YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213586463
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E98-0664
Length:	365 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213586463.

Description	E-value	Query Range	Subject Range
gi\|56127852, gi\|... - gi\|56413595\|ref\|YP_150670.1\| N-ethylmaleimide reductase [Salmonella enterica subsp. enterica serovar... gi\|197093996, gi... - gi\|197362519\|ref\|YP_002142156.1\| N-ethylmaleimide reductase [Salmonella enterica subsp. enterica ser... gi\|168264729, gi... - gi\|205346855\|gb\|EDZ33486.1\| N-ethylmaleimide reductase [Salmonella enterica subsp. enterica serovar ...	0.0	[1..365]	[1..365]
gi\|77959187 - gi\|77959187\|ref\|ZP_00823209.1\| COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family [Yersi...	0.0	[1..365]	[1..365]
gi\|194405865, gi... - gi\|194447561\|ref\|YP_002045474.1\| N-ethylmaleimide reductase [Salmonella enterica subsp. enterica ser... gi\|197242562, gi... - gi\|197264307\|ref\|ZP_03164381.1\| N-ethylmaleimide reductase [Salmonella enterica subsp. enterica sero... gi\|205327852, gi... - gi\|205327852\|gb\|EDZ14616.1\| N-ethylmaleimide reductase [Salmonella enterica subsp. enterica serovar ... gi\|168240950, gi... - gi\|205339189\|gb\|EDZ25953.1\| N-ethylmaleimide reductase [Salmonella enterica subsp. enterica serovar ... gi\|16419956, gi\|... - gi\|16764784\|ref\|NP_460399.1\| N-ethylmaleimide reductase [Salmonella typhimurium LT2], gi\|16419956\|gb... lcl\|NC_016856.1_... - [gene=nemA] [protein=N-ethylmaleimide reductase] [protein_id=YP_005237306.1] [location=complement(15...	0.0	[1..365]	[1..365]
gi\|77961716 - gi\|77961716\|ref\|ZP_00825548.1\| COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family [Yersi...	0.0	[1..365]	[1..365]
gi\|77633724, gi\|... - gi\|77633724\|ref\|ZP_00795843.1\| COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family [Yersi... gi\|153950748, gi... - gi\|77629364\|ref\|ZP_00791950.1\| COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family [Yersi... gi\|165990445, gi... - gi\|166010743\|ref\|ZP_02231641.1\| oxidoreductase, FAD/FMN-binding [Yersinia pestis biovar Antiqua str.... gi\|165921640, gi... - gi\|165926419\|ref\|ZP_02222251.1\| oxidoreductase, FAD/FMN-binding [Yersinia pestis biovar Orientalis s... gi\|149292123, gi... - gi\|149365710\|ref\|ZP_01887745.1\| NADH:flavin oxidoreductase / NADH oxidase family protein [Yersinia p... gi\|145598070, gi... - gi\|145598070\|ref\|YP_001162146.1\| N-ethylmaleimide reductase [Yersinia pestis Pestoides F], gi\|145209... gi\|108807720, gi... - gi\|108807720\|ref\|YP_651636.1\| N-ethylmaleimide reductase [Yersinia pestis Antiqua], gi\|108779633\|gb\|... gi\|229680641, gi... - gi\|229902306\|ref\|ZP_04517426.1\| NADH:flavin oxidoreductase / NADH oxidase family protein [Yersinia p... gi\|89103792, gi\|... - gi\|89103792\|ref\|ZP_01176356.1\| COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family [Yersi... gi\|167400926, gi... - gi\|167400926\|ref\|ZP_02306432.1\| oxidoreductase, FAD/FMN-binding [Yersinia pestis biovar Antiqua str.... gi\|166207777, gi... - gi\|166210597\|ref\|ZP_02236632.1\| oxidoreductase, FAD/FMN-binding [Yersinia pestis biovar Antiqua str.... gi\|25325966 - pir\|\|AD0290 NADH flavin oxidoreductase / NADH oxidase family protein YPO2379 [imported] - Yersinia p... gi\|167470352 - gi\|167470352\|ref\|ZP_02335056.1\| oxidoreductase, FAD/FMN-binding protein [Yersinia pestis FV-1] gi\|229837903, gi... - gi\|229837903\|ref\|ZP_04458062.1\| NADH:flavin oxidoreductase / NADH oxidase family protein [Yersinia p... gi\|166958908, gi... - gi\|167422096\|ref\|ZP_02313849.1\| oxidoreductase, FAD/FMN-binding [Yersinia pestis biovar Orientalis s... gi\|229701952, gi... - gi\|229895064\|ref\|ZP_04510241.1\| NADH:flavin oxidoreductase / NADH oxidase family protein [Yersinia p... gi\|218929470, gi... - gi\|218929470\|ref\|YP_002347345.1\| N-ethylmaleimide reductase [Yersinia pestis CO92], gi\|16122602\|ref\|... gi\|229688510, gi... - gi\|229898466\|ref\|ZP_04513612.1\| NADH:flavin oxidoreductase / NADH oxidase family protein [Yersinia p... gi\|45441957, gi\|... - gi\|45441957\|ref\|NP_993496.1\| N-ethylmaleimide reductase [Yersinia pestis biovar Microtus str. 91001]... gi\|170024110, gi... - gi\|170024110\|ref\|YP_001720615.1\| N-ethylmaleimide reductase [Yersinia pseudotuberculosis YPIII], gi\|...	0.0	[1..365]	[1..365]
gi\|238792289, gi... - gi\|77979560\|ref\|ZP_00834978.1\| COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family [Yersi...	0.0	[1..365]	[1..365]
gi\|62180025, gi\|... - gi\|62180025\|ref\|YP_216442.1\| N-ethylmaleimide reductase [Salmonella enterica subsp. enterica serovar...	0.0	[1..365]	[1..365]
gi\|238787145, gi... - gi\|77975305\|ref\|ZP_00830841.1\| COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family [Yersi...	0.0	[1..365]	[1..365]
gi\|38674622 - gi\|38674622\|gb\|AAR26328.1\| pentaerythritol tetranitrate reductase [Enterobacter cloacae]	0.0	[1..365]	[1..365]

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Predicted Domain #1

Region A:
Residues: [1-365]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSAKLFTPL KVGAITATNR VFMAPLTRLR SIEPGDIPTP LMAEYYRQRA SAGLIISEAT  60
   61 QISAQAKGYA GAPGLHSDEQ IAAWKKITQG VHAQGGHMAV QLWHTGRISH ASLQPGGQAP 120
  121 VAPSAINAGT RTSLRDENGQ AIRVETSTPR ALDTHEIPGI VNDFRQAIAN AREAGFDLVE 180
  181 LHSAHGYLLH QFLSPSSNHR TDRYGGSVEN RARLVLEVVD AGIKEWGADR IGIRLSPVGT 240
  241 FQNVDNGPNE EADALYLIEA LGKRGIAYLH MSEPDWAGGE PYSDAFREKV RARFHGPIIG 300
  301 AGAYTPEKAE DLIEKGLIDA VAFGRDYIAN PDLVARLQRK AELNPQRPES FYGGGAEGYT 360
  361 DYPTL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	111.0
Match:	1gvoA
Description:	Pentaerythritol tetranirate reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on the CH-CH group of donors	2.11027907327307	bayes_pls_golite062009
catalytic activity	1.94749091175302	bayes_pls_golite062009
binding	1.2785695107981	bayes_pls_golite062009
coenzyme binding	0.99234662301893	bayes_pls_golite062009
oxidoreductase activity	0.84996661470385	bayes_pls_golite062009
nucleic acid binding	0.350068675013616	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.0276497014195508	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: