YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|207342854
Organism:	Saccharomyces cerevisiae AWRI1631
Length:	448 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|207342854.

Description	E-value	Query Range	Subject Range
gi\|151941004 - gi\|151941004\|gb\|EDN59385.1\| exo-1,3-beta-glucanase [Saccharomyces cerevisiae YJM789] gi\|207342854 - gi\|207342854\|gb\|EDZ70488.1\| YLR300Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190405356 - gi\|190405356\|gb\|EDV08623.1\| exo-1,3-beta-glucanase [Saccharomyces cerevisiae RM11-1a] EXG1 - Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as... EXG1_YEAST - Glucan 1,3-beta-glucosidase I/II OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EXG1 PE...	0.0	[1..448]	[1..448]
EXG_KLULA - Glucan 1,3-beta-glucosidase OS=Kluyveromyces lactis GN=KLLA0C05324g PE=3 SV=1 EXG_KLULA - Glucan 1,3-beta-glucosidase OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC ...	2.0E-99	[1..445]	[1..427]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-97	[1..444]	[1..436]
EXG_CANAL - Glucan 1,3-beta-glucosidase OS=Candida albicans GN=XOG1 PE=1 SV=3	4.0E-97	[1..444]	[1..436]
EXG2_WICAO - Glucan 1,3-beta-glucosidase 2 OS=Wickerhamomyces anomalus GN=EXG2 PE=3 SV=1	7.0E-93	[1..443]	[1..426]
EXG_SCHOC - Glucan 1,3-beta-glucosidase OS=Schwanniomyces occidentalis PE=3 SV=1	3.0E-92	[6..444]	[4..424]

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Predicted Domain #1

Region A:
Residues: [1-296]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSLKTLLCT LLTVSSVLAT PVPARDPSSI QFVHEENKKR YYDYDHGSLG EPIRGVNIGG  60
   61 WLLLEPYITP SLFEAFRTND DNDEGIPVDE YHFCQYLGKD LAKSRLQSHW STFYQEQDFA 120
  121 NIASQGFNLV RIPIGYWAFQ TLDDDPYVSG LQESYLDQAI GWARNNSLKV WVDLHGAAGS 180
  181 QNGFDNSGLR DSYKFLEDSN LAVTTNVLNY ILKKYSAEEY LDTVIGIELI NEPLGPVLDM 240
  241 DKMKNDYLAP AYEYLRNNIK SDQVIIIHDA FQPYNYWDDF MTENDGYWGV TIDHHH

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [319-335]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WGTGVLNESH WTVCGEF

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [399-413]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AFEMRGGWII WCYKT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1454.0
Match:	1cz1A_
Description:	Exo-beta-(1,3)-glucanase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity, acting on glycosyl bonds	5.36248919165223	bayes_pls_golite062009
glucan 1,3-beta-glucosidase activity	5.16200085143699	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	4.11319792356479	bayes_pls_golite062009
glucosidase activity	3.69195576225095	bayes_pls_golite062009
beta-glucosidase activity	3.14931331494576	bayes_pls_golite062009
chitinase activity	2.45357334610104	bayes_pls_golite062009
alpha-amylase activity	2.09193270404736	bayes_pls_golite062009
amylase activity	2.03484942782894	bayes_pls_golite062009
catalytic activity	1.85569074294201	bayes_pls_golite062009
hexosaminidase activity	1.26857012744249	bayes_pls_golite062009
hydrolase activity	1.22608062881808	bayes_pls_golite062009
carbohydrate binding	0.4998423581103	bayes_pls_golite062009
binding	0.442009020636084	bayes_pls_golite062009
hyalurononglucosaminidase activity	0.123700697143861	bayes_pls_golite062009
receptor binding	0.0577582382963624	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [297-318]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YQVFASDQLE RSIDEHIKVA CE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [336-398]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAALTDCTKW LNSVGFGARY DGSWVNGDQT SSYIGSCANN DDIAYWSDER KENTRRYVEA  60
   61 QLD

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [414-448]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESSLEWDAQR LMFNGLFPQP LTDRKYPNQC GTISN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1454.0
Match:	1cz1A_
Description:	Exo-beta-(1,3)-glucanase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: