YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|221229838, gi...
Organism:	Mycobacterium leprae Br4923
Length:	395 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|221229838, gi....

Description	E-value	Query Range	Subject Range
gi\|54018048, gi\|... - gi\|54026540\|ref\|YP_120782.1\| molybdopterin biosynthesis-like protein MoeZ [Nocardia farcinica IFM 10...	310.0	[0..3]	[395..2]
gi\|83633661, gi\|... - gi\|83645618\|ref\|YP_434053.1\| molybdopterin/thiamine biosynthesis family protein [Hahella chejuensis ...	302.0	[0..8]	[395..3]
gi\|48834858 - ref\|ZP_00291862.1\| COG0476: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine bi... gi\|71914656, gi\|... - gi\|72160924\|ref\|YP_288581.1\| molybdopterin biosynthesis-like protein MoeZ [Thermobifida fusca YX], g...	301.0	[0..7]	[395..2]
gi\|45545541, gi\|... - gi\|68563155\|ref\|ZP_00602357.1\| UBA/THIF-type NAD/FAD binding fold:Rhodanese-like:MoeZ/MoeB [Rubrobac...	293.0	[0..11]	[395..8]
gi\|111023324, gi... - gi\|111023324\|ref\|YP_706296.1\| molybdopterin biosynthesis-like protein MoeZ [Rhodococcus jostii RHA1]...	291.0	[0..4]	[395..9]
gi\|29606732, gi\|... - gi\|29829624\|ref\|NP_824258.1\| molybdopterin biosynthesis-like protein MoeZ [Streptomyces avermitilis ...	290.0	[0..7]	[395..2]
gi\|106891733, gi... - gi\|148654884\|ref\|YP_001275089.1\| UBA/THIF-type NAD/FAD binding protein [Roseiflexus sp. RS-1], gi\|14...	289.0	[0..15]	[395..3]
gi\|82702101, gi\|... - gi\|82702101\|ref\|YP_411667.1\| UBA/THIF-type NAD/FAD binding fold [Nitrosospira multiformis ATCC 25196...	289.0	[0..8]	[395..3]
gi\|9714466, gi\|2... - gi\|9714466\|emb\|CAC01308.1\| putative sulfurylase [Streptomyces coelicolor A3(2)], gi\|21223547\|ref\|NP_...	289.0	[0..7]	[395..2]
gi\|89342252, gi\|... - gi\|89342252\|ref\|ZP_01194491.1\| UBA/THIF-type NAD/FAD binding fold:Rhodanese-like:MoeZ/MoeB [Mycobact...	288.0	[0..5]	[395..2]

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Predicted Domain #1

Region A:
Residues: [1-144]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTSSTSLPP LVEPAGQLSR DEVIRYSRHL IIPDIGVDGQ MRLKSARVLV IGAGGLGAPV  60
   61 LLYLAAAGVG TIGIIDFDVV DESNLQRQII HGVADVGRSK AQSARDSIVA INPLVQVRLH 120
  121 EFRLESSNVV NLFKQYDLIV DGTD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.39794
Match:	1jw9B
Description:	Molybdenum cofactor biosynthesis protein MoeB
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [145-395]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFATRYLIND AAVLAKKPYV WGSLYRFEGQ VSVFWEDAPD GLGLNYRDLY LEPPPPGMVP  60
   61 SCAEGGVLGI VCASIASVMG TEAIKLITGI GAPLLGRLMI YNALEMSYRR IRIHKDPSRP 120
  121 KITELTDYQQ FCGVVSDDAA QVATGSIVTP RELRELLDSG KKLALIDVRE PVEWDIVHID 180
  181 GAQLIPRSLI NSGEGLAKLP QDRMSVLYCK TGVRSAETLA TVKKAGFSDA VHLQGGIVAW 240
  241 AKQVQPDMVI Y

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.69897
Match:	1urhA
Description:	The "Rhodanese" fold and catalytic mechanism of 3-mercaptopyruvate sulfotransferases: Crystal structure of SseA from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
thiosulfate sulfurtransferase activity	4.07143118207301	bayes_pls_golite062009
binding	1.53109235820839	bayes_pls_golite062009
transferase activity	1.00600613068372	bayes_pls_golite062009
phosphoprotein phosphatase activity	0.765055251775806	bayes_pls_golite062009
catalytic activity	0.687308230067573	bayes_pls_golite062009
phosphatase activity	0.596156043915887	bayes_pls_golite062009
sulfurtransferase activity	0.419061082217665	bayes_pls_golite062009
protein binding	0.415782692658192	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.41208200336081	bayes_pls_golite062009
protein tyrosine phosphatase activity	0.224132693583958	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: