YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|194191900, gi...
Organism:	Drosophila simulans
Length:	276 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|194191900, gi....

Description	E-value	Query Range	Subject Range
PHB_CHICK - Prohibitin OS=Gallus gallus GN=PHB PE=1 SV=1	238.0	[0..1]	[272..1]
gi\|89272030, gi\|... - gi\|89272810\|emb\|CAJ82042.1\| prohibitin [Xenopus tropicalis], gi\|89272030\|emb\|CAJ83243.1\| prohibitin ...	236.0	[0..1]	[272..1]
gi\|74181431, gi\|... - gi\|74185218\|dbj\|BAE30089.1\| unnamed protein product [Mus musculus], gi\|74181431\|dbj\|BAE29988.1\| unna...	235.0	[0..1]	[272..1]
gi\|60829530 - gi\|60829530\|gb\|AAX36882.1\| prohibitin [synthetic construct]	234.0	[0..1]	[273..1]
gi\|33286931, gi\|... - gi\|41351079\|gb\|AAH65895.1\| Phb protein [Danio rerio], gi\|41152028\|ref\|NP_958454.1\| prohibitin [Danio...	234.0	[0..3]	[272..2]
gi\|32766612, gi\|... - gi\|32766612\|gb\|AAH54971.1\| MGC64447 protein [Xenopus laevis], gi\|148230088\|ref\|NP_001079819.1\| hypot...	234.0	[0..1]	[272..1]
gi\|61362617, gi\|... - gi\|61362624\|gb\|AAX42254.1\| prohibitin [synthetic construct], gi\|61362617\|gb\|AAX42253.1\| prohibitin [... HGNC:8912\|MIM:17... - null PHB - prohibitin PHB_BOVIN - Prohibitin OS=Bos taurus GN=PHB PE=2 SV=1 gi\|158906128, gi... - gi\|160333845\|ref\|NP_001103918.1\| prohibitin [Felis catus], gi\|158906128\|gb\|ABW82705.1\| prohibitin [F... gi\|158442066, gi... - gi\|158819069\|ref\|NP_001103649.1\| prohibitin [Canis lupus familiaris], gi\|158442066\|gb\|ABW38778.1\| pr... gi\|109114258, gi... - gi\|109114260\|ref\|XP_001093569.1\| PREDICTED: similar to prohibitin isoform 7 [Macaca mulatta], gi\|109... ENSCJAT00000014086 - null gi\|114666273, gi... - gi\|55646807\|ref\|XP_511949.1\| PREDICTED: prohibitin isoform 7 [Pan troglodytes], gi\|114666277\|ref\|XP_...	234.0	[0..1]	[272..1]
gi\|149053617, gi... - gi\|62656822\|ref\|XP_220756.3\| PREDICTED: similar to prohibitin [Rattus norvegicus], gi\|157786666\|ref\|...	234.0	[0..1]	[267..1]

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Predicted Domain #1

Region A:
Residues: [1-198]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAQFFNRIG QMGLGVAVLG GVVNSALYNV EGGHRAVIFD RFTGIKENVV GEGTHFFIPW  60
   61 VQRPIIFDIR SQPRNVPVIT GSKDLQNVNI TLRILYRPIP DQLPKIYTIL GQDYDERVLP 120
  121 SIAPEVLKAV VAQFDAGELI TQREMVSQRV SQELTVRAKQ FGFILDDISL THLTFGREFT 180
  181 LAVEMKQVAQ QEAEKARF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.69897
Match:	1winA
Description:	Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.10215477176861	bayes_pls_golite062009
protein binding	0.769979871341236	bayes_pls_golite062009
structural molecule activity	0.591437172549816	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [199-276]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVEKAEQQKL ASIISAEGDA EAAGLLAKSF GEAGDGLVEL RRIEAAEDIA YQLSRSRGVA  60
   61 YLPSGQSTLL NLPSTIAQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: