YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213425217
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E02-1180
Length:	229 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213425217.

Description	E-value	Query Range	Subject Range
gi\|224585541, gi... - gi\|224585541\|ref\|YP_002639340.1\| tRNA (guanosine-2'-O)-methyltransferase [Salmonella enterica subsp.... gi\|206710783, gi... - gi\|207858980\|ref\|YP_002245631.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. e... gi\|200387615, gi... - gi\|200387615\|ref\|ZP_03214227.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. en... gi\|194735347, gi... - gi\|194735347\|ref\|YP_002116686.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. e... gi\|238910216 - gi\|238910216\|ref\|ZP_04654053.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. en... gi\|194469893, gi... - gi\|194469893\|ref\|ZP_03075877.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. en... gi\|194448230, gi... - gi\|194448230\|ref\|YP_002047774.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. e... gi\|62129870, gi\|... - gi\|62182237\|ref\|YP_218654.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. enter... gi\|194444680, gi... - gi\|194444680\|ref\|YP_002042992.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. e... gi\|168818425, gi... - gi\|205344462\|gb\|EDZ31226.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. enteri... gi\|168260501, gi... - gi\|205350250\|gb\|EDZ36881.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. enteri... gi\|168241923, gi... - gi\|205339031\|gb\|EDZ25795.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. enteri... gi\|168235358, gi... - gi\|197291598\|gb\|EDY30950.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. enteri... gi\|205332504, gi... - gi\|205332504\|gb\|EDZ19268.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. enteri... gi\|205325898, gi... - gi\|205325898\|gb\|EDZ13737.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. enteri...	4.0E-70	[1..229]	[1..229]
gi\|187771590, gi... - gi\|187771590\|gb\|EDU35434.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str. EC4... gi\|168766072, gi... - gi\|189364456\|gb\|EDU82875.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str. EC4... gi\|189374444, gi... - gi\|189374444\|gb\|EDU92860.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str. EC8... gi\|168779807, gi... - gi\|189002529\|gb\|EDU71515.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str. EC4... gi\|170018119, gi... - gi\|170018119\|ref\|YP_001723073.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli ATCC 8739],... gi\|189378798, gi... - gi\|189378798\|gb\|EDU97214.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str. EC5... gi\|13364001, gi\|... - gi\|15833780\|ref\|NP_312553.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str. Sa... gi\|195936212 - gi\|195936212\|ref\|ZP_03081594.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str.... gi\|110807671, gi... - gi\|110807671\|ref\|YP_691191.1\| tRNA guanosine-2'-O-methyltransferase [Shigella flexneri 5 str. 8401],... gi\|169890993, gi... - gi\|170083158\|ref\|YP_001732478.1\| tRNA (guanosine-2'-O-)-methyltransferase [Escherichia coli str. K-1... gi\|238863706, gi... - gi\|238902742\|ref\|YP_002928538.1\| tRNA (Guanosine-2'-O-)-methyltransferase [Escherichia coli BW2952],... gi\|242379175, gi... - gi\|251786902\|ref\|YP_003001206.1\| hypothetical protein B21_03460 [Escherichia coli BL21], gi\|24237917... gi\|253322551, gi... - gi\|254290329\|ref\|YP_003056077.1\| tRNA (Guanosine-2'-O-)-methyltransferase [Escherichia coli BL21(DE3... gi\|226838817, gi... - gi\|254038852\|ref\|ZP_04872904.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia sp. 1_1_43], gi\|2... gi\|254163579, gi... - gi\|254163579\|ref\|YP_003046687.1\| tRNA (Guanosine-2'-O-)-methyltransferase [Escherichia coli B str. R... gi\|168748698, gi... - gi\|188017001\|gb\|EDU55123.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str. EC4... gi\|254795606, gi... - gi\|254795606\|ref\|YP_003080443.1\| tRNA (Guanosine-2'-O-)-methyltransferase [Escherichia coli O157:H7 ... gi\|189369492, gi... - gi\|189369492\|gb\|EDU87908.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str. EC4... gi\|189359254, gi... - gi\|189359254\|gb\|EDU77673.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str. EC4... gi\|124528992, gi... - gi\|124528992\|ref\|ZP_01700138.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli B], gi\|12450... TRMH_ECOLI - tRNA guanosine-2'-O-methyltransferase (EC 2.1.1.34) (tRNA [Gm18] methyltransferase) - Escherichia co... gi\|188491145, gi... - gi\|75514286\|ref\|ZP_00736594.1\| COG0566: rRNA methylases [Escherichia coli 53638], gi\|188495946\|ref\|Z... gi\|208812795, gi... - gi\|208812795\|ref\|ZP_03254124.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str.... gi\|73857591, gi\|... - gi\|74314114\|ref\|YP_312533.1\| tRNA guanosine-2'-O-methyltransferase [Shigella sonnei Ss046], gi\|73857... gi\|208806132, gi... - gi\|208806132\|ref\|ZP_03248469.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str.... gi\|24114921, gi\|... - gi\|24114921\|ref\|NP_709431.1\| tRNA guanosine-2'-O-methyltransferase [Shigella flexneri 2a str. 301], ... gi\|190902169, gi... - gi\|75229042\|ref\|ZP_00715626.1\| COG0566: rRNA methylases [Escherichia coli B7A], gi\|191167826\|ref\|ZP_... gi\|209398863, gi... - gi\|209398863\|ref\|YP_002273131.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str... TRMH_SHIFL - tRNA (guanosine(18)-2'-O)-methyltransferase OS=Shigella flexneri GN=trmH PE=3 SV=1 gi\|193063862, gi... - gi\|75258192\|ref\|ZP_00729640.1\| COG0566: rRNA methylases [Escherichia coli E22], gi\|193063862\|ref\|ZP_... gi\|208739228, gi... - gi\|208819105\|ref\|ZP_03259425.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str.... TRMH_ECO57 - tRNA (guanosine(18)-2'-O)-methyltransferase OS=Escherichia coli O157:H7 GN=trmH PE=3 SV=1 gi\|217324129, gi... - gi\|217324129\|ref\|ZP_03440213.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str.... gi\|30043334, gi\|... - gi\|30065073\|ref\|NP_839244.1\| tRNA guanosine-2'-O-methyltransferase [Shigella flexneri 2a str. 2457T]... gi\|209914383, gi... - gi\|209921124\|ref\|YP_002295208.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli SE11], gi\|2... gi\|15804192, gi\|... - gi\|15804192\|ref\|NP_290231.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 EDL933]... gi\|82546080, gi\|... - gi\|82546080\|ref\|YP_410027.1\| tRNA guanosine-2'-O-methyltransferase [Shigella boydii Sb227], gi\|81247... gi\|218362982, gi... - gi\|218556214\|ref\|YP_002389127.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli IAI1], gi\|2... EG10967 - tRNA mG18-2'-O-methyltransferase, SAM-dependent / tRNA mG18 2'-O-methyltransferase, SAM-dependent gi\|85676392, gi\|... - gi\|89110361\|ref\|AP_004141.1\| tRNA (Guanosine-2'-O-)-methyltransferase [Escherichia coli str. K-12 su... gi\|218551178, gi... - gi\|218551178\|ref\|YP_002384969.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia fergusonii ATCC ... gi\|75197554, gi\|... - gi\|75197554\|ref\|ZP_00707624.1\| COG0566: rRNA methylases [Escherichia coli HS], gi\|157163132\|ref\|YP_0... gi\|75208677, gi\|... - gi\|75208677\|ref\|ZP_00708974.1\| COG0566: rRNA methylases [Escherichia coli B171], gi\|194430057\|ref\|ZP... gi\|194425496, gi... - gi\|83588502\|ref\|ZP_00927126.1\| COG0566: rRNA methylases [Escherichia coli 101-1], gi\|194435953\|ref\|Z... EG10967 - tRNA mG18-2'-O-methyltransferase, SAM-dependent / tRNA mG18 2'-O-methyltransferase, SAM-dependent	5.0E-70	[1..229]	[1..229]
gi\|91213169, gi\|... - gi\|91213169\|ref\|YP_543155.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli UTI89], gi\|9107... gi\|157078987, gi... - gi\|75188409\|ref\|ZP_00701676.1\| COG0566: rRNA methylases [Escherichia coli E24377A], gi\|157156957\|ref... gi\|115515047, gi... - gi\|117625923\|ref\|YP_859246.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli APEC O1], gi\|1... gi\|218560723, gi... - gi\|218560723\|ref\|YP_002393636.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli S88], gi\|21... gi\|218429498, gi... - gi\|218691934\|ref\|YP_002400146.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli ED1a], gi\|2... gi\|26110728, gi\|... - gi\|26250298\|ref\|NP_756338.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli CFT073], gi\|261...	5.0E-70	[1..229]	[1..229]
gi\|75179690, gi\|... - gi\|75179690\|ref\|ZP_00699677.1\| COG0566: rRNA methylases [Shigella boydii BS512], gi\|187732340\|ref\|YP...	5.0E-70	[1..229]	[1..229]
gi\|16422312, gi\|... - gi\|16767028\|ref\|NP_462643.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella typhimurium LT2], gi\|... gi\|167992299, gi... - gi\|205329407\|gb\|EDZ16171.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. enteri... lcl\|NC_016856.1_... - [gene=spoU] [protein=tRNA guanosine-2'-O-methyltransferase] [protein_id=YP_005239988.1] [location=39...	8.0E-70	[1..229]	[1..229]
gi\|170519543, gi... - gi\|170681825\|ref\|YP_001745951.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli SMS-3-5], g... gi\|218707285, gi... - gi\|218707285\|ref\|YP_002414804.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli UMN026], gi... gi\|110643892, gi... - gi\|110643892\|ref\|YP_671622.1\| tRNA guanosine-2'-O-methyltransferase [Escherichia coli 536], gi\|11034... gi\|190909145, gi... - gi\|75242570\|ref\|ZP_00726314.1\| COG0566: rRNA methylases [Escherichia coli F11], gi\|191170337\|ref\|ZP_...	9.0E-70	[1..229]	[1..229]
gi\|193070365, gi... - gi\|75234809\|ref\|ZP_00719112.1\| COG0566: rRNA methylases [Escherichia coli E110019], gi\|193070365\|ref...	1.0E-69	[1..229]	[1..229]
gi\|83571438, gi\|... - gi\|83571438\|ref\|ZP_00922878.1\| COG0566: rRNA methylases [Shigella dysenteriae 1012], gi\|194431220\|re...	1.0E-69	[1..229]	[1..229]
gi\|56129890, gi\|... - gi\|56415633\|ref\|YP_152708.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. enter... gi\|197364560, gi... - gi\|197364560\|ref\|YP_002144197.1\| tRNA guanosine-2'-O-methyltransferase [Salmonella enterica subsp. e...	2.0E-69	[1..229]	[1..229]
gi\|82779142, gi\|... - gi\|82779142\|ref\|YP_405491.1\| tRNA guanosine-2'-O-methyltransferase [Shigella dysenteriae Sd197], gi\|...	8.0E-69	[1..229]	[1..229]

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Predicted Domain #1

Region A:
Residues: [1-229]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPKRYARIC EMLARRQPDL TVCMEQVHKP HNVSAIIRTA DAVGVHEVHA IWPGSRMRTM  60
   61 ASAAAGSNSW VQVKTHRTID DAVAHLKGRG MQILATHLSD KAVDFREIDY TRPTCILMGQ 120
  121 EKTGITQEAL DLADRDIIIP MIGMVQSLNV SVASALILYE AQRQRQNAGM YLRENSMLPE 180
  181 DEQQRLLFEG GYPVLAKVAK RKGLPYPRVN QQGEIDADAD WWATMQAAG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.39794
Match:	1v2xA
Description:	TrmH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	4.77771076540343	bayes_pls_golite062009
methyltransferase activity	4.0901595540349	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.01958090893547	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.59156540645412	bayes_pls_golite062009
tRNA methyltransferase activity	2.52700462137917	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	2.29844424181442	bayes_pls_golite062009
tRNA (guanine-N1-)-methyltransferase activity	2.0947794364355	bayes_pls_golite062009
rRNA methyltransferase activity	1.86192852581774	bayes_pls_golite062009
transferase activity	1.84002196534744	bayes_pls_golite062009
catalytic activity	1.16774040077235	bayes_pls_golite062009
N-methyltransferase activity	0.0655574594365502	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: