi\|36786936, gi\|... - gi\|37527501\|ref\|NP_930845.1\| quinolinate phosphoribosyltransferase [Photorhabdus luminescens subsp. ...	6.0E-91	[1..296]	[1..295]

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Predicted Domain #1

Region A:
Residues: [1-297]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPRRYNPDD RRDALLERIN LDIPAAVAQA LREDLGGEVD AGNDITAQLL PADTQAHATV  60
   61 ITREDGVFCG KRWVEEVFIQ LAGDDVRLTW HVDDGDAIHA NQTVFELNGP ARVLLTGERT 120
  121 ALNFVQTLSG VASEVRRYVG LLAGTQTQLL DTRKTLPGLR TALKYAVLCG GGANHRLGLT 180
  181 DAFLIKENHI IASGSVRQAV EKAFWLHPDV PVEVEVENLD ELDDALKAGA DIIMLDNFNT 240
  241 DQMREAVKHV NGQARLEVSG NVTAETLREF AETGVDFISV GALTKHVRAL DLSMRFC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	97.221849
Match:	1qapA
Description:	Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain; Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinate phosphoribosyltransferase activity	3.4096751090496	bayes_pls_golite062009
nicotinate-nucleotide diphosphorylase (carboxylating) activity	3.12788282156037	bayes_pls_golite062009
binding	1.58263447797054	bayes_pls_golite062009
catalytic activity	0.60409960326459	bayes_pls_golite062009
protein binding	0.502035039039958	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: