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View Structure Prediction Details

Protein: gi|220952732, gi...
Organism: synthetic construct
Length: 659 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220952732, gi....

Description E-value Query
Range
Subject
Range
gi|21064419 - gi|21064419|gb|AAM29439.1| RE25878p [Drosophila melanogaster]
643.0 [0..1] [659..1]

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Predicted Domain #1
Region A:
Residues: [1-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWNSEPTHRQ HHQHNGNSTS GGPPAKQLGM TSAISLAEPR PEDLQRTDEL RGSLEPYNVF  60
   61 ESQDELNHRM EILAKLNTLV KQWVKEISVS KNMPESAAEK LGGKIYTFGS YRLGVHHKGA 120
  121 DIDALCVAPR NIERTDYFQS FFEVLKKQPE VTECRSVEEA FVPVIKMNFD GIEIDLLFAR 180
  181 LSLKEIPDDF DLRDDNLLRN LDHRSVRSLN GCRVTDEILA LVPNIENFRL ALRTIKLWAK 240
  241 KHGIYSNSLG YFGGVTWAML VARTCQLYPN AAAATLVHKF FLVFSRWKWP NPVLLKHPDN 300
  301 VNLRFQVWDP RVNASDRYHL MPIITPAYPQ QNSTFNVSES TKKVILTEFN RGMNITDEIM 360
  361 LGRIPWERLF EAPSFFYRYR HFIVLLVNSQ TADDHLEWCG LVESKVRLLI GNLERNPHIA 420
  421 LAHVNPKCFE FKKGQSANNS QNNSGNEDDL KQSQGNQSAV TSAPFCSMWF IGLEFERSEN 480
  481 LNVDLTESIQ NFTEHVMMHG VNIKMLKEGM TIDARHVKRK QLSLYLDSDF LKRERKSMES 540
  541 HNNFNNTLLA N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 155.0
Match: 1q78A
Description: Crystal structure of poly(A) polymerase in complex with 3'-dATP and magnesium chloride
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.46555984694381 bayes_pls_golite062009
nucleotidyltransferase activity 1.61922062344227 bayes_pls_golite062009
nucleic acid binding 1.43322212500405 bayes_pls_golite062009
polynucleotide adenylyltransferase activity 1.24026612395993 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.08480919674453 bayes_pls_golite062009
DNA binding 0.920001549206154 bayes_pls_golite062009
binding 0.888087430062829 bayes_pls_golite062009
catalytic activity 0.75232920999699 bayes_pls_golite062009
transferase activity 0.432029324907561 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [552-659]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKRLSTELAQ SQDPLPPGQQ PSSGNRGRDS GAKIQRLSDS LTEENSNASS DMGAGTPTTP  60
   61 TTAQLSAPSF KSSGKNGSEI DVVEQEPTQP HNNGNASSNT TTTEVACS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle